Dairy cow nipple disinfection preparation and preparation method thereof

A technology for disinfecting preparations and cow teats, which can be used in antiviral agents, antifungal agents, pharmaceutical formulations, etc., to solve problems such as carcinogenic effects, endocrine dysfunction, and dry teats

Inactive Publication Date: 2019-07-23
ZHENGZHOU BARY ANIMAL PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] At present, the vast majority of large-scale cattle farms in my country have incorporated teat dipping into the feeding and management work. There are many teat dipping products on the market, but most of them are antibiotics, hormones or chemical synthetic drugs. Long-term use of these drugs will cause teats to dry out. Drug-resistant strains increase, endocrine dysfunction, or enter the breast milk to cause harm to the human body, and some even have carcinogenic effects

Method used

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  • Dairy cow nipple disinfection preparation and preparation method thereof

Examples

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Effect test

Embodiment 1

[0023] The present embodiment provides 1000 parts by weight of a milk teat disinfection solution, including the following raw materials by weight: 100 parts of Sophora flavescens, 100 parts of Dandelion, 75 parts of Radix Glycyrrhizae, 50 parts of Dijincao, 20 parts of glycerin, 1 part of benzoic acid, α - 25 parts of pyrrolidone, the balance being water. The preparation method of this milk cow nipple disinfectant comprises the following steps:

[0024] Weigh 100 parts of sophora flavescens, 100 parts of dandelion, 75 parts of licorice, add 8 times the amount of water, heat and reflux for extraction for 1 hour, and filter; add 6 times the amount of water to the filter residue, heat and reflux for 1 hour and filter; combine the two filtrates, Concentrate to a concentrated liquid A with a density of 0.8 g / ml, refrigerate at 4°C, centrifuge at 3500 rpm / min for 20 minutes, and take the supernatant to obtain the centrifugal liquid A;

[0025] Take 50 parts of Dijincao, add 8 times...

Embodiment 2

[0028] The present embodiment provides 1000 parts by weight of a milk teat disinfectant, including the following raw materials by weight: 150 parts of Sophora flavescens, 150 parts of Dandelion, 100 parts of Licorice, 75 parts of Dijincao, 20 parts of glycerin, 2 parts of benzoic acid, tobacco 40 parts of amide, 30 parts of α-pyrrolidone, and the balance is water. The preparation method of this milk cow nipple disinfectant comprises the following steps:

[0029] Weigh 150 parts of sophora flavescens, 150 parts of dandelion, 100 parts of licorice, add 8 times the amount of water, heat and reflux for extraction for 1.5 hours, and filter; add 8 times the amount of water to the filter residue, heat and reflux for 1 hour and filter; combine the two filtrates, Concentrate to a concentrated solution A with a density of 0.9 g / ml, refrigerate at 4°C, centrifuge at 4000 rpm / min for 20 minutes, and take the supernatant to obtain the centrifugal solution A;

[0030] Take 75 parts of Diji...

Embodiment 3

[0033] The present embodiment provides 1000 parts by weight of a milk teat disinfectant, including the following raw materials in parts by weight: 200 parts of Sophora flavescens, 200 parts of Dandelion, 150 parts of Licorice, 100 parts of Dijincao, 20 parts of glycerin, 2 parts of benzoic acid, tobacco 50 parts of amide, 40 parts of α-pyrrolidone, and the balance is water. The preparation method of this milk cow nipple disinfectant comprises the following steps:

[0034] Weigh 200 parts of sophora flavescens, 200 parts of dandelion, 150 parts of licorice, add 10 times the amount of water, heat and reflux for extraction for 1.5 hours, and filter; add 8 times the amount of water to the filter residue, heat and reflux for 1 hour and filter; combine the two filtrates, Concentrate to a concentrated solution A with a density of 1.0 g / ml, refrigerate at 4°C, centrifuge at 4500 rpm / min for 20 minutes, and take the supernatant to obtain the centrifugal solution A;

[0035] Take 100 p...

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Abstract

The invention provides a dairy cow nipple disinfection preparation. The active ingredients mainly consist of the following raw materials in parts by weight: 100-200 parts of lightyellow sophora roots,100-200 parts of dandelions, 50-100 parts of creeping euphorbia and 75-150 parts of liquorice. The invention also provides a preparation method of the dairy cow nipple disinfection preparation. The dairy cow nipple disinfection preparation is simple in preparation method, does not freeze under the environment of minus 5 DEG C, is convenient to use, has moisturizing effect and no irritation to skin, and can treat both symptoms and root causes in the aspect of preventing and treating dairy cow mastitis. Moreover, the product is safe, has no influence on foods, and has no toxic or side effect onlivestock bodies.

Description

technical field [0001] The invention relates to the field of veterinary drugs, in particular to a dairy cow teat disinfection preparation and a preparation method thereof. Background technique [0002] It has been reported that 150 kinds of pathogenic microorganisms were isolated from cow mammary gland tissue, including 14 kinds of bacteria, 2 kinds of mycoplasma, 7 kinds of fungi and viruses, among which Staphylococcus aureus had the highest incidence rate (its isolation rate accounted for 40%- 50%), streptococcus and Escherichia coli. In recent years, the incidence of mastitis caused by mycoplasma and fungi has increased year by year. Mastitis is an inflammatory response of cow mammary gland tissue to external microbial invasion or physical and chemical stimuli. The incidence of dairy cow mastitis in my country is relatively high, and the annual economic loss is as high as hundreds of billions. [0003] In order to prevent mastitis in dairy cows, it is necessary to stren...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/489A61P15/14A61P31/02A61P31/10A61P31/12
CPCA61K36/288A61K36/47A61K36/484A61K36/489A61K2236/331A61K2236/333A61K2236/39A61P15/14A61P31/02A61P31/10A61P31/12A61K2300/00
Inventor 陈长青梁桂霞邓俊丁佳丽刘书洋崔小七
Owner ZHENGZHOU BARY ANIMAL PHARMA
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