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Preparation method of vitamin C oral antibacterial medicine solution and spraying agent prepared through method

An oral and medicinal liquid technology, applied in antibacterial drugs, antifungal agents, pharmaceutical formulations, etc., can solve the problems of human immunity, visceral dysfunction, unfriendly medication process, interpersonal troubles, etc., to enhance human immunity, The effect of remarkable bactericidal effect and excellent drug-friendliness

Inactive Publication Date: 2019-08-09
陕西秦医生优养健康科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Under long-term high-intensity working conditions, human immunity and viscera dysfunction often occur, which in turn causes adverse reactions such as bad breath and oral inflammation, and brings great troubles to interpersonal communication.
In addition, in response to the fast pace of life, all kinds of fast food are also popular among people today, but fast food is mostly salted and smoked food, and the nitrite contained in it will combine with amines in the stomach to produce Therefore, long-term consumption of fast food will bring great health risks to the human body, and it will also cause oral diseases, such as oral infection and throat inflammation.
[0003] Clinically, for oral infectious diseases and throat inflammation, oral antibacterial and anti-inflammatory drugs are mostly used. This kind of treatment method has the problem of low local utilization rate due to systemic administration. In addition, there are certain toxic and side effects and cause physical discomfort
At the same time, oral antibacterial and anti-inflammatory drugs are mostly tablets or capsules, which are not friendly to people with severe oral or throat inflammation and children.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0038] The pretreated medicinal-grade raw materials are taken according to the mass percentage, and a small amount of pure water is added to a container with 41.00% of Octopus, 41.00% of Shandougen, 4.60% of cicada slough, and 6.90% of mulberry leaves (the amount of water exceeds 1- 2cm) for a period of time, then transferred to a temperature-controlled casserole, added pure water to a total volume of 1000mL, boiled for 2 hours, and kept at 60°C for 30 minutes to obtain a solid-liquid mixture. The above-mentioned solid-liquid mixture was boiled again for 1 hour, and the temperature was also kept at 60° C. for 30 minutes. After cooling, the obtained solid-liquid mixture was filtered under reduced pressure to obtain filtrate A. Concentrate the obtained filtrate A in a water bath at 50°C to a clear paste A with a relative density of 1.05-1.10. Then add ethanol to the clear paste A obtained above to make the alcohol content reach 80%. After standing for 24 hours, filter under redu...

Embodiment 2

[0041] According to different capacity specifications prepared in Example 1, it is filled into a special spray bottle under a clean environment to make a vitamin C oral antibacterial spray.

[0042] The above-mentioned capacity specifications can be formulated according to the size of the internal solvent of the special spray bottle. At the same time, considering the shelf life of the drug and the possible dosage during the shelf life, the following specifications can generally be selected: 10mL, 15mL, 20mL, 25mL, 30mL.

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PUM

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Abstract

The invention relates to a preparation method of a vitamin C oral antibacterial medicine solution and a spraying agent prepared through the method. Through processes of soaking, two-time decoction, heat-preservation leaching and ethyl alcohol extraction, effective components in ardisia crenata sims, vietnamese sophora roots, periostracum cicada and mulberry leaves are sufficiently extracted and refined, and with assistance of auxiliary materials such as vitamin C and menthol, the vitamin C oral antibacterial medicine solution is prepared. The medicine solution of a composition with traditionalChinese medicine raw materials has dual functions, has an obvious sterilization effect on escherichia coli, candida albicans, staphylococcus aureus and oral cancer cells, is safe and free of toxic orside effect, and has an obvious function of solving an oral odor problem caused by immunity elimination and viscera function imbalance. Meanwhile, the medicine solution is stable in performance, suitable for being subjected to filling and prepared into the spraying agent and convenient to carry and use, and the medicine application experience of children and critical patients with oral cavity andthroat inflammation can be improved.

Description

technical field [0001] The invention relates to the technical field of daily oral cavity antibacterial cleaning, in particular to a preparation method of vitamin C oral antibacterial liquid and a spray thereof. Background technique [0002] With the rapid development of science and technology, the pace of life is accelerating and communication is more frequent. At the same time, the intensity of work and working hours have also increased significantly. In this state, people are paying more and more attention to personal image and health care. Under long-term high-intensity working conditions, human immunity and organ dysfunction often occur, which in turn causes adverse reactions such as bad breath and oral inflammation, and brings great troubles to interpersonal communication. In addition, in response to the fast pace of life, all kinds of fast food are also popular among people today, but fast food is mostly salted and smoked food, and the nitrite contained in it will comb...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/605A61K9/12A61K47/12A61P1/02A61P31/04A61P31/10A61K31/375A61K35/64
CPCA61K9/006A61K9/12A61K31/375A61K35/64A61K36/185A61K36/489A61K36/605A61K47/12A61K2236/331A61K2236/55A61P1/02A61P31/04A61P31/10A61K2300/00Y02A50/30
Inventor 张珈凯王杰
Owner 陕西秦医生优养健康科技有限公司