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42 results about "Aminoacylase" patented technology

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In enzymology, an aminoacylase (EC 3.5.1.14) is an enzyme that catalyzes the chemical reaction...

Modified nucleic acids encoding aspartoacylase (ASPA) and vectors for gene therapy

The present disclosure relates to recombinant nucleic acids and gene therapy vectors comprising modified nucleic acids encoding aspartoacylase (ASPA), and variants thereof, for use in treating diseases and disorders associated with deficiency or dysfunction of ASPA, particularly Canavan disease.

Owner:PFIZER INC