Anti-allergic rhinitis gel

An anti-allergy and rhinitis technology, which is applied in the direction of allergic diseases, medical preparations with non-active ingredients, respiratory diseases, etc., can solve the problems of dependence, drowsiness, side effects, and short action time, so as to improve cleanliness and cost Inexpensive, avoid direct contact effect

Active Publication Date: 2019-09-27
ZHENGZHOU KANG JINRUI HEALTH PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Although antiallergic drugs have good effects on nasal itching, sneezing, and runny nose, they have relatively short action time and side effects of drowsiness after taking the drug, and rebound

Method used

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  • Anti-allergic rhinitis gel

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0019] An antiallergic rhinitis gel, made of the following materials in parts by weight: 40 parts by weight of isomaltooligosaccharide, 1.6 parts by weight of thymol, 8 parts by weight of glycerin, 3.2 parts by weight of carbomer, 1.2 parts by weight of disodium edetate parts by weight, 0.3 parts by weight of sodium hydroxide, 5 parts by weight of polysorbate-80, and 50 parts by weight of water.

[0020] The preparation method of the anti-allergic rhinitis gel comprises the following steps: adding isomalto-oligosaccharide to water at 50° C. and stirring for 30 minutes, then adding thymol, glycerin and carbomer and continuing stirring for 90 minutes to obtain a reaction system, and then adding a hydroxide Adjust the pH of the reaction system with sodium to 6.5-7.2, then add disodium edetate and polysorbate, and stir evenly to obtain the anti-allergic rhinitis gel.

Embodiment 2

[0022] An antiallergic rhinitis gel, made of the following materials in parts by weight: 30 parts by weight of isomaltooligosaccharide, 0.5 parts by weight of thymol, 12 parts by weight of glycerin, 8 parts by weight of carbomer, 2 parts by weight of disodium edetate parts by weight, 0.2 parts by weight of sodium hydroxide, 3 parts by weight of polysorbate-80, and 50 parts by weight of water.

[0023] The preparation method of the anti-allergic rhinitis gel comprises the following steps: adding isomaltose oligosaccharide to water at 60°C and stirring for 60 minutes, then adding thymol, glycerin and carbomer and continuing to stir for 60 minutes to obtain a reaction system, and then adding hydroxide Adjust the pH of the reaction system with sodium to 6.5-7.2, then add disodium edetate and polysorbate, and stir evenly to obtain the anti-allergic rhinitis gel.

Embodiment 3

[0025] An antiallergic rhinitis gel, made of the following materials in parts by weight: 50 parts by weight of isomaltooligosaccharide, 1 part by weight of thymol, 20 parts by weight of glycerin, 10 parts by weight of carbomer, 1.2 parts by weight of disodium edetate parts by weight, 0.2 parts by weight of sodium hydroxide, 6 parts by weight of polysorbate-80, and 50 parts by weight of water.

[0026] The preparation method of the anti-allergic rhinitis gel comprises the following steps: adding isomalto-oligosaccharide to water at 45°C and stirring for 30 minutes, then adding thymol, glycerin and carbomer and continuing to stir for 100 minutes to obtain a reaction system, and then adding hydroxide Adjust the pH of the reaction system with sodium to 6.5-7.2, then add disodium edetate and polysorbate, and stir evenly to obtain the anti-allergic rhinitis gel.

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Abstract

The invention relates to relates to technical fields of anti-allergic rhinitis gel and the preparation thereof, in particular to anti-allergic rhinitis gel. The anti-allergic rhinitis gel is prepared from the following materials in parts by weight: 20 to 60 parts of Isomaltooligosaccharide, 0.2 to 2 parts of thymol crystals, 6 to 20 parts of glycerinum, 3.2 to 15 parts of carbopol, 1 to 3 parts of disodium edentate, 0.1 to 0.5 part of sodium hydroxide, 1 to 8 parts of polysorbate-80, and 50 parts of water. The anti-allergic rhinitis gel can obstruct allergen, and prevent nasal mucosa from being in direct contact with the allergen, thereby producing an antiallergic effect. The anti-allergic rhinitis gel does not contain medicine compositions, so that the anti-allergic rhinitis gel cannot produce dependency and rebound phenomenon, does not have any toxic and/or side effects, and has the characteristics of high application range and low cost.

Description

technical field [0001] The invention relates to the technical field of anti-allergic rhinitis gel and its preparation, in particular to an anti-allergic rhinitis gel. Background technique [0002] Allergic rhinitis is an allergic inflammatory disease caused by a variety of allergens. It is prone to attack in spring and autumn and in cold climates. It is an allergic reaction that often occurs in the nasal mucosa. The incidence rate has increased in recent years. This disease can occur in men and women of any age, more common with 15-40 years old. Typical symptoms are nasal itching, nasal congestion, sneezing, a large amount of watery nasal discharge, and decreased sense of smell. When allergic rhinitis attacks, the patient is very painful and needs active treatment to relieve symptoms. For allergic rhinitis, we must first pay attention to remove the cause and incentives, such as keeping warm and cold, avoiding contact with pollen, preventing dust mite bites, etc.; secondly,...

Claims

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Application Information

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IPC IPC(8): A61K9/06A61K31/702A61K31/05A61K31/047A61K31/78A61P11/02A61P37/08
CPCA61K9/06A61K47/26A61K31/702A61K31/05A61K31/047A61K31/78A61P11/02A61P37/08A61K2300/00
Inventor 张永红
Owner ZHENGZHOU KANG JINRUI HEALTH PHARMA CO LTD
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