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Clinical application of Beffuxin gel as drug for repairing skin lesions with demodicidosis

A technology for demodicosis and demodex, which is applied in the field of clinical application of recombinant bovine basic fibroblast growth factor gel and medicine, to achieve high safety, skin lesions disappear, and definite clinical curative effect

Pending Publication Date: 2019-12-31
罗洋
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

At present, recombinant bovine basic fibroblast growth factor is mainly used in wound repair, such as burn wounds (including superficial II degree, deep II degree), chronic wound treatment (including surface chronic ulcers) and fresh wounds (including trauma, skin donor site Wounds, surgical injuries, etc.) and the treatment of corneal damage repair, but its application in the repair of demodicosis has not been reported

Method used

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  • Clinical application of Beffuxin gel as drug for repairing skin lesions with demodicidosis
  • Clinical application of Beffuxin gel as drug for repairing skin lesions with demodicidosis
  • Clinical application of Beffuxin gel as drug for repairing skin lesions with demodicidosis

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example 1

[0044] Typical case 1: Ma, male, 28 years old, suffered from "erythema, papules and nodules on the face, neck, chest and back for March" in November 2018 ( Figure 4a ) in the dermatology clinic of our hospital. The patient felt that the skin on the face, neck, chest and back was dry, accompanied by mild itching. The patient's skin lesions and hair follicle secretions were observed under a microscope for the presence of demodex mites, and the diagnosis was "demodicosis". The patient's skin lesions were scattered on the face, neck, chest and back, and manifested as erythematous papules with a diameter of about 0.3 to 2 cm. Festival. During treatment, clean the skin lesions with clean water at a moderate temperature, then apply recombinant bovine basic fibroblast growth factor gel at 300IU / cm 2 Apply directly to the patient's skin lesions, and instruct the patient to apply the medicine once in the morning and once in the evening. At the 4th week of repair, the color of the ery...

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Abstract

The invention relates to clinical application of a Beffuxin gel as a drug for repairing skin lesions with demodicidosis. Clinical cases prove that the recombinant bovine alkaline fibroblast growth factor gel can obviously repair skin inflammation symptoms, such as erythema and papules, caused by the demodicidosis, can obviously inhibit and cure nodules caused by inflammatory granuloma tissues in acorium layer with the demodicidosis, enables the skin lesions of the erythema and the papules of a patient with demodicidosis is cured and eliminated after the skin lesions are cured, and the nodulesformed by inflammatory granuloma are cured and turned for the better. Clinical tests verify that as a drug for repairing the demodicidosis, the recombinant bovine alkaline fibroblast growth factor gel is good in medication effect and high in safety, is easily accepted by the patient and is capable of relieving physical and psychological pains of the patient, so that a new therapeutic approach isopened up for the recombinant bovine alkaline fibroblast growth factor gel.

Description

technical field [0001] The invention belongs to the field of medicine, and relates to a new application of recombinant bovine basic fibroblast growth factor gel, specifically refers to the use of recombinant bovine basic fibroblast growth factor gel as a medicine for repairing demodicosis skin lesions. clinical application. Background technique [0002] Recombinant bovine basic fibroblast growth factor gel (recombinant bovine basic fibroblast growth factor, rbFGF), the trade name is Beifuxin (Zhuhai Yisheng Biopharmaceutical Co., Ltd.), which belongs to the class of fibroblast growth factor drugs (see figure 1 ). At present, recombinant bovine basic fibroblast growth factor is mainly used in wound repair, such as burn wounds (including superficial II degree, deep II degree), chronic wound treatment (including surface chronic ulcers) and fresh wounds (including trauma, skin donor site Wounds, surgical injuries, etc.) and corneal damage repair, but its application in the rep...

Claims

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Application Information

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IPC IPC(8): A61K38/18A61K9/06A61P33/14
CPCA61K38/1825A61K9/06A61K9/0014A61P33/14
Inventor 罗洋张剑虹吴岚曦周楠栾秀丽
Owner 罗洋
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