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Data analysis method, device and equipment and storage medium

A technology for data analysis and sequencing data, applied in the field of biology, can solve problems such as background deviation, achieve accurate detection, expand sensitivity and completeness

Pending Publication Date: 2020-06-23
GENEWIZ INC SZ
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, there is a little background bias when dealing with different combinations of the same data

Method used

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  • Data analysis method, device and equipment and storage medium
  • Data analysis method, device and equipment and storage medium
  • Data analysis method, device and equipment and storage medium

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0025] figure 1 It is a flow chart of a data analysis method provided by Embodiment 1 of the present invention. This embodiment is applicable to data analysis. The method can be executed by the data analysis device in the embodiment of the present invention. The device can use software and / or or hardware implementation, such as figure 1 As shown, the method specifically includes the following steps:

[0026] S110, read the sequencing data of at least one sample.

[0027] Wherein, the sequencing data includes at least one read, and each read corresponds to a base sequence fragment.

[0028] Specifically, read the sequencing data of at least one sample, for example, we need to detect three samples M01, M02, and M03, and the bacterial composition and proportion of the three samples are known (see Beiresources Catalog: HM-782D for details) . After sequencing, the data composition of the three samples M01, M02, and M03 contained 38,386, 68,436, and 31,791 base sequences (reads)...

Embodiment 2

[0062] figure 2 It is a schematic structural diagram of a data analysis device provided in Embodiment 2 of the present invention. This embodiment can be applied to the situation of data analysis, and the device can be implemented in the form of software and / or hardware, and the device can be integrated in any device that provides the function of data analysis, such as figure 2 As shown, the data analysis device specifically includes: a reading module 210 , a determination module 220 , a statistics module 230 and an analysis module 240 .

[0063] Wherein, the reading module 210 is used to read the sequencing data of at least one sample;

[0064] A determining module 220, configured to determine a representative sequence according to the sequencing data;

[0065] A statistical module 230, configured to count the depth information of the representative sequence in each sample;

[0066] The analysis module 240 is configured to analyze the representative sequence and the depth...

Embodiment 3

[0070] image 3 It is a schematic structural diagram of a computer device in Embodiment 4 of the present invention. image 3 A block diagram of an exemplary computer device 12 suitable for implementing embodiments of the invention is shown. image 3 The computer device 12 shown is only an example, and should not impose any limitation on the functions and scope of use of the embodiments of the present invention.

[0071] Such as image 3 As shown, computer device 12 takes the form of a general-purpose computing device. Components of computer device 12 may include, but are not limited to: one or more processors or processing units 16 , system memory 28 , bus 18 connecting various system components including system memory 28 and processing unit 16 .

[0072] Bus 18 represents one or more of several types of bus structures, including a memory bus or memory controller, a peripheral bus, an accelerated graphics port, a processor, or a local bus using any of a variety of bus struc...

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Abstract

The invention discloses a data analysis method, device and equipment and a storage medium. The method comprises the following steps: reading sequencing data of at least one sample; determining a representative sequence according to the sequencing data; counting depth information of the representative sequence in each sample; and analyzing the representative sequence and the depth information of the representative sequence in each sample. Through the technical scheme of the invention, the components can be detected more completely and accurately, and the detection sensitivity and integrity areexpanded.

Description

technical field [0001] Embodiments of the present invention relate to the field of biology, and in particular, to a data analysis method, device, device, and storage medium. Background technique [0002] With the development of metagenomics, researchers can accurately analyze the diversity of human microbiota, and extend to immunity, metabolism, mental behavior, and the relationship between various health and disease states and the balance of human microbiota. Metagenomics analysis has become the main means of microbial population research. The huge sequence information obtained through high-throughput sequencing, using bioinformatics analysis, studies the composition, diversity, and relationship with the environment of microorganisms, which promotes the research of microorganisms. Entered a new era. [0003] 16SrDNA sequencing technology is one of the main technologies for studying metagenomics. In the early days of the rise of technology, the main purpose of the bioinfor...

Claims

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Application Information

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IPC IPC(8): G16B20/30
CPCG16B20/30
Inventor 贾瑞凯叶桦方其张艳吴昕廖国娟
Owner GENEWIZ INC SZ
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