Check patentability & draft patents in minutes with Patsnap Eureka AI!

Application of functional magnetic resonance imaging technology fMRI in analysis of human brain area activity changes

A human brain and imaging technology, applied in the field of functional magnetic resonance imaging, can solve the problems of difficult clinical diagnosis and treatment of RP disease, unclear brain function regulation mechanism, etc., and achieve the effect of important clinical application value.

Inactive Publication Date: 2019-12-10
WUHAN UNIV
View PDF2 Cites 7 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the regulatory mechanism of visual loss on brain function in RP patients is still unclear, and there are few neuroimaging studies on the effect of peripheral vision loss on synchronous brain activity, which brings difficulties to the clinical diagnosis and treatment of RP diseases

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Application of functional magnetic resonance imaging technology fMRI in analysis of human brain area activity changes
  • Application of functional magnetic resonance imaging technology fMRI in analysis of human brain area activity changes
  • Application of functional magnetic resonance imaging technology fMRI in analysis of human brain area activity changes

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0034] Example 1 The clinical diagnosis and course evaluation of retinitis pigmentosa (RP) were performed using functional magnetic resonance imaging (fMRI).

[0035] 1. Establishment of fMRI image database for RP patients

[0036] 1. Establish inclusion and exclusion criteria for RP patients

[0037] RP inclusion criteria:

[0038] a) MRI scans can be performed (such as no pacemaker or metal devices implanted in the body, etc.);

[0039] b) No claustrophobia;

[0040] c) No heart disease, high blood pressure and encephalopathy;

[0041] d) clinical features of night blindness;

[0042] e) Thin retinal pigment epithelium and spicule-like pigmentation;

[0043] f) Visual field: Peripheral visual field loss.

[0044] RP exclusion criteria:

[0045] a) RP patients are blind in both eyes;

[0046] b) RP patients are accompanied by eye-related complications (such as cataract, glaucoma, macular edema, etc.);

[0047] c) RP patients with a history of eye surgery.

[0048] 2...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention relates to application of a functional magnetic resonance imaging technology fMRI in analysis of human brain area activity changes. The method comprises the steps of establishing a humanbrain fMRI image database and processing and analyzing obtained image data, wherein the processing and analyzing process of the image data comprises BOLD signal preprocessing, ALFF and fALFF method data analysis, ReHo method data analysis and seed point function analysis. The method can provide iconography basis for clinical diagnosis, course progress evaluation and drug curative effect monitoring of RP, provides important reference basis and technical support for revealing pathogenesis of RP diseases and guiding clinical treatment, and has important clinical application value.

Description

technical field [0001] The present invention relates to the field of functional magnetic resonance imaging (fMRI). Specifically, it mainly uses resting state fMRI technology and local consistency (ReHo) and low frequency amplitude (ALFF) data processing methods to analyze changes in human brain area activity. Background technique [0002] Retinitis pigmentosa (RP) is a blinding hereditary eye disease for which there is no effective treatment, which seriously threatens public health. The clinical treatment of RP is a major problem in the field of ophthalmology. The average incidence rate of typical RP around the world is about 1 / 3500, and about 1.5 million people in the world suffer from this disease. Clinically, retinitis pigmentosa can be manifested as night blindness and progressive loss of visual field. Eye examination can reveal fundus retinal pigmentation, tubular visual field, and electroretinogram peak prolongation, amplitude decrease or even no waveform. Decreased ...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): G06T7/00G06T5/00
CPCG06T7/0012G06T2207/30016G06T2207/10088G06T5/70
Inventor 沈吟黄歆童妍邓琴琴雷新兰李莹
Owner WUHAN UNIV
Features
  • R&D
  • Intellectual Property
  • Life Sciences
  • Materials
  • Tech Scout
Why Patsnap Eureka
  • Unparalleled Data Quality
  • Higher Quality Content
  • 60% Fewer Hallucinations
Social media
Patsnap Eureka Blog
Learn More

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2025 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com