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Application of macromolecular polysaccharide in removing inhalable particles in respiratory tracts

A technology of macromolecules and respiratory tract, which is applied in the field of environmental protection and can solve problems such as limited blocking rate

Inactive Publication Date: 2020-01-03
无锡锡喆生物医药有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] At present, more than 90% of PM in the total suspended dust emission 2.5 into the air, existing dust collection settings and personal protection against PM 2.5 The blocking rate is very limited

Method used

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  • Application of macromolecular polysaccharide in removing inhalable particles in respiratory tracts
  • Application of macromolecular polysaccharide in removing inhalable particles in respiratory tracts
  • Application of macromolecular polysaccharide in removing inhalable particles in respiratory tracts

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0040] An aerosol agent for removing inhalable particles in the respiratory tract, the raw materials of which include: 1 g of chitosan with a molecular weight of 500,000 and 100 g of water.

Embodiment 2

[0042] An aerosol agent for removing inhalable particles in the respiratory tract, the raw materials of which include: 40g of succinylated gelatin with a molecular weight of 1000 and 100g of water.

Embodiment 3

[0044] An aerosol agent for removing inhalable particles in the respiratory tract, the raw materials of which include: 10 g of hydroxyethyl starch with a molecular weight of 10,000 and 100 g of water.

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PUM

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Abstract

The invention discloses an application of macromolecular polysaccharide in removing inhalable particles in respiratory tracts. The invention further discloses an atomizing agent for removing the inhalable particles in the respiratory tracts. The atomizing agent comprises the following raw materials: macromolecular polysaccharide and water. The macromolecular polysaccharide is at least one of dextran, hydroxyethyl starch, cellulose, starch, glycogen, hemicellulose, alginic acid, glucosaminoglycan, heparan sulfate, succinylated gelatin, polygeline, chondroitin sulfate and hyaluronic acid. Respiratory tract spray of a macromolecular polysaccharide solution can increase respiratory tract wetness. Meanwhile, the macromolecular polysaccharide can effectively adsorb and wrap inhaled fine particulate matter (PM2.5). Finally, the macromolecular polysaccharide-fine particulate matter adsorption wrappage is pushed to the upper respiratory tract through ciliary movement of bronchial epithelium, and the macromolecular polysaccharide-fine particulate matter adsorption wrappage is discharged out of the body through cough.

Description

technical field [0001] The invention relates to the technical field of environmental protection, in particular to the application of a macromolecular polysaccharide in removing inhalable particles in the respiratory tract. Background technique [0002] Dust suspended in the atmosphere is regarded as a kind of particulate matter, and its particle size is usually 0-100 µm. The most harmful to human body is inhalable particulate matter (PM 10 , 0~10µm), fine particulate matter (PM 2.5 , 0~2.5µm) and ultrafine particulate matter (PM 0.1 , 0~0.1µm). Inhalable particles, fine particles and ultrafine particles are characterized by small particle size, not easy to decompose, and slow sedimentation rate, so they can stay in the air for a long time and have a large diffusion range. [0003] The entire respiratory tract of the human body has three protective barriers: 1. Nose hair prevents bacteria, viruses and dust from entering the respiratory tract; 2. Mucus secreted by tracheal...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/72A61K9/12A61K47/36A61K31/4425A61P11/00A61P31/02
CPCA61K9/0078A61K31/4425A61K47/36A61P11/00A61P31/02
Inventor 于东防方超江根生
Owner 无锡锡喆生物医药有限公司
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