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Chinese wampee leaf extract drop pill and preparation method thereof

A technology of extract and yellow skin leaf, applied in the field of yellow skin leaf extract drop pills and its preparation, achieves the effect of simple preparation method, high content of quercetin, and good repeatability

Inactive Publication Date: 2020-02-07
高州市大田顶农业发展有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

According to the literature search, there are few relevant researches on the dosage form of wampum leaf extract

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0021] A kind of wampum leaf extract dripping pill, the parts by weight of each component are:

[0022] 90 parts of wampum leaf extract, 80 parts of PEG4000, 50 parts of PEG6000, 60 parts of F68.

[0023] A kind of preparation method of yellow bark leaf extract dripping pill, comprises the following steps:

[0024] (1) Raw material pretreatment: pass the extract of wampum bark leaves through a 100-mesh sieve, and grind and crush the substrates PEG4000, PEG6000 and F68, and pass through a 100-mesh sieve;

[0025] (2) Ingredients: Accurately weigh the wampum leaf extract and the matrix according to the weight of each component and mix them evenly;

[0026] (3) Melting: heat the mixed components at 95°C to melt;

[0027] (4) Granulation: Add the liquid medicine to the feed liquid tank of the dropping pill machine, control the temperature of the feed liquid to 70°C, and the temperature of the condensate to 15°C, use dimethyl silicone oil as the condensate, and prepare drop pills...

Embodiment 2

[0030] A kind of wampum leaf extract dripping pill, the parts by weight of each component are:

[0031] 60 parts of wampum leaf extract, 50 parts of PEG4000, 60 parts of PEG6000, 70 parts of F68.

[0032] A kind of preparation method of yellow bark leaf extract dripping pill, comprises the following steps:

[0033] (1) Raw material pretreatment: pass the extract of wampum bark leaves through a 100-mesh sieve, and grind and crush the substrates PEG4000, PEG6000 and F68, and pass through a 100-mesh sieve;

[0034] (2) Ingredients: Accurately weigh the wampum leaf extract and the matrix according to the weight of each component and mix them evenly;

[0035] (3) Melting: heat the mixed components at 95°C to melt;

[0036] (4) Granulation: Add the liquid medicine to the feed liquid tank of the dropping pill machine, control the temperature of the feed liquid to 80°C, and the temperature of the condensate to 15°C, use dimethyl silicone oil as the condensate, and prepare drop pills...

Embodiment 3

[0039] A kind of wampum leaf extract dripping pill, the parts by weight of each component are:

[0040] 70 parts of wampum leaf extract, 60 parts of PEG4000, 80 parts of PEG600000, 80 parts of F68.

[0041] A kind of preparation method of yellow bark leaf extract dripping pill, comprises the following steps:

[0042] (1) Raw material pretreatment: pass the extract of wampum bark leaves through a 100-mesh sieve, and grind and crush the substrates PEG4000, PEG6000 and F68, and pass through a 100-mesh sieve;

[0043] (2) Ingredients: Accurately weigh the wampum leaf extract and the matrix according to the weight of each component and mix them evenly;

[0044] (3) Melting: heat the mixed components at 95°C to melt;

[0045] (4) Granulation: Add the liquid medicine to the feed liquid tank of the dropping pill machine, control the temperature of the feed liquid to 80°C, and the temperature of the condensate to 15°C, use dimethyl silicone oil as the condensate, and prepare drop pil...

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Abstract

The invention relates to a Chinese wampee leaf extract drop pill and a preparation method thereof, and belongs to the technical field of medical processing. Specifically, Chinese wampee leaf extract is used as a raw material, PEG4000, PEG6000 and F68 are used as substrates, the temperature of a material liquid is controlled to 70-80 DEG C, the temperature of condensate is 10-15 DEG C, the drop pill is prepared by using a dropping method, and the obtained Chinese wampee leaf extract drop pill is dried by hot air at 35 DEG C. The preparation method of the Chinese wampee leaf extract drop pill issimple and good in repeatability, the roundness, the pill weight difference and the time limit of dissolution of the prepared drop pill all meet the requirements under the drop pill item of the general items of the IV part of the Chinese Pharmacopoeia 2015 version, the quercetin content is high, and the stability test suggests that the Chinese wampee leaf extract drop pill need to be kept in lowtemperature, dry and away from light

Description

technical field [0001] The invention relates to a yellow bark leaf extract dripping pill and a preparation method thereof, belonging to the field of pharmaceutical processing. Background technique [0002] Rutaceae plant wampum is produced in Fujian, Guangdong, Taiwan, Guangxi, Yunnan and other places in southern my country. Its leaves have the effect of dispelling wind and relieving the exterior, eliminating phlegm and promoting qi, and can treat febrile diseases, body heat, cough and asthma, flatulence, abdominal pain, yellow swelling , malaria, dysuria, heat poisonous scabies and other diseases. Folks use its leaves to boil water and bathe to treat scabies, wind and swelling. In recent years, it has been reported that xanthamide in xanthophyll leaves has biological activities such as protecting the liver and promoting intelligence. In addition, Li Weixun and others used the water extract of Huangpi leaves to have certain curative effect in the treatment of acute jaundice...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/75A61K9/20A61K47/10A61P1/16A61P39/02A61P39/06A61P3/06A61P31/04A61P35/00A61P31/12A61P3/10A61P9/12A61P9/00A61P37/02A61P25/00A61P17/00A61K127/00
CPCA61K9/2031A61K36/75A61P1/16A61P3/06A61P3/10A61P9/00A61P9/12A61P31/04A61P31/12A61P35/00A61P37/02A61P39/02A61P39/06
Inventor 赖梓洋
Owner 高州市大田顶农业发展有限公司
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