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A Portable Programmable Parallel Fluid Control Flat Squeeze Microvalve Device

A control board, portable technology, applied in the direction of valve device, valve operation/release device, sliding valve, etc., can solve the problems of miniaturization and portability of the lab-on-a-chip, reducing the reliability of micro-valve control, and the complex structure of the micro-valve system and other problems, to achieve the effect of easy parallel expansion, reliable performance, and cost reduction

Active Publication Date: 2021-06-25
DALIAN MARITIME UNIVERSITY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The current active microvalve requires more mechanical and electronic structures or external equipment such as air pressure and vacuum in multi-channel parallel control, resulting in a complex structure of the microvalve system, difficult design and processing, and high cost, which is not conducive to the chip laboratory. Miniaturization and portability, and more mechanical structures also reduce the reliability of microvalve control

Method used

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  • A Portable Programmable Parallel Fluid Control Flat Squeeze Microvalve Device
  • A Portable Programmable Parallel Fluid Control Flat Squeeze Microvalve Device
  • A Portable Programmable Parallel Fluid Control Flat Squeeze Microvalve Device

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0022] figure 1 It is a schematic diagram of a single valve structure of a portable programmable parallel fluid control flat extrusion microvalve device, by figure 1 As shown, the present invention includes a control board 1, and a microvalve support 3 is provided with a semi-wrap around the control board 1, and a control board track 31 is arranged in the microvalve support 3, the control board 1 is connected with the control board driving motor 2, and the control board driving motor 2 The control board 1 can be driven to slide on the control board track 31, and the microfluidic chip 5 is arranged parallel to the control board 1. 11 is an arc-shaped groove. The microfluidic chip 5 is provided with a fluid microchannel 51. The fluid microchannel 51 is provided with a valve stem 4 on the side close to the control board 1. The two ends of the valve stem 4 are smooth, and one end is connected to the fluid microchannel. 51 is in contact with the microfluidic chip 5 on the side clo...

Embodiment 2

[0025] The portable programmable parallel fluid control plate extrusion microvalve device of the present invention is composed of a control board 1 , a control board driving motor 2 , a microvalve bracket 3 , a valve stem 4 and a microfluidic chip 5 . The control board 1 is connected to the control board driving motor 2, and the lower surface of the control board 1 is processed with grooves with specific radians and depths according to the control process of multiple parallel valve stems, as the valve stem slideway 11, the valve stem slideway The trend of 11 is consistent with the trend of the control board 1; the control board 1 is arranged in the microvalve bracket 3, and the microvalve bracket 3 includes a control board track 31 for fixing the control board 1 and a valve stem for fixing the valve stem 4 Through hole 32 . The structure of the control board track 31 of the control board 1 is effectively matched, so that the control board 1 can slide in the predetermined direc...

Embodiment 3

[0029] Figure 4 It is a structural schematic diagram of the control board integrated with the operating program of the three-way microvalve, which includes three valve stem slideways.

[0030] In this embodiment, the depth of the valve stem slideway 11 is 2 mm, and the length is 8 mm. The side profile of the arc slope on both sides is a quarter of an ellipse with a major axis of 6 mm and a minor axis of 4 mm, and the rounded corners are processed by a grinder.

[0031]In actual use, the control board is in contact with the valve stem 4 at side A in the initial state, and all three channels are in a closed state at this time. After the experiment process starts, the motor drives the control board 2 to slowly move from side A to side B, and the three valve stems 4 move up and down according to the structure of their respective slideways, and the corresponding microfluidic channels are controlled to open and close according to the pre-programmed program . Specifically, in the ...

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Abstract

The invention discloses a portable programmable parallel fluid control plate extrusion microvalve device, which belongs to the field of microfluidic chips. The present invention includes a control board integrating the operating program of multiple parallel microvalves and a plurality of valve stems with specific radians and rounded corners at both ends; a plurality of parallel grooves with specific radians and depths are processed on the surface of the control board as The valve stem slideway, the structure of the valve stem slideway is designed according to the control flow of the corresponding valve stem, and the operating state of the corresponding valve stem is controlled. The valve stem moves up and down with the movement of the control plate in the slideway and squeezes the elastic microchannel, thereby changing the opening and closing state of the channel and realizing programmable parallel fluid control. The microvalve device of the present invention can automatically complete the entire microfluidic control process in a programmable, high-synchronization, and multi-parallel state, and has reliable performance, easy function expansion and integration, and the device has good portability, low cost, and strong practicability, which is beneficial to Further construction of a real-time on-site microfluidic control system has broad application prospects.

Description

technical field [0001] The invention belongs to the field of microfluidic chips, in particular to a portable programmable parallel fluid control plate extrusion microvalve device. Background technique [0002] Microfluidics refers to the science and technology involved in systems that use micropipes (tens to hundreds of microns in size) to process or manipulate tiny fluids (nanoliters to picoliters in volume). , fluid physics, microelectronics, new materials, emerging interdisciplinary disciplines of biology and biomedical engineering. Because of the characteristics of miniaturization and integration, microfluidic systems are often called microfluidic chips, also known as Lab on a Chip. One of the important characteristics of microfluidics is that fluids have unique properties in micro-scale environments, such as laminar flow and droplets. With the help of these unique fluid phenomena, microfluidics can realize a series of fluid manipulation and control that are difficult ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): F16K3/02F16K31/04
CPCF16K99/0011F16K99/0042F16K2099/0084
Inventor 钟润涛王少华王梦雨孙野青
Owner DALIAN MARITIME UNIVERSITY
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