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Biotissue transdermal patch

A technology of biological tissue and patch, applied in the direction of drug delivery, treatment, pharmaceutical formulation, etc., can solve problems such as use, and achieve the effect of inhibiting self-discharge

Pending Publication Date: 2019-11-05
NIPPON TELEGRAPH & TELEPHONE CORP
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, for a power supply device using a common dry battery, the dry battery and the power supply device use hazardous materials, rare metals, etc., so there are problems such as reduction of environmental load and simplification of disposal.

Method used

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  • Biotissue transdermal patch
  • Biotissue transdermal patch
  • Biotissue transdermal patch

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0158] Figure 10 It is an exploded perspective view of the battery unit 2 of Embodiment 1, Figure 11 It is a cross-sectional view of the battery unit 2 of the first embodiment.

[0159] The battery unit 2 of Example 1 includes a positive electrode 201 , a negative electrode 202 , a separator 203 , and a conductive layer 204 . In Example 1, carbonized cellulose produced by bacteria was used for the positive electrode 201 . Hereinafter, the preparation of the battery unit 2 of Example 1 will be described.

[0160] The bacteria-generated carbonized cellulose used for the positive electrode 201 was obtained by the following method.

[0161] Coconut fruit (manufactured by Fujicco) is a bacterial cellulose gel produced by Acetobacter xylinum, which belongs to acetic acid bacteria. This coco fruit is used as the gel produced by the bacteria, and the gel produced by the bacteria is placed on the foam plastic It was immersed in liquid nitrogen for 30 minutes in a prepared box and...

Embodiment 2

[0189] Figure 18 It is an exploded perspective view of the battery unit 2 of Embodiment 2, Figure 19 It is a sectional view of the battery unit 2 of the second embodiment.

[0190] Example 2 is different from Example 1 in that it includes a positive electrode separator 203A and a negative electrode separator 203B which are separately arranged. The separator 203 of Example 1 was cut into two rectangular pieces of 30 mm×20 mm by a punching blade, a laser cutter, etc., to form a positive electrode separator 203A and a negative electrode separator 203B.

[0191] The production method, experimental equipment, and evaluation method of the biological tissue patch 1 are the same as those in Example 1.

[0192] Depend on Figure 17 From the measurement results shown, in Example 2, compared with Example 1 and Comparative Example 1, the accumulated permeation amount of L-ascorbic acid at each time was increased. In Example 1, not only biological tissues but also ions moved through ...

Embodiment 3

[0194] Figure 20 It is an exploded perspective view of the battery unit 2 of Embodiment 3, Figure 21 It is a cross-sectional view of the battery unit 2 of Example 3.

[0195] Example 3 is different from Example 2 in that the conductive layer 204 is laminated with a plastic film. Specifically, a polyethylene film (manufactured by Thermo Co., Ltd.) was cut into two pieces of rectangles of 34 mm×54 mm by a punching blade, a laser cutter, etc., one of which was used as the upper surface water-repellent layer 205A, and the other was used as the contact surface. Water repellent layer 205B. For the polyethylene film of the contact surface water-repellent layer 205B, a circular contact portion 205C with a diameter of 10 mm was provided using a punching blade, a laser cutter, or the like so that the positive electrode 201 and the negative electrode 202 were in contact with the conductive layer 204 . The conductive layer 204 is sandwiched between the upper surface water-repellent l...

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Abstract

A biotissue transdermal patch 1 houses a battery part 2 and an active ingredient 3 so as to prevent contact therebetween, causes the battery reaction to begin in the battery part 2 when the biotissuetransdermal patch 1 is in use by effecting contact between the battery part 2 and active ingredient 3, and adheres the battery part 2 to biotissue. Either carbonized bacterial cellulose or cellulose-derived carbon nanofibers are used in a positive terminal 201 of the battery part 2.

Description

technical field [0001] The present invention relates to a biological tissue patch which is attached to biological tissue and allows active ingredients to penetrate into the biological tissue through a weak current, and a battery included in the biological tissue patch. Background technique [0002] Liquid and cream-type cosmetics and pharmaceuticals are widely available to the general public. Attention is being paid to the method of infiltrating active ingredients of cosmetics and pharmaceuticals into the living body through a weak current. It is known that the method using a weak current can be expected to enhance cell activation and drug penetration, but requires an expensive and large-scale power supply device. [0003] In order to solve such a problem, there is known a biological tissue patch provided with a power supply unit using a common dry battery. However, for a power supply device using a common dry battery, since the dry battery and the power supply device use ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61N1/30
CPCA61N1/30A61N1/0428A61N1/0432A61N1/0448A61K9/0009A61K9/7084Y02E60/10
Inventor 野原正也岩田三佳誉林政彦小松武志
Owner NIPPON TELEGRAPH & TELEPHONE CORP
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