Short-term degradable magnesium alloy material for uterine cavity stent and preparation method

A technology of magnesium alloy and uterine cavity, which is applied in the field of short-term degradable magnesium alloy material and preparation of uterine cavity stent, which can solve the problem of non-degradable uterine cavity stent, achieve excellent biocompatibility, reduce use, and reduce physical pain Effect

Inactive Publication Date: 2020-06-02
TAIYUAN UNIVERSITY OF SCIENCE AND TECHNOLOGY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] In order to solve the problem of secondary operations caused by the non-degradable existing uterine cavity stents, the present invention proposes a component with reasonable design, light weight, high strength, and can degrade and fall off by itself in the uterine cavity environment outside the validity period or Absorption, non-toxic to human body and good biocompatibility, short-term degradable magnesium alloy material for preparing uterine cavity stent and preparation method

Method used

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  • Short-term degradable magnesium alloy material for uterine cavity stent and preparation method
  • Short-term degradable magnesium alloy material for uterine cavity stent and preparation method
  • Short-term degradable magnesium alloy material for uterine cavity stent and preparation method

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Embodiment 1

[0019] The short-term degradable magnesium alloy for preparing uterine cavity stent, its raw material composition and its weight percentage content are: Zn: 6%, Sn: 3%, Ca: 2%, Mn: 1.0%, Cu: 0.5%, and the rest is Mg and unavoidable impurity elements.

[0020] The preparation method of the short-term degradable magnesium alloy for the preparation of the uterine cavity bracket: firstly, the crucible is heated to 530°C, and pure magnesium, pure zinc, and pure tin are put into the crucible of the melting furnace, and a protective atmosphere is introduced at the same time; when the furnace temperature rises to 700 Above ℃, after all the furnace materials are melted, add the remaining metal, stir for two minutes, and keep warm for 15 minutes; after that, keep the preset time, remove the oxide on the surface, and cast into the iron mold metal mold preheated to 280℃. remain balanced.

Embodiment 2

[0022] The short-term degradable magnesium alloy for preparing uterine cavity stent, the preferred raw material composition and its weight percentage content are: Zn: 5%, Sn: 2%, Ca: 1%, Mn: 0.5%, Cu: 0.6%, and the rest is Mg and inevitable impurity elements.

[0023] The preparation method of the short-term degradable magnesium alloy for the preparation of the uterine cavity bracket: firstly, the crucible is heated to 540°C, and pure magnesium, pure zinc, and pure tin are put into the crucible of the melting furnace, and a protective atmosphere is introduced at the same time; when the furnace temperature rises to 720 ℃, after the furnace charge is completely melted, add the remaining metal, stir for two minutes, and keep warm for 10 minutes; after that, keep the preset time, remove the oxide on the surface, and cast it into the iron mold metal mold preheated to 250°C. smooth.

Embodiment 3

[0025] The short-term degradable magnesium alloy for preparing uterine cavity stent, its raw material composition and its weight percentage content are: Zn: 3.0%, Sn: 1.0%, Ca: 3.0%, Mn: 0.8%, Cu: 1.3%, and the rest is Mg and unavoidable impurity elements.

[0026] The preparation method of the short-term degradable magnesium alloy for the preparation of the uterine cavity bracket: firstly, the crucible is heated to 570°C, and pure magnesium, pure zinc, and pure tin are put into the crucible of the melting furnace, and a protective atmosphere is introduced at the same time; when the furnace temperature rises to 710 ℃, after the furnace charge is completely melted, add the remaining metal, stir for two minutes, and keep warm for 20 minutes; after that, keep the preset time, remove the oxide on the surface, and cast it into the iron mold metal mold preheated to 300°C. smooth.

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Abstract

The invention discloses a short-term degradable medical magnesium alloy material for a uterine cavity stent and a preparation method thereof, and belongs to the technical field of medical alloys. Theshort-term degradable medical magnesium alloy material is prepared from the raw materials in percentage by weight: 2-6% of Zn, 0.5-3% of Sn, 0.5-3.0% of Ca, 0.3-1.0% of Mn, 0.5-2% of Cu, and the balance of Mg and inevitable impurity elements, and the sum of weight percentages of all the components is 100%. The invention further discloses the preparation method of the short-term degradable magnesium alloy material. The strength of a magnesium alloy is improved by sufficiently utilizing the action of the elements of calcium, zinc and manganese beneficial to human bodies, surrounding infection ofimplantation materials is restrained by adding copper, the infection rate after operation is reduced, using of antibiotics is reduced, and the medical cost is reduced. The uterine cavity stent prepared by the material can be degraded and absorbed in a body, the histocompatibility is good, reoperation is not needed for taking out the uterine cavity stent, and body pains of patients and the medicalcost are effectively reduced. Meanwhile, enough mechanical strength is achieved, and the mechanical requirements required by supporting a uterine cavity can be met.

Description

technical field [0001] The invention belongs to the technical field of medical alloy materials, and in particular relates to a short-term degradable magnesium alloy material for uterine cavity brackets and a preparation method. Background technique [0002] Intrauterine adhesions refer to a group of diseases caused by partial or total occlusion due to endometrial injury, which can be manifested as abnormal menstruation, infertility, and recurrent miscarriage. After surgical treatment, the recurrence rate of intrauterine adhesions is high, especially in patients with severe intrauterine adhesions, so preventing re-adhesion after surgery is the key to successful treatment. In recent years, intrauterine intrauterine stents have been placed in the uterus to prevent re-adhesion after the resolution of intrauterine adhesions. Currently, intrauterine stents for clinical use or research mainly include contraceptive rings, uterine balloon stents, and Foley balloon stents. These ste...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): C22C23/04A61L31/02C22C1/02
CPCA61L31/022C22C1/02C22C23/04
Inventor 张跃忠刘宝胜任晓霞卫英慧
Owner TAIYUAN UNIVERSITY OF SCIENCE AND TECHNOLOGY
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