Unlock instant, AI-driven research and patent intelligence for your innovation.

Release agent for hollow hard capsule and preparing method thereof

A technology of hollow hard capsules and release agents, which is applied in the field of release agents for hollow hard capsules and its preparation, can solve the problems of physical and mental health effects, poor antibacterial properties of release agents, and difficult cleaning of molds, so as to ensure safety and assembly Easy to divide and improve the effect of antibacterial properties

Active Publication Date: 2019-08-23
JIANGSU LEFAN CAPSULE
View PDF3 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] There are many kinds of existing release agents, most of which use oil as the active ingredient, but the application of a large amount of oil will result in poor antibacterial properties of the release agent, and it is difficult to clean the mold after production. In addition, because oils are easy to breed bacteria, in order to Prolonging the quality of hollow capsules and choosing preservatives will also affect human physical and mental health

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0018] A release agent for hollow hard capsules, which is composed of purified water, carnauba wax, starch and sodium lauryl sulfate. The above components are 500 parts by weight of purified water, 15 parts of carnauba wax, 20 parts of corn starch and 1 part of sodium lauryl sulfate.

[0019] The above-mentioned preparation method of a release agent for hollow hard capsules includes the following steps:

[0020] Step 1. Weigh purified water, carnauba wax, starch and sodium lauryl sulfate in parts by weight;

[0021] Step 2. Mix sodium lauryl sulfate with purified water, add starch, heat to 35°C at a heating rate of 1°C / min, stir evenly at 150rpm, then add carnauba wax, and set the heating rate at 1.5 atm. Heat to 70°C at 5°C / min, continue to stir, and when it is naturally cooled to 40°C, filter to obtain the release agent.

[0022] The release agent of Example 1 was used in the production of gelatin hard hollow capsules. According to the national standard test, the release of the rel...

Embodiment 2

[0024] A release agent for hollow hard capsules, which is composed of purified water, carnauba wax, corn starch and sodium lauryl sulfate. The above components are 508 parts by weight of purified water and 17 parts of carnauba wax by weight. , 23 parts of corn starch, 2 parts of sodium lauryl sulfate.

[0025] The above-mentioned preparation method of a release agent for hollow hard capsules includes the following steps:

[0026] Step 1. Weigh purified water, carnauba wax, starch and sodium lauryl sulfate in parts by weight;

[0027] Step 2. Mix sodium lauryl sulfate with purified water, add starch, heat to 38°C at a heating rate of 1.8°C / min, stir evenly at 178 rpm, and then add carnauba wax. At 2 atmospheres, the heating rate is , Heat to 75℃ at 8℃ / min, continue to stir, when it is naturally cooled to 40℃, filter, then release agent is obtained.

[0028] The release agent of Example 2 is used in the production of gelatin hard hollow capsules. According to the national standard test...

Embodiment 3

[0030] A release agent for hollow hard capsules, which is composed of purified water, carnauba wax, corn starch and sodium lauryl sulfate. The above components are 510 parts of purified water and 20 parts of carnauba wax in parts by weight. , 25 parts of corn starch, 3 parts of sodium lauryl sulfate.

[0031] The above-mentioned preparation method of a release agent for hollow hard capsules includes the following steps:

[0032] Step 1. Weigh purified water, carnauba wax, starch and sodium lauryl sulfate in parts by weight;

[0033] Step 2: Mix sodium lauryl sulfate with purified water, add starch, heat at a rate of 2°C / min to 40°C, stir evenly at 200 rpm, and add carnauba wax, and the temperature rise rate is 12°C at 2 atmospheres / min heat to 80℃, continue to stir, when it is naturally cooled to 40℃, filter, then release agent.

[0034] The release agent of Example 3 is used in the production of gelatin hard hollow capsules. According to the national standard test, the release of t...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention discloses a release agent for a hollow hard capsule and a preparing method thereof. The release agent consists of the following components in parts by weight: 500-510 parts of purified water, 15-20 parts of carnauba wax, 20-25 parts of starch and 1-3 parts of lauryl sodium sulfate. The preparing method comprises the following steps: mixing the lauryl sodium sulfate and the purified water, adding the starch, heating below 35-40 DEG C, stirring uniformly, then adding the carnauba wax, heating to 70-80DEG C under 1.5-2 barometric pressure, continuously stirring, carrying out filtering when the mixture is naturally cooled to 40DEG C, and obtaining the release agent. Compared with the prior art, the release agent has the advantages that the components are simple, the adding of grease is reduced on the basis of ensuring a release effect, and the safety of the release agent is ensured; and as the adding of the nutritive grease is reduced, the anti-bacterial property of the release agent is improved without adding a preservative.

Description

Technical field [0001] The invention belongs to the technical field of hard capsule preparation, in particular to a release agent for hollow hard capsules and a preparation method thereof. Background technique [0002] Capsules are used as a dosage form for solid, semi-solid, liquid, pill or herbal preparations to provide a good disintegration star after administration, ensure that the active substance passes through the intestines and stomach, and reduce dissolution waste. At present, hollow capsules use gelatin extracted from beef bones or pig skin as the main raw material. Gelatin has very good properties when preparing capsules. For the production of hollow capsules, considering that the quality of the release of the capsule after molding directly affects the pass rate of the product, a release agent is chosen. [0003] There are many types of existing release agents, most of which use fats and oils as active ingredients. However, the application of a large amount of fats and...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): B29C33/62
CPCB29C33/62
Inventor 方忠明王飞陈思宇潘恒褚志伟
Owner JIANGSU LEFAN CAPSULE