57 results about "SIDS - Sudden infant death syndrome" patented technology

Compositions including a non-pathogenic lactic acid-producing bacteria, such as a Bacillus species, spores or an extracellular product of B. coagulans, formulated for oral administration to the intestinal tract for inhibiting bacterial gastrointestinal infections are described. Methods and systems using the compositions for treating gastrointestinal infections, particularly sudden infant death syndrome (SIDS) are also disclosed.

The invention relates to a method of treating diverse human disorders that may arise, in part, out of sleep hypoxia and oxygen deprivation occurring in the context of sleep apnea/hypopnea disturbances. The disorders that may be treated by the invention comprise gastroesophageal reflux disease (GERD), asthma-associated gastroesophageal reflux (GER), GER-associated asthma, asthma, cardiomyopathy, cardioarrhythmia, congestive heart failure, sudden infant death syndrome, and diverse neurologic conditions. The mode of treatment uses somatostatin receptor ligands (SstRLs), particularly somatostatin-receptor agonists. The invention concerns the method of treatment utilizing, and compositions comprising SstRLs and somatostatin receptor agonists, including agonists of the somatostatin receptor types 2 and 5, particularly, the type 2A receptor (SsR-2A), including octreotide and lanreotide.

A portable monitoring device for monitoring of the short term, mid term and long term risks of Sudden Infant Death Syndrome (SIDS) and to estimate the risk of onset of positional plagiocephaly. The monitoring device acquires one or more signals associated to the typical breath and positioning patterns of an infant through a tri-axial accelerometer, and registers the data in electronic format, where statistical analysis of the signal and pattern recognition are performed in real time by a processing unit. The device monitors the breath activity of an infant in various conditions, alerting a caregiver when a potentially dangerous situation is detected. The monitoring is attached to the clothes of the infant. Statistical analysis of the registered data is performed for quantifying the long term SIDS risk, the risk of plagiocephaly and for optimizing the functional parameters of the monitoring device.

Methods and apparatuses for monitoring breathing pattern by monitoring and analyzing data that are the results of pressure changes in an air bed due to amount of air inhaled and exhaled and the chest expansion and contraction of an infant. The changes in pressure over time can be recorder, modeled and sent to be analyzed for fault detection in breathing pattern. As a result the abnormalities in the breathing pattern can be detected and parents and pediatrics can be warned in case of an Apparent Life-Threatening Event (ALTE) to prevent Sudden Infant Death Syndrome (SIDS).

A ventilation system that includes a fan for providing fresh air within an infant's sleeping area. The fan may be mounted to the infant's sleeping device and may include fan guards surrounding the fan for increased safety. The ventilation system may include a sensing device for monitoring the conditions within the infant's sleeping area. The sensing device may monitor the oxygen level, the carbon dioxide level, and the presence of smoke. The sensing device may monitor for additional toxic gasses or hazardous conditions within the infant's sleeping area. The ventilation system may further include a remote receiver that receives signals from the sensing device if a hazardous condition exists within the infant's sleeping area. The ventilation system may further include local and remote alarms configured to provide notification of a hazardous condition within the infant's sleeping area.

A spacer fabric in combination with an infant mattress pad is provided. The spacer fabric has three parts or components knitted together to form a fabric with two breathable outer fabric layers and a breathable cushioned middle defined by yarns interconnecting the two layers. The spacer fabric is incorporated into an infant mattress pad in order to create an infant safety and comfort system designed to help reduce the risk of sudden infant death syndrome (SIDS) and also to provide infants with enhanced comfort.

The present invention provides novel compounds of Formula I

and salts, hydrates, solvates, complexes, and prodrugs thereof. The present invention further provides methods for synthesizing compounds of Formula I. The invention additionally provides pharmaceutical compositions comprising the compounds of Formula I and methods of using the pharmaceutical compositions of Formula I to treat and prevent disorders and diseases associated with the RyR receptors that regulate calcium channel functioning in cells. Such disorders and diseases include, by way of example only, cardiac disorders and diseases, skeletal muscular disorders and diseases, cognitive disorders and diseases, malignant hyperthermia, diabetes, and sudden infant death syndrome. Cardiac disorder and diseases include, but are not limited to, irregular heartbeat disorders and diseases; exercise-induced irregular heartbeat disorders and diseases; sudden cardiac death; exercise-induced sudden cardiac death; congestive heart failure; chronic obstructive pulmonary disease; and high blood pressure. Irregular heartbeat disorders and diseases include and exercise-induced irregular heartbeat disorders and diseases include, but are not limited to, atrial and ventricular arrhythmia; atrial and ventricular fibrillation; atrial and ventricular tachyarrhythmia; atrial and ventricular tachycardia; catecholaminergic polymorphic ventricular tachycardia (CPVT); and exercise-induced variants thereof. Skeletal muscular disorder and diseases include, but are not limited to, skeletal muscle fatigue, exercise-induced skeletal muscle fatigue, muscular dystrophy, bladder disorders, and incontinence. Cognitive disorders and diseases include, but are not limited to, Alzheimer's Disease, forms of memory loss, and age-dependent memory loss.

