Skin barrier repairing lotion

A technology of skin barrier and skin repairing agent, applied in the field of cosmetics, which can solve the problems of organic reagent residue in cosmetics, easy to be affected by the external environment, and ineffective skin effect, so as to achieve protection from damage, short heating time, and retention Effects of nutrients and functional ingredients

Inactive Publication Date: 2019-03-08
GRF WUHAN BIOTECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The cosmetic uses more organic reagents when extracting plants, which easily leads to the residue of organic reagents in the cosmetics
[0005] Ceramide used alone can prevent moisture loss and moisturize. Carnosine has anti-aging effect and can protect skin cells from UVB damage. Therefore, ceramide and carnosine are often used as effective raw materials for cosmetics or skin care products, but Since the content of ceramide and carnosine contained in cosmetics and skin care products is less, and the surface of ceramide and carnosine in existing cosmetics / skin care products has not been subjected to surface protection treatment, the stability is poor, and the absorption rate of the skin is low. The effect is not obvious, and it cannot effectively penetrate the skin and act on cells to repair skin damage; at the same time, ceramide and carnosine are distributed in the auxiliary materials of cosmetics / skin care products in the form of single molecules, and there is no connection force between them , acting on the surface of the human skin is easily affected by the external environment, the repair effect on the skin is limited, and it cannot form a skin barrier to play a long-term barrier protection effect on the skin

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0030]This embodiment provides a skin barrier repair milk, which is composed of the following raw materials in parts by weight: 60 parts by weight of water, 8 parts by weight of moisturizer, 2 parts by weight of skin conditioner, 0.2 parts by weight of emulsifier, and 0.1 part by weight of thickener , 0.1 parts by weight of antioxidant, 0.055 parts by weight of plant extract, and 0.005 parts by weight of skin repairing agent.

[0031] The skin repair agent is composed of palmitoyl tripeptide-5, acetyl tetrapeptide-2, acetyl hexapeptide-8, oligopeptide-1, ceramide 3, ceramide 6II, and ceramide 1 in a weight ratio of 1:1 :1:2:3:3:3 Composition.

[0032] The preparation method of described skin restoration agent, comprises the following steps:

[0033] 1) Mix glycerin and emulsifier evenly at 60-80°C, and stir at 200rpm for 10-25min to form a uniform mixed solution;

[0034] 2) Add ceramide 3, ceramide 6II, and ceramide 1 to the mixed solution in step 1), and stir for 5-15 minu...

Embodiment 2

[0040] This embodiment provides a skin barrier repair milk. Compared with Embodiment 1, the difference is that the ceramide-polypeptide skin repair agent is wrapped with a moisturizing agent to make nanogel microcapsules by using a high-pressure homogenization method. ; The nanogel microcapsule has a double-layer structure, the center is the ceramide-polypeptide skin repair agent, and the outer layer is the moisturizing agent. The average particle diameter of the nanogel microcapsule is 50-200nm.

Embodiment 3

[0042] This embodiment provides a skin barrier repair milk. Compared with Example 1, the difference is that the preparation method of the plant component extract includes the following steps:

[0043] Put the dried plants in a crushing extractor with a motor power of 800-1800W, add ethanol, and crush the tissue at a speed of 6000-10000r / min. The extraction pressure is 20-50Mpa, the extraction temperature is 35-55°C, and the CO2 flow rate is 10-25L / h for CO2 supercritical fluid extraction. The time is 5-15min, the extract is collected, and the obtained extract is flashed and concentrated at 50-80°C and the vacuum degree is 0.090-0.095Mpa, and the flow rate is 150-300mL.min-1. Repeatedly Concentrate to 1 / 5-1 / 6 of the original volume, and vacuum-dry the concentrate to dry powder to obtain the plant component extract.

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Abstract

The invention discloses skin barrier repairing lotion. The skin barrier repairing lotion is prepared from the following raw materials: water, a humectant, a skin conditioning agent, an emulsifier, a thickening agent, an antioxidant, plant extract and a skin repairing agent, wherein the skin repairing agent is prepared from palmitoyl tripeptide-5, acetyl tetrapeptide-2, acetyl hexapeptide-8, oligopeptide-1, ceramide 3, ceramide 6II and ceramide 1. According to the skin barrier repairing lotion, the ceramide and polypeptide are prepared into a ceramide-polypeptide skin repairing agent with a net-shaped structure; when the ceramide-polypeptide skin repairing agent is used, a protection film can be formed on the surface of skin, the protection time on the skin is prolonged and the effect of askin barrier is realized; the ceramide-polypeptide skin repairing agent is prepared into nano-gel microcapsules and the ceramide-polypeptide skin repairing agent is protected, so that the stability isenhanced and the ceramide-polypeptide skin repairing agent effectively acts on skin cells and has a skin repairing effect.

Description

technical field [0001] The invention belongs to the technical field of cosmetics, in particular to a skin barrier repair milk. Background technique [0002] With aging and external adverse environmental stimuli, the appearance, physical characteristics and physiological functions of the skin change or deteriorate in various ways, the most notable changes include: increased fine lines and wrinkles, loss of elasticity, increased sagging , Loss of firmness, loss of color uniformity, and enhanced surface texture roughness. Less obvious but measurable changes are: a general decrease in cell and tissue viability, a decrease in the rate of cell replication, a decrease in blood flow to the skin, a decrease in moisture, accumulation of structural and functional errors; and a decrease in the skin's ability to rebuild and repair itself . [0003] Chinese Patent No. CN201810802205.X discloses a cosmetic composition with functions of increasing skin elasticity and anti-wrinkle and its ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/64A61K8/68A61K8/11A61K8/9728A61K8/44A61K8/67A61K8/9789A61K8/92A61Q17/00A61Q19/00
CPCA61K8/11A61K8/44A61K8/64A61K8/645A61K8/67A61K8/68A61K8/922A61K2800/805A61K2800/81A61K2800/85A61Q17/00A61Q19/00A61K8/9728A61K8/9789
Inventor 康立峰吴荣荣
Owner GRF WUHAN BIOTECH
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