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A Passive Convergent-Divergent Micromixer for Low Diffusion Coefficient Fluids

A micro-mixer and fluid mixing technology, applied in the field of micro-total analysis system, can solve the problems of high energy consumption of active mixer and high complexity of micro-fluidic system, etc.

Active Publication Date: 2021-04-20
DALIAN UNIV OF TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

However, active mixers consume a lot of energy and are complex to integrate with microfluidic systems

Method used

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  • A Passive Convergent-Divergent Micromixer for Low Diffusion Coefficient Fluids
  • A Passive Convergent-Divergent Micromixer for Low Diffusion Coefficient Fluids
  • A Passive Convergent-Divergent Micromixer for Low Diffusion Coefficient Fluids

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Embodiment Construction

[0048] The specific implementation manners of the present invention will be further described below in conjunction with the accompanying drawings and technical solutions.

[0049] The present invention proposes a passive convergent-divergent micro-mixer for fluids with low diffusion coefficient. The mixer is made of polydimethylsiloxane (PDMS). The channel structure pattern is transferred to a single crystal silicon wafer to obtain a positive mold; then the PDMS stock solution and the curing agent are mixed evenly at a ratio of 10:1, and the air bubbles in the PDMS mixed solution are discharged using a vacuum drying oven, and then coated on the mold, and then vacuumed again Remove the air bubbles on the mold, and then heat at a constant temperature of 80°C for two hours; finally, peel off the heated and cured PDMS from the single crystal silicon wafer in absolute ethanol, then clean it with deionized water, and dry it with nitrogen gas for later use. Permanently bond the PDMS ...

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Abstract

The invention belongs to the field of micro-total analysis system, fluid micro-mixing and related fields, and relates to a passive convergent-divergent micro-mixer for low diffusion coefficient fluid. The micro-mixer consists of a fluid inlet channel, a fluid mixing channel, and a fluid outlet channel Composition, and repeated polygonal structural units in the fluid mixing channel, the polygonal structural units are staggered to form a convergent-divergent cavity structure between the toothed sides of the polygonal structural unit and a mixing chamber at the top of the polygonal structural unit body structure. The convergent-divergent cavity structure induces the fluid to undergo periodic changes, forming a convergent-divergent flow change. Through the convergent-divergent effect and the sharp angle effect of the mixing cavity structure, the fluid is induced to produce multiple mechanisms other than the diffusion mechanism in the mixing cavity. a mixing mechanism. The invention can realize rapid and efficient mixing between fluids with low diffusion coefficients in a wide range of Reynolds numbers.

Description

technical field [0001] The invention belongs to the field of micro-total analysis system, micro-fluid mixing and related fields, and relates to a passive convergent-divergent micro-mixer for fluid with low diffusion coefficient. Background technique [0002] With its unique advantages such as miniaturization, integration, and less sample consumption, microfluidic devices are widely used in the fields of biology and chemistry, including biochemical analysis, medical diagnosis, genetic testing, and drug development. At the microscopic scale, the fluid in the microchannel is mainly in the state of laminar flow, and the mixing between the fluids in the natural state depends entirely on the molecular diffusion between the fluid layers with different concentrations. Diffusion mixing itself is a slow and inefficient process, requiring considerable time and sufficiently long channels to achieve effective mixing. According to Fick's law, the total time required for diffusion is inve...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): B01F13/00
CPCB01F33/3017
Inventor 洪昕刘江涛
Owner DALIAN UNIV OF TECH
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