Integrated composite multilayer anti-adhesion hemostatic sponge and preparation method thereof

Abstract

The invention discloses an integrated composite multilayer anti-adhesion hemostatic sponge. The sponge specifically comprises an upper surface weaving protective layer, a middle porous hemostatic gellayer and a lower surface porous hemostatic gel weaving composite layer which are sequentially bonded and crosslinked to form an integrated composite multi-layer structure. The upper surface weaving protective layer comprises a middle porous hemostatic gel layer and a lower surface porous hemostatic gel composite layer, wherein the upper surface weaving protective layer is a mesh fabric woven by chitosan fiber and / or bletilla striata polysaccharide fiber. The intermediate porous hemostatic gel layer is chitosan. Polyethylene glycol modified porous gel layer. A low surface porous hemostatic gelwoven composite lay is composed of bletilla striata polysaccharide modified fiber woven cloth and chitosan, wherein that lower surface porou hemostatic gel woven composite layer is composed of bletilla striata polysaccharide modified fiber and chitosan. Polyethylene glycol modified porous gel composite. The whole sponge product has the advantages of high molding degree, quick blood suction and hemostasis, good air permeability, persistent hemostasis and bactericidal resistance to infection, good anti-adhesive effect without additional additives, high biocompatibility, and effectively avoidingthe negative influence of the use and release of other additives in the sponge product on the secondary infection of the wound and the like.

Description

technical field [0001] The invention relates to the field of medical materials, in particular to an anti-adhesion and hemostatic sponge with multiple layers that has good blood-sucking and hemostasis functions, disinfection and anti-inflammation, good skin adhesion, high use comfort and good adhesion resistance . Background technique [0002] Hemostasis is the most basic method in the operation of various departments in the hospital, and plays a considerable role in the success of the operation and the safety of the patient. Anesthesia refers to a state that allows patients to undergo surgery or invasive procedures without pain and discomfort. Generally speaking, anesthesia is a kind of reversible functional inhibition of the central nervous system and / or peripheral nervous system produced by drugs or other methods, which is mainly characterized by loss of sensation, especially pain sensation. Usually, arterial or intravenous injection, puncture catheter placement, extubat...

AI Technical Summary

Problems solved by technology

As far as the existing hemostatic sponge is concerned, the hemostatic effect is slow to take effect, the hemostatic effect is not long enough, and the anti-adhesion effect of the sponge depends on the use of additives such as vaseline and paraffin oil, which is not conducive to the biocompatibility of the sponge itself

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