Glyceride mixture rich in polyunsaturated fatty acids and preparation method and applications thereof

A technology of unsaturated fatty acids and mixtures, which is applied in the field of glyceride mixtures rich in polyunsaturated fatty acids and its preparation and application, can solve the problems of unsatisfactory and unstable health care effects, achieve the effect of reducing blood fat and weight loss, reduce Blood pressure and blood lipid lowering effect

Pending Publication Date: 2019-08-20
SERICULTURE & AGRI FOOD RES INST GUANGDONG ACAD OF AGRI SCI
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] In view of the unsatisfactory and unstable health care effects of existing PUFA products such as blood fat reduction and weight loss, the purpose of the present invention is to provide a polyunsaturated fatty acid oil composition with high PUFA absorption rate and efficient blood fat reduction and weight loss functions

Method used

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  • Glyceride mixture rich in polyunsaturated fatty acids and preparation method and applications thereof
  • Glyceride mixture rich in polyunsaturated fatty acids and preparation method and applications thereof
  • Glyceride mixture rich in polyunsaturated fatty acids and preparation method and applications thereof

Examples

Experimental program
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Effect test

Embodiment 1

[0022] Commercially available fish oil fatty acid, algal oil fatty acid, linolenic acid, conjugated linoleic acid are used as raw materials, mixed in a certain proportion (PUFA composition is CLA 10.85%, ALA 5.41%, GLA 3.22%, CNLA 1.04%, AA 10.28%, EPA30 .15%, DPA 3.14%, DHA 31.17%). Utilize partial glyceride lipase Lipase G50 (derived from penicilliumcamembertii, purchased from Amano Enzyme Co., Ltd., Japan) to catalyze the reaction of fatty acid and glycerol to synthesize a mixture containing diglyceride and monoglyceride, the amount of lipase added is 1%, and the amount of water added 0.5%. After 12 hours of esterification reaction, the mixture was centrifuged, and the upper oil phase was recovered, and the fatty acid in it was separated and removed by molecular distillation to obtain a product mainly composed of glyceride. The content of diglyceride in the product after molecular distillation is 51.5%, the content of monoglyceride is 46.0%, the content of triglyceride is ...

Embodiment 2

[0024] Commercially available fish oil fatty acid, conjugated linoleic acid, linolenic acid, and pomegranate seed oil fatty acid are used as raw materials and mixed in a certain proportion (PUFA composition is CLA 3.24%, ALA 6.01%, GLA 1.65%, CNLA 37.55%, AA 1.31%, EPA20.75%, DPA 2.42%, DHA 21.42%). A mixture containing diglyceride and monoglyceride was synthesized by using partial glyceride lipase Lipase G50 to catalyze the reaction of fatty acid and glycerol. The added amount of lipase was 1%, and the added amount of water was 0.5%. After 12 hours of esterification reaction, the mixture was centrifuged, and the upper oil phase was recovered, and the fatty acid in it was separated and removed by molecular distillation to obtain a product mainly composed of glyceride. The content of diglyceride in the product after molecular distillation is 54.3%, the content of monoglyceride is 42.7%, the content of triglyceride is 2.2%, and the content of free fatty acid is 0.7%. The total ...

Embodiment 3

[0026] Commercially available fish oil fatty acid, conjugated linoleic acid, linolenic acid, and pomegranate seed oil fatty acid are used as raw materials and mixed in a certain proportion (PUFA composition is CLA 3.58%, ALA 5.94%, GLA 1.58%, CNLA 37.16%, AA 1.27%, EPA20.53%, DPA 2.37%, DHA 21.83%). A mixture containing diglyceride and monoglyceride was synthesized by using partial glyceride lipase Lipase G50 to catalyze the reaction of fatty acid and glycerol. The added amount of lipase was 1%, and the added amount of water was 0.5%. After 12 hours of esterification reaction, the mixture was centrifuged, and the upper oil phase was recovered, and the fatty acid in it was separated and removed by molecular distillation to obtain a product mainly composed of glyceride. The content of diglyceride in the product after molecular distillation is 88.3%, the content of monoglyceride is 10.4%, the content of triglyceride is 1.2%, and the content of free fatty acid is 0.1%. The total ...

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Abstract

The invention discloses a glyceride mixture rich in polyunsaturated fatty acids and a preparation method and applications thereof. The mixture comprises 95% or above by weight of glycerides and 5% orbelow by weight of free fatty acids. The content of diglyceride in the glycerides is 30-98wt%, the content of monoglyceride is 0.1-70wt%, and the content of triglyceride is 0-5wt%. The composition consists of polyunsaturated fatty acids including the monoglyceride and the diglyceride with a certain concentration according to a certain proportion, improves the absorption rate of the polyunsaturatedfatty acids, has more efficient effects of reducing blood fat and losing weight, and can be applied to the preparation of medicines or health-care products for losing weight and reducing blood fat.

Description

technical field [0001] The present invention is that the glyceride composition rich in unsaturated fatty acid has more efficient absorption rate, lowering blood fat and slimming effect. Background technique [0002] With the rapid development of social economy, the improvement of people's living standards, the pace of life is also accelerating, people's dietary structure has undergone tremendous changes, high-fat and high-sugar fast food dietary structure has increasingly occupied the vast majority of the market. This has led to abnormal lipid metabolism in many countries in the world, and the morbidity and mortality of hyperlipidemia and obesity have also increased, seriously affecting human health. Carrying out the research and development of dietary supplements with weight-loss and lipid-lowering functions conforms to the trend of social development and has a good application prospect. At present, the dietary supplement products for obesity and hyperlipidemia on the mark...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/232A61P3/04A61P3/06A23L33/12
CPCA61K31/232A61P3/04A61P3/06A23L33/12A23V2002/00A61K2300/00A23V2200/332A23V2250/186
Inventor 王卫飞廖森泰邹宇晓穆利霞王思远胡腾根
Owner SERICULTURE & AGRI FOOD RES INST GUANGDONG ACAD OF AGRI SCI
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