Method for high-temperature continuous acylation in sucralose production

Abstract

The invention relates to a method for high-temperature continuous acylation in sucralose production. The method comprises the following steps: a, conveying esterification liquid obtained from an esterification reaction to an inlet of an acylation reactor by a pump; b, conveying acetic anhydride to a side inlet of the acylation reactor by a pump, performing an acylation reaction on the esterification liquid and the acetic anhydride in the acylation reactor, wherein the temperature of the reactor is between 25 and 35 DEG C, the mass flow ratio of the esterification liquid to the acetic anhydrideis 10:1 to 15:1, and the pH value after the acylation reaction is 4.5-5.5; and c, conveying a mixed solution after the acylation reaction to an acylation kettle for cooling, and controlling the temperature at 10-15 DEG C. The method provided by the invention has the advantages that an acylation reaction can be continuously realized by a reactor, and full-automatic control is adopted, so that theproduction efficiency is greatly improved, the reaction temperature is increased, the production energy consumption is greatly reduced, the production cost is reduced, and the production reaction yield is improved.

Description

technical field [0001] The invention belongs to the technical field of chemical industry, and in particular relates to a high-temperature continuous acylation method in the production of sucralose. Background technique [0002] Sucralose is a fresh sweetener, its sweetness is 600-800 times that of sucrose, and its sweetness is similar to that of sucrose. Sucralose is not absorbed by the human body, has no bioaccumulation, and has high safety. The sucrose industry developed rapidly, the number of production enterprises gradually increased, and the output continued to increase. The acylation reaction in the production process of sucralose is basically carried out at an acylation temperature of -2 to 2°C, and is carried out intermittently in a reactor, the reaction temperature is low, the reaction is slow, and the operation is intermittent, the reaction conditions are not easy to control, and the yield is low. Moreover, controlling the reaction temperature at -2 to 2°C require...

AI Technical Summary

Problems solved by technology

The acylation reaction in the production process of sucralose is basically carried out at an acylation temperature of -2 to 2°C. It is carried out intermittently in the reactor, the reaction temperature is low, the reaction is slow, and the operation is intermittent, the reaction conditions are not easy to control, and the yield is low.

Moreover, the reaction temperature is controlled at -2~2°C, which needs to be cooled by -15°C frozen brine to ensure the reaction conditions, consume a lot of energy, and the reaction is uneconomical. It is significantly affected by temperature conditions and the reaction yield is low.

This reaction greatly limits the continuous industrial production of the sucralose industry, and most of them are controlled by manual on-site operation, which is greatly influenced by human beings, which is not conducive to the expansion and stability of industrial production.

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