Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Molecular genetic marker related to rate of teratosperm of pigs and application

A technology of molecular genetic markers and sperm deformity, applied in the field of molecular genetic biology, can solve the problems of overestimation of marker effects, high calculation intensity, unreasonable setting of significance threshold, etc., and achieve the goal of reducing the rate of sperm deformity and improving utilization efficiency Effect

Pending Publication Date: 2020-01-21
FOSHAN UNIVERSITY
View PDF5 Cites 1 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Such methods often face problems such as high computational intensity, overestimation of marker effects, and unreasonable setting of significance thresholds.

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Molecular genetic marker related to rate of teratosperm of pigs and application
  • Molecular genetic marker related to rate of teratosperm of pigs and application
  • Molecular genetic marker related to rate of teratosperm of pigs and application

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0045] A method for screening molecular genetic markers related to porcine sperm deformity rate, the specific steps are:

[0046] 1. Collect pig phenotype-pedigree data

[0047] The pedigree of the breeding pigs is sorted out, mainly including boar individual number, father, mother and date of birth, etc. The basic research population of this disclosure is Duroc boars, all of which come from the boar station of Guangxi Xiubo Co., Ltd. The complete pedigree contains 12 generations of 5284 breeding pigs, among which the phenotype data of sperm deformity rate traits of 2693 boars were recorded from 2015 to 2018. The UltiMateTM CASA (Hamilton Thorne Inc., Beverly, MA, USA) system was used to test Perform analysis to obtain the phenotypic data of sperm deformity rate traits, and obtain 143,114 observations of semen traits (53 data per boar on average), which are used for phenotype-genotype correlation analysis;

[0048] 2. Carry out pig genotyping and quality control, and obtain g...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention provides a molecular genetic marker related to the rate of teratosperm of pigs. A molecular genetic marker site is ALGA0108896, the marker site of ALGA0108896 is located at the 24920078bp G>T mutation site in the pig NO.3 chromosome, and a pig reference genome is Sscrofa11.1. According to the molecular genetic marker related to the rate of teratosperm of the pigs, the rates of teratosperm of boars of different genotypes have significant differences, the T allele significantly reduces the rate of teratosperm, the genotype of the ALGA0108896 molecular genetic marker site can be detected to assist the breeding of the boars, homozygous boars with a low rate of teratosperm are selected and reserved, the rate of teratosperm is reduced, and the boar utilization efficiency is effectively improved.

Description

technical field [0001] The disclosure belongs to the field of molecular genetic biotechnology, and in particular relates to a molecular genetic marker related to the malformation rate of pig sperm and its application. Background technique [0002] Artificial insemination (AI) has been applied in my country since 1954. After decades of technical improvement and integration and national support, artificial insemination technology is becoming more and more mature in my country, and its application in large and medium-sized farms is also basically popular. The advantage of artificial insemination is that it not only improves the utilization rate of good boars, but also timely detects and records the quality of boar semen. At the same time, the health status and reproductive potential of boars can be monitored through the evaluation of semen quality, so as to optimize the individual genetic potential and maximize the reproductive capacity. [0003] In the process of artificial i...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): C12Q1/6888C12N15/11G16B20/20G16B20/40G16B20/50G16B40/00
CPCC12Q1/6888G16B20/40G16B20/20G16B20/50G16B40/00C12Q2600/156C12Q2600/124
Inventor 李智丽袁生张楠池仕红喻维维邝伟健王美红
Owner FOSHAN UNIVERSITY
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com