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Herbo-mineral formulation for prevention, treatment and management of diabetes and method of preparation thereof

A diabetes and mineral technology, applied in the direction of drug combination, pharmaceutical formula, non-living material medical raw materials, etc., can solve the problems of controversial effectiveness

Inactive Publication Date: 2019-12-27
MUNIYAL AYURVEDIC RES CENT
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although Ayurvedic treatments have many benefits, the effectiveness of most Ayurvedic herbal preparations is controversial

Method used

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  • Herbo-mineral formulation for prevention, treatment and management of diabetes and method of preparation thereof
  • Herbo-mineral formulation for prevention, treatment and management of diabetes and method of preparation thereof
  • Herbo-mineral formulation for prevention, treatment and management of diabetes and method of preparation thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0107] Embodiment 1: experimental research

[0108] The purpose of this study was to analyze the effects of the test product on pancreatic blood glucose, lipids, histone, pancreatic amylase and islet cells in alloxan-induced diabetic rats.

[0109] Experiment details:

[0110] Animals: Albino rats of either sex, Wistar strain, were fed standard rat pellets and water ad libitum.

[0111] Experimental diabetes: Diabetes was induced by a single intraperitoneal injection of 5% alloxan monohydrate dissolved in 0.9% saline at a dose of 200 mg / kg body weight after a 16-hour fast.

[0112] Test Drug Treatment: Tablets were crushed, weighed and mixed with water to form a homogeneous suspension, administered orally every morning using a gastric tube.

[0113] Dose: 1ml (30mg / cc)

[0114] result:

[0115] image 3 Shown are the results of oral glucose tolerance tests in normal and diabetic rats after test product treatment. Treated normal rats showed a hypoglycemic effect, whil...

Embodiment 2

[0123] Embodiment 2: clinical research

[0124] The purpose of this clinical study is to evaluate the clinical efficacy and safety (long and short term) of the test product as monotherapy and as an adjunct to other oral hypoglycemic agents in the management of NIDDM. The study helps evaluate the effect of the test product on the clinical and biochemical characteristics of diabetic patients.

[0125] Study design: This is a prospective, open label, nonrandomized, phase III clinical trial conducted at the Out Patient Department, Muniyal Ayurvedic Hospital and Research Center, Manipal, India.

[0126] Materials and methods

[0127] Inclusion criteria: A total of 340 sexes, patients diagnosed with NIDDM between the ages of 30 and 60, and patients willing to give informed consent were included in this study. The WHO diagnostic criteria (1980) are considered for the diagnosis of NIDDM (for newly diagnosed patients: FBSL >120 mg%, and after consuming 75 g of glucose 2 hours: >180 m...

Embodiment 3

[0144] Example 3: Quality of Life Study

[0145] Study Design: Prospective observational study design Data Sources:

[0146] Main data: Patient case records and interviews with patients. Secondary data: Internet sites, Ayurveda textbooks, periodicals.

[0147] standard constrain:

[0148] all type 2 diabetics

[0149] Age 18-75

[0150] Diabetics taking only test product tablets

[0151] Patients who agree to sign the ICF

[0152] Patients whose treatment pattern does not change up to 3 months

[0153] Exclusion criteria:

[0154] Type I diabetics.

[0155] pregnant lady.

[0156] lactating women.

[0157] chronically ill patients.

[0158] Patients undergoing lifestyle changes or diet therapy (prediabetic patients).

[0159] Patients who refused to participate in the study.

[0160] Study setting: This study was conducted in a group of patients who received tablets of the test product for the treatment of type II diabetes in and around Udupi and Manipal distric...

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Abstract

Herbo-mineral formulation for prevention, treatment and management of Diabetes and method of preparing the same are disclosed herein. The disclosed herbo-mineral formulation includes herb and mineralelements which facilitate in treating Diabetes and Diabetes associated complications. Further the disclosed formulation has been observed to exhibit hypoglycemic, hypolipidemic, and pancreatic cell regenerative properties.

Description

[0001] Cross References to Related Applications [0002] This application is based on and derives benefit from Indian provisional application 201741006553 filed on 23 February 2017, the contents of which are incorporated herein by reference. technical field [0003] Embodiments disclosed in this specification relate to herbal-mineral formulations effective for the treatment, management and prevention of diabetes, especially diabetes and related complications. It also relates to methods of preparing such formulations. Background technique [0004] Diabetes is a disease associated with elevated blood sugar levels (hyperglycemia). The condition is the result of impaired glucose uptake by cells. Insulin promotes the uptake of glucose by cells from the bloodstream. Diabetes occurs when the pancreas does not produce enough insulin or the body is unable to use the insulin it produces. [0005] While family history is considered one of the risk factors for developing diabetes, ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/258A61K36/355A61K36/64A61K36/708A61K31/05A61K31/352
CPCA61K36/9066A61K36/27A61K36/328A61K36/37A61K36/47A61K36/59A61K36/61A61P3/10A61K36/00A61K35/02A61K35/10A61K2300/00A61K36/185A61K36/24
Inventor V·M·谢蒂
Owner MUNIYAL AYURVEDIC RES CENT
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