Nucleic acid image fluorescence detecting device integrating virus pretreatment structure

Abstract

The invention provides a nucleic acid image fluorescence detecting device integrating a virus pretreatment structure. The nucleic acid image fluorescence detecting device comprises a sampling structure, a nucleic acid pretreating structure, a micro-fluidic structure having liquid drop driving capacity and a fluorescence detecting image sensor structure, wherein the nucleic acid pretreating structure comprises a sample diluting and diffusion chamber and a centrifugal separation and chromatography chamber; the micro-fluidic structure having the liquid drop driving capacity comprises a reagent accommodating cavity and a micro-fluidic chip; and the micro-fluidic chip is PDMS-glass. The nucleic acid image fluorescence detecting device disclosed by the invention has the beneficial effects that astanding virus detecting device can be realized, so that corona viruses can be inspected through expiration, and the detection cost is reduced; and the nucleic acid image fluorescence detecting device contributes to miniaturization of gene sequencing equipment and universalness of sequencing projects, so that more hospitals have all inspection conditions and space for development of gene sequencing business, requirements of more client are met, more people can burden the expense of gene sequencing, the medical care level of people is improved, and the nucleic acid image fluorescence detectingdevice has great significance in coping with epidemic situations possibly appearing in the future.

Description

technical field [0001] The main subject fields of the present invention are: first-level subject: electronics and communication technology; second-level subject semiconductor technology. The associated subject areas are: first-level discipline: preventive medicine and public health; second-level discipline: epidemiology. The high-tech field is: biology and population health technology; the high-tech sub-field is: medical instrument, equipment and medical special software technology field, especially a nucleic acid image fluorescence detection device integrated with a virus preprocessing structure. Background technique [0002] For most known and undiscovered coronaviruses, ordinary real-time quantitative fluorescent PCR nucleic acid detection reagents have played an important role, but due to the limitations of cumbersome operations, long time-consuming, and the need for centralized inspection, they cannot meet the requirements of a large number of suspected patients and car...

AI Technical Summary

Problems solved by technology

[0002] For most known and undiscovered coronaviruses, ordinary real-time quantitative fluorescent PCR nucleic acid detection reagents have played an important role, but due to the limitations of cumbersome operations, long time-consuming, and the need for centralized inspection, they cannot meet the needs of a large number of suspected patients and carry them during the incubation period. Testing needs for screening and diagnosis of infected persons and asymptomatic infected persons

Patients flock to fever clinics in hospitals, which not only causes ineffective occupation of medical resources, but also greatly increases the risk of cross-infection

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