A Gel That Suppresses Acne
A technology for gel and acne, applied in acne skin care products and its preparation, in the field of sodium hyaluronate gel, which can solve problems such as the influence and instability of the gel's physical state, and achieve the promotion of wound healing, excellent lubricating effect, and increased The effect of dosage
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Embodiment 1
[0037] Example 1 Preparation of Sophora Sophora Extract and Forsythia Extract
[0038] The Sophora flavescens extract is prepared by the following method: take an appropriate amount of Sophora flavescens medicinal material, add 10 times the amount of water to soak for 30 minutes, boil on low heat, keep a slight boil for 30 minutes, filter, add 8 times the amount of water to decoct the filter residue for 30 minutes, keep Slightly boil, filter, combine the twice filtered decoction, concentrate the decoction under reduced pressure to a relative density of 1.15 (at room temperature), and spray dry to obtain Sophora flavescens extract;
[0039] The forsythia extract is prepared by the following method: take an appropriate amount of forsythia, crush it into a coarse powder, add 10 times the amount of water to decoct 3 times, each time for 1.5 hours, filter, combine the filtrate, and concentrate the filtrate under reduced pressure below 60°C To a clear paste with a relative density o...
Embodiment 2
[0040] Example 2 Preparation of Gel for Suppressing Acne
[0041] Weigh each raw material according to the ratio in the table below:
[0042]
[0043] Prepared as follows:
[0044] (1) Take Sophora flavescens extract, forsythia extract, ectoine, vitamin C or azelaic acid and add appropriate amount of purified water respectively, stir evenly to obtain solution A;
[0045] (2) Add sodium hyaluronate into solution A, stir evenly until the solution is clear and transparent, and obtain solution B;
[0046](3) Take glycerin, add ethylparaben to glycerin, stir evenly, and obtain solution C;
[0047] (4) Slowly add solution C to solution B, and stir while adding to make the mixture uniform, and the acne-suppressing gel is obtained.
[0048] Wherein, the pH value of sample 1 is 5.8, the pH value of sample 2 is 5.8, the pH value of sample 3 is 5.8, and the pH value of sample 4 is 5.0.
Embodiment 3
[0080] Embodiment 3 Physicochemical properties, antibacterial effect and therapeutic effect of different gel samples
[0081] 1. Gel properties of different samples
[0082] The sodium hyaluronate gel sample 1 that embodiment 2 makes and the carbomer gel sample 5 that comparative example 1 makes and the sodium carboxymethyl cellulose gel sample 6 that comparative example 2 makes carry out shear viscosity and shear frequency determination to compare the gel properties of the three:
[0083] Under the condition of 25±2°C, the rheometer was used at the shear rate from 0.001 s -1 -1000s -1 Peristaltic scanning was carried out under the following conditions, with the shear rate as the abscissa and the shear viscosity as the ordinate, the shear viscosity trend diagram of the test product was obtained. According to the trend diagram, select the appropriate shear rate in the first Newton zone, and measure the shear viscosity of the test product. The shear viscosity of sample 1 was...
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