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A kind of nmn+glp compound nutritional supplement and its preparation method and application

A nutritional supplement, Ganoderma lucidum technology, applied in the field of biomedicine, can solve the problems of inability to meet consumers' requirements for anti-aging, health care, lack of targeting effect, unclear side effects, etc., to increase the proliferation of Ganoderma lucidum polysaccharide cells and avoid side effects. , to avoid the effect of reducing the efficacy of the drug

Active Publication Date: 2021-03-19
分子态(珠海横琴)中医药健康产业发展有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] Although the application of NMN is constantly expanding in the current situation, in order to ensure a certain drug effect, most NMN-related products are recommended to be taken in larger doses every day, and their main function is cell repair, but they lack targeting. It cannot meet the requirements of consumers for anti-aging and health care, and any possible side effects of large doses of NMN on the human body are not clear
[0005] In view of the above problems, it is necessary to provide a compound preparation, which can not only ensure the good drug effect of NMN, but also have the effect of cell repair and multi-target cell proliferation, and can reduce the daily intake and avoid long-term massive Decreased drug efficacy or possible side effects after taking

Method used

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  • A kind of nmn+glp compound nutritional supplement and its preparation method and application
  • A kind of nmn+glp compound nutritional supplement and its preparation method and application
  • A kind of nmn+glp compound nutritional supplement and its preparation method and application

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0038] A NMN+GLP compound nutritional supplement, its formula is: NMN monomer 150mg, red Ganoderma lucidum and purple Ganoderma lucidum extract equal mixture (namely Ganoderma heteropolysaccharide) 450mg, made into capsule preparation, each capsule 600mg.

[0039] A kind of NMN+GLP compound nutritional supplement, its formula is: NMN monomer 150mg, the extracts of Versicolor versicolor, Ganoderma lucidum, Boca lucidum, Ganoderma flat cover, Phellinus, Inonotus obliquus and Phylonotus rubrum in equal amounts Mixture (namely ganoderma heteropolysaccharide) 450mg.

[0040] The above-mentioned extract of Ganoderma lucidum is extracted according to the provisions in Part One of Pharmacopoeia.

Embodiment 2

[0042]Through group comparative investigation, research the effect of the product of the present invention on four aspects such as improving sleep, enhancing energy, improving complexion and effect feeling.

[0043] The components of the NMN+GLP compound nutritional supplement prepared in this example: 150 mg of NMN monomer, 450 mg of mixed extracts of red Ganoderma lucidum and purple Ganoderma lucidum (ie heteropolysaccharides of Ganoderma lucidum), made into capsule preparations, 600 mg per capsule.

[0044] The basis for the dosage of ganoderma heteropolysaccharides is: According to the Chinese Pharmacopoeia, the usage and dosage of ganoderma lucidum decoction pieces are: 6-12g, decocted in water. Based on the extraction rate of 5%, it is equivalent to 300-600mg of Ganoderma lucidum extract.

[0045] In this program, 200 people were randomly invited to participate in the experiment, divided into 4 groups, 50 people in each group. Each person in the first group provided 28 ...

Embodiment 3

[0058] Through group comparative investigation, research the best composite ratio of the product of the present invention in four aspects such as improving sleep, improving energy, improving complexion and effect feeling.

[0059] Based on the recommended dosage of NMN is 300mg to 1000mg per day; the dosage of Ganoderma lucidum extract is recommended to be 300-600mg per day; according to the maximum dosage of Ganoderma lucidum, the product specification is designed as the following experimental plan with a total content of 600mg:

[0060] In this program, 300 people were randomly invited to participate in the experiment, divided into 6 groups, 50 people in each group. Each person in the first group provided 28 capsules filled with NMN accounting for 10% and Ganoderma lucidum extract accounting for 90%; the second group provided each person filling NMN accounting for 20% and Ganoderma lucidum extract accounting for 80% % of 28 capsules; each person in the third group provided 2...

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Abstract

The invention discloses an NMN + GLP compound nutritional supplement as well as a preparation method and application thereof. The NMN + GLP compound nutritional supplement is prepared from the following components in percentage by weight: 20-50% of beta-nicotinamide mononucleotide and 50-75% of ganoderma lucidum heteropolysaccharide. The effects of NMN in resisting aging, improving the sleep quality of the middle-aged and elderly people, and the effects of ganoderma lucidum heteropolysaccharide GLP in tonifying qi and calming the nerves are not just simply combined, but mutual synergist of NMNand GLP is achieved; because of the compounding effect of ganoderma lucidum heteropolysaccharide GLP active carrier, NMN drug effect is ensured, the daily using amount is reduced, on one hand, the cost is reduced, and on the other hand, the medicine effect reduction or possible side effects caused by long-term large-scale taking are also avoided; meanwhile, NMN also can improve the proliferationfunction of ganoderma lucidum polysaccharide cells, and the effect of the compound nutritional supplement is improved. Besides, the stability of the compound nutritional supplement is improved, the compound nutritional supplement can be prepared into various common dosage forms, the compound nutritional supplement is convenient to take and carry, and the compliance of users is improved.

Description

technical field [0001] The present invention relates to the technical field of biomedicine, and more specifically, relates to an NMN+GLP compound nutritional supplement and its preparation method and application. Background technique [0002] β-nicotinamide mononucleotide, English name: BETA-NICOTINAMIDEMONONUCLEOTIDE; Abbreviation: NMN; Molecular formula: C 11 h 15 N 2 o 8 P; molecular weight: 334.22. NMN is an inherent substance in the human body and has important physiological functions for human cells. It can be synthesized naturally in cells and can also be derived from a variety of foods, including broccoli, cabbage, cucumber, edamame, avocado, etc. NMN is a synthetic NAD in the human body + The precursor of NAD, its physiological function is mainly through increasing NAD + level to reflect. NAD + Also called coenzyme Ⅰ, the full name is nicotinamide adenine dinucleotide. NAD + In cells, it not only serves as a coenzyme, but also serves as a substrate for var...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K31/715A61K31/706A61P3/02A61P3/04A61P3/06A61P3/10A61P9/12A61P9/00A61P35/00A61P37/04A23L33/10A23L33/125
CPCA23V2002/00A61K31/706A61K31/715A23L33/10A23L33/125A61P3/02A61P3/04A61P3/06A61P3/10A61P9/00A61P9/12A61P35/00A61P37/04A61K2300/00A23V2200/30A23V2200/308A23V2200/324A23V2200/326A23V2200/3262A23V2200/328A23V2200/332A23V2250/208A23V2250/51
Inventor 管轶周粤生朱华晨卢泽菁郑镇钦
Owner 分子态(珠海横琴)中医药健康产业发展有限公司