A kind of preparation method of L-methionine

Abstract

The invention discloses a preparation method of L-methionine, which comprises the following steps: acetylating DL-methionine to obtain an acetylated product containing N-acetyl-DL-methionine; suction-filtering and collecting the acetylated product The solid matter is dried to obtain the N-acetyl-DL methionine mixture; the N-acetyl-DL methionine mixture is dissolved in absolute ethanol, then suction filtered and the filtrate is collected; the filtrate is subjected to vacuum distillation and the solid matter is collected , to obtain N-acetyl-DL methionine; the N-acetyl-DL methionine is subjected to enzymatic hydrolysis and decolorization treatment to obtain a product solution that generates L-methionine; the product solution is crystallized under reduced pressure and the crystalline solid is collected, and then Using ethanol solution to remove impurities and then dry the crystalline solid to obtain L-methionine. The preparation method of L-methionine provided by the invention improves the purity of L-methionine and improves the optical quality of L-methionine.

Description

technical field

[0001] The invention relates to the technical field of medicine, in particular to a preparation method of L-methionine. Background technique

[0002] Methionine is also known as methionine, and its chemical name is 2-amino-4-methylmercaptobutyric acid. Methionine is an essential amino acid that has important nutritional value for the human body. Methionine maintains the growth and development of the body and nitrogen balance, and has a certain effect on the synthesis of choline and liver fat from adrenaline in medicine; Treatment; Methionine can be used as an adjuvant treatment for poisoning such as sulfonamides, arsenic or benzene, and can also be used as a choleretic. In the feed industry, methionine is one of the most important amino acids necessary for livestock and poultry to synthesize animal protein. It is a fortifier for protein feed and a nutritional additive to make up for the balance of amino acids. Since methionine cannot be synthesized in anima...

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