A kind of preparation method of 2-acrylamido-2-methylpropanesulfonic acid
A technology of methylpropanesulfonic acid and acrylamide, which is applied in the field of preparation of 2-acrylamido-2-methylpropanesulfonic acid, which can solve the problems of large refining and purification losses, multiple by-product impurities, and poor product quality. , to achieve the effect of less solvent residue, high dissolution clarity and low product loss
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Embodiment 1
[0031] Preparation of crude 2-acrylamido-2-methylpropanesulfonic acid:
[0032] The raw material acrylonitrile and nicotinic acid are mixed at low temperature, and then isobutylene is introduced to obtain a slurry, which is filtered and dried to obtain a crude 2-acrylamido-2-methylpropanesulfonic acid with a liquid phase purity of 97.1%.
[0033] (1) Add 200g of crude 2-acrylamido-2-methylpropanesulfonic acid and 0.0152g of p-hydroxyanisole to a mixed solution of 128g of purified water and 32g of ethanol at room temperature, and stir to dissolve;
[0034] (2) Add 3.6g of activated carbon. After stirring for 30 min, it was filtered.
[0035] (3) Control the temperature to 15°C, the stirring speed is 200 rpm, and add acetone dropwise to the filtrate. After a period of time, the solution becomes turbid, and the speed is adjusted to 180 rpm;
[0036] Continue to drip at a slow and uniform speed for 2h, and add 1800g of acetone dropwise;
[0037] After 1 h, the temperature was l...
Embodiment 2
[0039] Preparation of crude 2-acrylamido-2-methylpropanesulfonic acid:
[0040] The raw material acrylonitrile and nicotinic acid are mixed at low temperature, and then isobutylene is introduced to obtain a slurry, which is filtered and dried to obtain a crude 2-acrylamido-2-methylpropanesulfonic acid with a liquid phase purity of 97.1%.
[0041] (1) At room temperature, add 200g of crude 2-acrylamido-2-methylpropanesulfonic acid and 0.02g of p-hydroxyanisole to a mixed solution of 140g of purified water and 60g of ethanol, and stir to dissolve;
[0042] (2) Add 5g of activated carbon. After stirring for 30 min, it was filtered.
[0043] (3) Control the temperature to 18°C, the stirring speed is 200 rpm, and add acetone dropwise to the filtrate. After a period of time, the solution appears turbid, and the speed is adjusted to 180 rpm;
[0044] Continue to drip at a slow and uniform speed for 2.5h, and add 2000g of acetone dropwise;
[0045] After 1 h, the temperature was lo...
Embodiment 3
[0047] Preparation of crude 2-acrylamido-2-methylpropanesulfonic acid:
[0048] The raw material acrylonitrile and nicotinic acid are mixed at low temperature, and then isobutylene is introduced to obtain a slurry, which is filtered and dried to obtain a crude 2-acrylamido-2-methylpropanesulfonic acid with a liquid phase purity of 97.1%.
[0049] (1) At room temperature, add 200g of crude 2-acrylamido-2-methylpropanesulfonic acid and 0.012g of p-hydroxyanisole to a mixed solution of 135g of purified water and 45g of ethanol, and stir to dissolve;
[0050] (2) Add 4g of activated carbon. After stirring for 30 min, it was filtered.
[0051] (3) Control the temperature to 13°C, the stirring speed is 200 rpm, and add acetone dropwise to the filtrate. After a period of time, the solution becomes turbid, and the speed is adjusted to 180 rpm;
[0052] Continue to drip at a slow and uniform speed for 2.5h, and add 2280g of acetone dropwise;
[0053] After 1 h, the temperature was l...
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