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Collagen tripeptide for skin emergency repair and preparation method thereof

A collagen tripeptide, an emergency technology, applied in skin care preparations, chemical instruments and methods, specific peptides, etc., can solve the problem of narrow source of collagen peptide raw materials

Active Publication Date: 2021-07-06
艾苛密(上海)健康科技股份有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0009] The invention provides a collagen tripeptide for emergency repair of skin and a preparation method thereof. The collagen tripeptide is prepared by double-enzyme hydrolysis using gelatin prepared from mussels, which effectively overcomes the narrow source of collagen peptide raw materials in the prior art. question

Method used

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  • Collagen tripeptide for skin emergency repair and preparation method thereof
  • Collagen tripeptide for skin emergency repair and preparation method thereof
  • Collagen tripeptide for skin emergency repair and preparation method thereof

Examples

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Embodiment 1

[0054] A collagen tripeptide for emergency skin repair, which is prepared from Xunshi muscle clam gelatin.

[0055] The preparation steps of Xunshi muscle clam gelatin are as follows:

[0056] (1) Cleaning: the clam meat is separated from the shell, washed with water with 5 times the weight of the clam meat, soaked in water with 5 times the weight of the clam meat after washing for 2 hours, and then taken out for later use;

[0057] (2) Pretreatment: Use a tissue homogenizer to homogenize the cleaned clam meat, homogenate at a speed of 10,000 rpm for 3 minutes, add water twice the mass of clam meat, heat to 80°C, and keep 15 minutes to obtain the pretreatment solution;

[0058] (3) Degradation by glucoamylase: adjust the pH value of the pretreatment solution to 4.2 with 0.02mol / L hydrochloric acid solution, and adjust the temperature to 65° C. at the same time, add 3% glucoamylase to enzymatically hydrolyze the mass of Muscle chinensis clam meat for 3 hours to obtain enzymat...

Embodiment 2

[0067] A collagen tripeptide for emergency skin repair, which is prepared from Xunshi muscle clam gelatin.

[0068] The preparation steps of Xunshi muscle clam gelatin are as follows:

[0069] (1) Cleaning: the clam meat is separated from the shell, washed with water with 5 times the weight of the clam meat, soaked in water with 5 times the weight of the clam meat after washing for 2 hours, and then taken out for later use;

[0070] (2) Pretreatment: Use a tissue homogenizer to homogenize the cleaned clam meat, homogenate at a speed of 10,000 rpm for 3 minutes, add water twice the mass of clam meat, heat to 80°C, and keep 15 minutes to obtain the pretreatment solution;

[0071] (3) Glucoamylase degradation: adjust the pH value of the pretreatment solution to 4.2 with 0.02mol / L hydrochloric acid solution, and adjust the temperature to 65°C at the same time, add 3% glucoamylase of the muscle mass of the musculus musculus for enzymolysis for 3 hours, and obtain the enzyme Solut...

Embodiment 3

[0082] A collagen tripeptide for emergency skin repair, which is prepared from Xunshi muscle clam gelatin.

[0083] The preparation steps of Xunshi muscle clam gelatin are as follows:

[0084] (1) Cleaning: the clam meat is separated from the shell, washed with water with 5 times the weight of the clam meat, soaked in water with 5 times the weight of the clam meat after washing for 2 hours, and then taken out for later use;

[0085] (2) Pretreatment: Use a tissue homogenizer to homogenize the cleaned clam meat, homogenate at a speed of 10,000 rpm for 3 minutes, add water twice the mass of clam meat, heat to 80°C, and keep 15 minutes to obtain the pretreatment solution;

[0086] (3) Glucoamylase degradation: adjust the pH value of the pretreatment solution to 4.2 with 0.02mol / L hydrochloric acid solution, and adjust the temperature to 65°C at the same time, add 3% glucoamylase of the muscle mass of the musculus musculus for enzymolysis for 3 hours, and obtain the enzyme Solut...

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Abstract

The invention provides a collagen tripeptide for emergency skin repair and a preparation method thereof, and belongs to the field of skin care preparations. The invention selects mussel family animal gelatin as a raw material, and prepares collagen tripeptide through a double-enzyme hydrolysis method, wherein both enzymes are plant proteases selected from bromelain, papain, fig protease and ginger protease. The invention also improves the preparation method of the raw material and the preparation method of the collagen peptide. The collagen tripeptide prepared by the present invention has small molecules, fast absorption, good transdermal absorbability, and the 24-hour transdermal absorption rate can reach 3780 μg / cm 2 , The 30-minute free radical scavenging rate can reach up to 86%, which can be used for emergency repair of the skin.

Description

technical field [0001] The invention relates to the field of skin care preparations, in particular to a collagen tripeptide for emergency skin repair and a preparation method thereof. Background technique [0002] As the main component of the extracellular matrix, collagen is a typical fibrous protein in multicellular animals, accounting for 25-30% of the total protein content in the body. It is the most abundant protein in animals and has special mechanical properties and biological characteristics. In recent years, with the continuous deepening of research on collagen, its application in the medical field, beauty industry and food industry has become more and more extensive. At present, collagen has been considered to be a product with excellent performance, wide application and great development value. High natural biomass. [0003] Collagen peptide can be completely dissolved in water, the aqueous solution has low viscosity, and it has fluidity even at a high concentrat...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): C07K14/78C12P21/06A61Q19/00A61Q19/08
CPCA61Q19/00A61Q19/08C07K14/78C12P21/06
Inventor 张露引
Owner 艾苛密(上海)健康科技股份有限公司
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