Portable micro-needle array drug patch and preparation method and transdermal drug delivery method thereof

Abstract

The invention discloses a portable micro-needle array drug patch and a preparation method and transdermal drug delivery method thereof. An intelligent portable device is used as a power source, a current controller and a bluetooth IC module are embedded in an electrode slice, the current controller is in communication connection with the intelligent portable device through the bluetooth IC module,and the current controller controls the electric current flow transmitted to a micro-needle array according to command information sent by the intelligent portable device. The problem of large and expensive exogenous equipment in the existing permeation enhancing technology is solved, the portable micro-needle array drug patch is portable, and the transdermal controlled release of drug can be effectively realized by controllable and intelligent means.

Description

technical field [0001] The invention relates to the field of biomedical engineering, in particular to a portable microneedle array patch, a preparation method thereof, and a transdermal administration method. Background technique [0002] With the development of biotechnology, transdermal drug delivery has become a new drug delivery method. Transdermal drug delivery is to paste the drug on the skin surface in the form of a coating agent, and use the penetration of the skin for drug delivery. At present, the microneedle array patch has created a new way of transdermal drug delivery, which integrates the three processes of coating, puncture, and transmission, and can be pressed multiple times at regular intervals to achieve the purpose of long-term continuous drug delivery. [0003] In order to effectively solve the "hysteresis" of the existing microneedle array patch drug entering the human body, Chinese patent 201710091904.3 provides a patch that combines electrodes with mi...

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Problems solved by technology

[0003] In order to effectively solve the "hysteresis" of the existing microneedle array patch drug entering the human body, Chinese patent 201710091904.3 provides a patch that combines electrodes with microneedle array patch to improve the rate and speed of transdermal drug delivery. The effect makes the drug introduced into the body by the microneedle pass through the tissue smoothly and quickly, speeding up the penetration of the drug and the absorption rate of the drug by the skin, but there are disadvantages of large exogenous equipment and inconvenient use

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