The present invention relates to compositions and methods of alleviating a symptom of sleep apnea, snoring associated with and independent of sleep apnea, and/or sudden infant death syndrome by administering oxytocin. Specifically, the invention includes a method of administering oxytocin or a salt thereof to an animal in order to treat obstructive sleep apnea, snoring associated with and independent of sleep apnea, and sudden infant death syndrome.

A device (1)(2) and method to monitor, in real time, one or more variables by an at least 2500 hour water proof sensor/transmitter, not requiring recharge, placed at the source where data are automatically collected and transmitted by wire or wireless means (2A)(2B) to a battery-free computer-powered (2C) receiver connected to a computer, where software continuously analyzes and charts the data. The software auto and cross correlates the variables, continuously updates and displays the data on simple aggregate charts (4A) or decomposes the data and displays them on newly created common cause charts (4B)(4C) of internal systematically related effects and newly created special cause charts (4D)(4E) of external random unrelated effects, including summary data, and creates graduated progressive sound, color, print and world wide, fax, email and telephone alarm signals when the chart values exceed user specified limits, either in terms of actual units (4B)(4D) or standard deviations (4C)(4E), or when any particular pattern occurs. The device helps determine ahead of time, when the source of the monitored variables is functioning abnormally. Advance warning thus obtained, is used to initiate corrective action (3A)(3B)(3C)(3D) so as to prevent failure at the source that is generating the variables. Examples of failure that it helps prevent include but are not limited to, sudden infant death due to sudden infant death syndrome in human babies, heart or respiratory failure in any human being who is either at rest or moving around within a specified area, failure in industrial machines or measuring equipment, manufacturing defects and financial irregularities.

The present invention provides compositions useful for treating and preventing ryanodine receptor associated disorders comprising a PDE-associated agent and a pharmaceutically acceptable carrier. The present invention also provides methods for treating or preventing ryanodine receptor associated disorders including cardiac disorders and diseases, skeletal muscular disorders and diseases, cognitive disorders and diseases malignant hyperthermia, diabetes and sudden infant death syndrome. The present invention further provides methods for regulating PKA phosphorylation of a ryanodine receptor as well as methods for regulating Ca+2 release and reuptake in cells. Also provided are kits for use in delivering a PDE-associated agent to cardiac cells in a subject, comprising the composition of the present invention and a catheter.

The present invention provides a method and apparatus for monitoring infant respiration during sleep. More specifically, the present invention alerts the caregiver when an infant has ceased to breathe during sleep. The usefulness of such device applies to Sudden Infant Death Syndrome (SIDS) and prolonged apnea leading to a life threatening event. One embodiment of a method according to the present invention comprises monitoring the relative level of humidity from an infant respiration and comparing it to the room ambient relative humidity. A determination is made when an infant has stopped breathing once the level of the humidity from the infant breaths approaches the room humidity level. At such time, the present invention provides an alert to the caregiver to allow appropriate actions to be taken in reviving or waking the infant as applicable.

Systems and methods for detecting, monitoring and profiling/correlating a subject's motions, such as rollovers, falls, shaking and tremors are disclosed. In particular, an infant's mobility event may cause critical event processing indicating that an infant has rolled over and may be suffocating. Such an event is classified as a Sudden Infant Death Syndrome (SIDS)-like event. The system may include a wireless pendant device and a wireless monitor server. The wireless pendant device is configured to measure acceleration motion of a subject, to generate acceleration data from the acceleration motion and to communicate the acceleration data with the wireless monitor server. The wireless monitor server is configured to analyze the acceleration data communicated by the wireless pendant device and to provide an output related to the analysis.

A monitoring system for sudden infant death syndrome alerts parents, including parents who are blind and deaf, of changes in their infant's health condition. The system comprises three parts: a portable monitoring and warning control unit, a sensor bracelet that would be placed around the infant's wrist and an alarm bracelet for blind and deaf parents. The infant sensor bracelet comprises multiple sensors and a microphone and transceiver to receive and transmit data to a portable control monitoring unit. A similar system is provided for blind and deaf parents. The vibration alarm units each have Braille characters printed in the top to enable a blind person to identify the vibration alarm. A portable monitoring and warning control unit comprises at least a transceiver to communicate with the bracelets and a processing control unit to collect data and compare it with thresholds/acceptable ranges.

Systems relating to a safe and easily removable and reusable waterproof pad with accompanying bottom layer that attaches to a crib mattress. The detachable waterproof pad of the present invention seeks to reduce the risk of sudden infant death syndrome (SIDS) by providing a tightly fitted pad to comply with current SIDS recommendations. The pad can be changed, cleaned, and replaced frequently.

An infant remote monitoring system utilizes a heat detector to monitor the baby temperature from breath to prevent from the Sudden Infant Death Syndrome (SIDS).