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Oral-taking rehydration salt, preparation method and applications thereof

A technology of rehydration salt and animal bifidobacteria, which is applied in the field of medicine, can solve the problems of limited treatment of infantile diarrhea, further improvement of diarrhea treatment, and poor defense function of the body, so as to reduce the secretion of water and electrolytes in the intestinal mucosa and significantly treat diarrhea. Effect, the effect of correcting the imbalance of intestinal flora

Pending Publication Date: 2020-04-21
GUANGZHOU BAIYUNSHAN ZHONGYI PHARMA COMPANY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] Although some improvements have been made on oral rehydration salts in the existing technology, the effectiveness of diarrhea treatment still needs to be further improved. The reason should be due to the diversity and complexity of the pathogenesis of infantile diarrhea
Moreover, children's digestive system is not yet fully developed, and the body's defense function is poor. The existing oral rehydration salts have limited therapeutic effects on infantile diarrhea.

Method used

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  • Oral-taking rehydration salt, preparation method and applications thereof
  • Oral-taking rehydration salt, preparation method and applications thereof
  • Oral-taking rehydration salt, preparation method and applications thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0035] Prescription: 0.66 parts by weight of sodium chloride, 0.725 parts by weight of sodium citrate, 0.375 parts by weight of potassium chloride, 3.375 parts by weight of anhydrous glucose, 0.01 parts by weight of zinc gluconate, 0.1 parts by weight of animal bifidobacteria Bb-12 (the content of viable bacteria is about 30 billion CFU / g), 0.755 parts by weight of strawberry fruit powder.

[0036] Preparation:

[0037] (1) Dry the prescription amount of anhydrous dextrose and strawberry fruit powder at a temperature not exceeding 60°C for 2-3 hours, and control the moisture content within 3%; dried anhydrous dextrose and fruit Powder through a 60 mesh sieve;

[0038] (2) Crush the prescription amount of sodium chloride, potassium chloride and sodium citrate through a 60-mesh sieve;

[0039] (3) Thaw the prescription amount of Bifidobacterium animalis Bb-12 to room temperature in advance, and mix it with zinc gluconate to obtain a compound additive;

[0040] (4) Mix the anhydrous gluc...

Embodiment 2

[0042] Prescription: 0.5 parts by weight of sodium chloride, 0.775 parts by weight of sodium citrate, 0.395 parts by weight of potassium chloride, 3.51 parts by weight of anhydrous glucose, 0.02 parts by weight of zinc gluconate, 0.2 parts by weight of animal bifidobacteria Bb-12 (the number of live bacteria is about 30 billion CFU / g), 0.6 parts by weight of strawberry fruit powder.

[0043] The preparation method of the oral replenishing salt solution of this example is the same as that of Example 1, and the obtained composition is named FX2.

Embodiment 3

[0045] Prescription: 0.8 parts by weight of sodium chloride, 0.575 parts by weight of sodium citrate, 0.315 parts by weight of potassium chloride, 3.95 parts by weight of anhydrous glucose, 0.01 parts by weight of zinc gluconate, 0.04 parts by weight of animal bifidobacteria Bb-12 (the content of viable bacteria is about 30 billion CFU / g), 0.31 parts by weight of strawberry fruit powder.

[0046] The preparation method of the oral replenishing salt solution of this example is the same as that of Example 1, and the obtained composition is named FX3.

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Abstract

The invention relates to an oral-taking rehydration salt, which is prepared from the following raw materials in parts by weight: 0.4 to 0.9 part of sodium chloride, 0.5 to 1 part of sodium citrate, 0.2 to 0.6 part of potassium chloride, 2-5 parts of anhydrous dextrose, 0.2 to 1 part of fruit powder, and 0.02 to 0.5 part of a compound additive, wherein the compound additive is prepared by mixing zinc gluconate and bifidobacterium animalis Bb-12. The oral-taking rehydration salt disclosed by the invention has good curative effect on infantile diarrhea.

Description

Technical field [0001] The invention relates to the technical field of medicine, in particular to an oral rehydration salt and its preparation method and application. Background technique [0002] Diarrhea is one of the common diseases with a high incidence in infants and young children, and it is a common and frequently-occurring disease second only to respiratory infections. During diarrhea, the body not only cannot effectively absorb water and electrolytes from food, but also loses them further in the form of intestinal juice. Therefore, during diarrhea, if the water and electrolyte cannot be supplemented in time and effectively, different degrees of dehydration and electrolyte disturbance will occur. [0003] For a long time, the traditional treatment for dehydration caused by diarrhea is intravenous fluids. Intravenous infusion is more harmful, such as reducing the child’s resistance; children’s infusion area is complicated, and it is easy to cause cross-infection between pa...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K35/745A61K47/46A61P1/12A61K33/14A61K31/7004A61K33/30A61K31/194
CPCA61K35/745A61K33/14A61K31/7004A61K31/315A61K31/194A61K47/46A61P1/12A61K2300/00
Inventor 何凤林赵楚文尹震耿春贤邹琦张春波
Owner GUANGZHOU BAIYUNSHAN ZHONGYI PHARMA COMPANY
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