A method for separation and preparation of characteristic components of Peruvian extract
A technology of Peruvian extract and separation column, which is applied in the field of separation and preparation of volatile components of Peruvian extract, can solve the problems of unreported separation and preparation methods, and no reports on the application of characteristic components, and achieves simple operation and high yield. high effect
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Embodiment 1
[0030] Eluent pretreatment: Use a re-distillation device to re-distill petroleum ether and ethyl acetate to remove high-boiling impurities. The redistillation temperature of petroleum ether is 80°C. The redistillation temperature of ethyl acetate was 90°C.
[0031] Wet column packing: Weigh 120g of silica gel into a 500mL beaker, add a mixed solvent of petroleum ether and ethyl acetate with a volume ratio of 12:1, stir well and pour it into a Φ0.26x70cm separation column at one time, and rinse repeatedly to make The silicone is evenly firm.
[0032] Sample loading: Weigh 0.6g of Peruvian extract into a 50mL eggplant-shaped bottle, add 2mL of ethyl acetate to dissolve and dilute, and then spread the diluted Peruvian extract on the silica gel surface slowly and evenly with a disposable dropper.
[0033] Gradient elution: use DHL-N computer digital display timing constant flow pump to control the flow rate of eluent to 3mL / min, according to the volume ratio of petroleum ether a...
Embodiment 2
[0038] Eluent pretreatment: Use a re-distillation device to re-distill petroleum ether and ethyl acetate to remove high-boiling impurities. The redistillation temperature of petroleum ether is 80°C. The redistillation temperature of ethyl acetate was 90°C.
[0039] Wet column packing: Weigh 120g of silica gel into a 500mL beaker, add a mixed solvent of petroleum ether and ethyl acetate with a volume ratio of 11:1, stir well and pour it into a Φ0.26x70cm separation column at one time, and rinse repeatedly to make The silicone is evenly firm.
[0040] Sample loading: Weigh 0.6g of Peruvian extract into a 50mL eggplant-shaped bottle, add 2mL of ethyl acetate to dissolve and dilute, and then spread the diluted Peruvian extract on the silica gel surface slowly and evenly with a disposable dropper.
[0041] Gradient elution: use DHL-N computer digital display timing constant flow pump to control the flow rate of eluent to 3mL / min, according to the volume ratio of petroleum ether a...
Embodiment 3
[0046] Eluent pretreatment: Use a re-distillation device to re-distill petroleum ether and ethyl acetate to remove high-boiling impurities. The redistillation temperature of petroleum ether is 80°C. The redistillation temperature of ethyl acetate was 90°C.
[0047] Wet column packing: Weigh 120g of silica gel into a 500mL beaker, add a mixed solvent of petroleum ether and ethyl acetate with a volume ratio of 10:1, stir well and pour it into a Φ0.26x70cm separation column at one time, and rinse repeatedly to make The silicone is evenly firm.
[0048] Sample loading: Weigh 0.6g of Peruvian extract into a 50mL eggplant-shaped bottle, add 2mL of ethyl acetate to dissolve and dilute, and then spread the diluted Peruvian extract on the silica gel surface slowly and evenly with a disposable dropper.
[0049] Gradient elution: use DHL-N computer digital display timing constant flow pump to control the flow rate of eluent to 3mL / min, according to the volume ratio of petroleum ether a...
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