Rat and mouse duodenum-jejunum internal sleeve pipe

Abstract

The invention discloses a rat and mouse duodenum-jejunum internal sleeve pipe, and relates to the field of medical experiment. The rat and mouse duodenum-jejunum internal sleeve pipe comprises a hosehead, a hose body part, an elastic ring, single-ring bending springs and anchor hooks, wherein the single-ring bending springs and the anchor hooks are arranged at the hose head; the diameter of the hose body part is 2-10mm, the length of the hose body part is 50-200mm, and the thickness of the side wall of the hose body part is 0.005mm-0.1mm; the hose head is in the shape of a loudspeaker, a cylinder or a waist drum, the length of the hose head is 3mm-10mm, and the thickness of the side wall of the hose head is 0.005mm-0.1mm; and the hose head comprises the elastic ring which is continuouslysurrounded in a V shape or a trapezoid shape; and the diameter of the elastic ring is 0.05mm-0.1mm. The rat and mouse duodenum-jejunum internal sleeve pipe disclosed by the invention is simple in structure, stable in mechanics, easy to operate and good in biocompatibility and can meet requirements of rats and mice; the rat and mouse duodenum-jejunum internal sleeve pipe can be placed in duodenum-jejunum through an upper gastrointestinal with the assistance of an endoscope, so that a gallbladder and pancreas shunting system is established.

Description

technical field [0001] The invention relates to the field of medical experiments, in particular to a duodenum-jejunum built-in cannula for rats and mice. Background technique [0002] At present, the research on the pathogenesis of type 2 diabetes and the exploration of treatment methods mainly use rats to establish animal models of diabetes. The treatment methods include drug therapy and metabolic surgery, which has become popular in recent years. Low curative effect, poor tolerance and large side effects and other problems, it is difficult to achieve the desired therapeutic effect. Surgical treatment is more effective than medical treatment. Surgical methods mainly include sleeve gastrectomy, gastric bypass surgery, gastric banding, gastric bypass surgery, etc. These surgical methods can often achieve better treatment in a short period of time Therefore, it is widely welcomed, but with the follow-up research reports of many scholars, it is found that these surgical method...

AI Technical Summary

Problems solved by technology

[0002] At present, the research on the pathogenesis of type 2 diabetes and the exploration of treatment methods mainly use rats to establish animal models of diabetes. The treatment methods include drug therapy and metabolic surgery, which has become popular in recent years. Low curative effect, poor tolerance and large side effects, it is difficult to achieve the desired therapeutic effect

Surgical treatment is more effective than medical treatment. Surgical methods mainly include sleeve gastrectomy, gastric bypass surgery, gastric banding, gastric bypass surgery, etc. These surgical methods can often achieve better treatment in a short period of time Therefore, it is widely welcomed, but with the follow-up research reports of many scholars, it is found that these surgical methods are accompanied by many side effects and sequelae risks while achieving good curative effect, such as: risk of general anesthesia, death, anastomotic infection , leakage of intestinal contents, massive bleeding, irreversible nerve damage, intestinal adhesions, etc.

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