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Mouth wash with function of resisting helicobacter pylori

An anti-Helicobacter pylori and mouthwash technology, applied in the directions of antibacterial drugs, oral care, medical science, etc., can solve the problems of mouthwashes that are not aimed at preventing and reducing oral infection of Helicobacter pylori, etc., and achieves less side effects and drug resistance. small effect

Inactive Publication Date: 2019-10-22
石家庄市中医院
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, the mouthwash sold in pharmacies, clinics or hospitals has the main functions of anti-inflammation, fresh breath, cleans the mouth, and prevents periodontal disease. There is no mouthwash for the prevention and reduction of Helicobacter pylori oral infection

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0069] The invention provides a mouthwash with anti-helicobacter pylori efficacy, which comprises the following components by weight,

[0070] A Chinese medicine active ingredient:

[0071] 0.064 parts of emodin extract;

[0072] 0.064 parts of berberine extract;

[0073] 0.128 parts of matrine extract;

[0074] 0.256 parts of baicalin extract;

[0075] 0.4 parts of mango ginger joint phenol extract;

[0076] B filler:

[0077] Vitamin C 1.2 parts;

[0078] 10 parts of tea polyphenols;

[0079] C flavoring agent:

[0080] 0.5 parts of citric acid;

[0081] 1 part peppermint oil;

[0082] Stevia 0.5 parts;

[0083] 10 parts of sodium chloride;

[0084] D solvent:

[0085] 100 parts of ethanol with a mass fraction of 50%;

[0086] 100 parts of glycerin;

[0087] 766.243 parts of deionized water.

[0088] The purity of the tea polyphenols is higher than 80%.

[0089] The mass fraction of emodin in the described emodin extract is greater than 70%, the mass fraction o...

Embodiment 2

[0133] The invention provides a mouthwash with anti-helicobacter pylori efficacy, which comprises the following components by weight,

[0134] A Chinese medicine active ingredient:

[0135] 0.05 parts of emodin extract;

[0136] 0.1 parts of berberine extract;

[0137] 0.1 parts of matrine extract;

[0138] 0.4 parts of baicalin extract;

[0139] 0.3 part of mango ginger joint phenol extract;

[0140] B filler:

[0141] Vitamin C 1 part;

[0142] 15 parts of tea polyphenols;

[0143] C flavoring agent:

[0144] 0.4 parts of citric acid;

[0145] 0.5 parts of peppermint oil;

[0146] Stevia 0.7 parts;

[0147] 5 parts of sodium chloride;

[0148] D solvent:

[0149] Mass fraction is 50 parts of ethanol of 50%;

[0150] 80 parts of glycerin;

[0151] 500 parts of deionized water.

[0152] The purity of the tea polyphenols is higher than 80%.

[0153] The mass fraction of emodin in the described emodin extract is greater than 70%, the mass fraction of berberine in...

Embodiment 3

[0156] The invention provides a mouthwash with anti-helicobacter pylori efficacy, which comprises the following components by weight,

[0157] A Chinese medicine active ingredient:

[0158] 0.1 parts of emodin extract;

[0159] 0.05 parts of berberine extract;

[0160] 0.2 parts of matrine extract;

[0161] 0.2 parts of baicalin extract;

[0162] 0.7 part of mango ginger joint phenol extract;

[0163] B filler:

[0164] Vitamin C 1.5 parts;

[0165] 20 parts of tea polyphenols;

[0166] C flavoring agent:

[0167] 0.3 parts of citric acid;

[0168] 0.8 parts of peppermint oil;

[0169] Stevia 0.3 part;

[0170] 15 parts of sodium chloride;

[0171] D solvent:

[0172] Mass fraction is 80 parts of ethanol of 50%;

[0173] 50 parts of glycerin;

[0174] 300 parts of deionized water.

[0175] The purity of the tea polyphenols is higher than 80%.

[0176] The mass fraction of emodin in the described emodin extract is greater than 70%, the mass fraction of berberine...

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Abstract

The invention relates to a mouth wash with a function of resisting helicobacter pylori. The mouth wash is prepared from traditional Chinese medicine active components A, a filler B, a corrigent C anda solvent D, wherein the traditional Chinese medicine active components A comprise 0.05-0.1 part of rheum emodin extraction liquid, 0.05-0.1 part of berberine extraction liquid, 0.1-0.2 part of sophocarpidine extraction liquid, 0.2-0.4 part of baicalin extraction liquid and 0.3-0.7 part of mango ginger combined phenol extraction liquid. The mouth wash can effectively kill the helicobacter pylori and inhibit colonization of the helicobacter pylori.

Description

technical field [0001] The invention belongs to the technical field of oral health care and relates to a mouthwash, in particular to a mouthwash with anti-helicobacter pylori effect. Background technique [0002] HP infection is Helicobacter pylori infection. Helicobacter pylori is a Gram-negative bacillus transmitted through oral-oral and fecal-oral transmission. It is closely related to gastric ulcer, chronic gastritis, gastric cancer and other digestive system diseases. The infection rate of Helicobacter pylori in most countries in the world is at a relatively high level. According to the survey, the positive rate of H. the presence of bacteria. At present, the mouthwash sold in pharmacies, clinics or hospitals has the main functions of anti-inflammation, fresh breath, oral cavity cleaning, and prevention of periodontal disease. There is no mouthwash for preventing and reducing Helicobacter pylori oral infection. Contents of the invention [0003] The object of the pr...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/34A61K8/49A61K8/60A61K8/67A61K8/9789A61K8/9794A61Q11/00A61P31/04
CPCA61K8/347A61K8/4926A61K8/4973A61K8/498A61K8/602A61K8/676A61Q11/00A61K8/9789A61K8/9794A61P31/04
Inventor 赵玉斌王津彭安堂吕一豪郭嘉璇师晓阳
Owner 石家庄市中医院
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