Application of blue copper peptide in preparing medicines for leucoderma and medicines for treating leucoderma

Abstract

The present invention relates to an application of blue copper peptide in preparing medicines for treating leucoderma. The blue copper peptide is a glycine-histidine-lysine-copper compound, copper ions in the blue copper peptide enter human body melanocytes under action of the blue copper peptide, the copper ion is combined with a copper A site on tyrosinase in the melanocytes under action of histidine, combination of the copper ion and the copper A site promotes combination of the copper ion and a copper B site, an endogenous bridge group connects the two copper ions together to form an active center of oxidation reaction, so that activity of the tyrosinase is improved, tyrosine is promoted to generate dopa, the dopa generates dopaquinone under the action of the tyrosinase, the dopaquinone further reacts to generate melanin, and thus the blue copper peptide promotes generation of the melanin, improves states of skin pigment reduction or loss and achieves a purpose of treating the leucoderma.

Description

technical field [0001] The invention belongs to the field of medicine, and in particular relates to the application of blue copper peptide in the preparation of medicine for treating vitiligo and the medicine for treating vitiligo containing the same. Background technique [0002] Vitiligo is a common acquired localized or generalized skin depigmentation disease caused by the loss of the function of melanocytes in the skin to produce melanin. In recent years, the incidence of vitiligo has a tendency to increase significantly, but its etiology and pathogenesis are still unclear. Statistics show that vitiligo is characterized by the loss of melanin production by melanocytes on the skin surface, mucous membranes and other functions, and usually occurs in young people. And children, the incidence rate gradually decreases with age. For the inducement of vitiligo, scientists have tried for long-term research from genetics, lack of trace elements, especially low copper ion content...

AI Technical Summary

Problems solved by technology

The causes of vitiligo are complex, and there are many theories coexisting at present, but it is an indisputable fact that the loss of melanocyte function causes vitiligo

In the prior art, there are many medicines for the treatment of vitiligo, and the mechanism of the treatment basis is different, but the effects are not very satisfactory.

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