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Traditional Chinese medicine oral liquid for preventing aquatic hepatobiliary syndrome and preparation method of oral liquid

A technology for traditional Chinese medicine oral liquid and hepatobiliary syndrome, which is applied in the directions of pharmaceutical formulations, medical preparations containing active ingredients, drug combinations, etc. Effect

Inactive Publication Date: 2020-07-03
WUHAN HUAYANG ANIMAL PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] In order to overcome the deficiencies in the above-mentioned prior art, the object of the present invention is to provide a traditional Chinese medicine oral liquid for preventing aquatic hepatobiliary syndrome and a preparation method thereof, which not only solves the problem of cumbersome operation in clinical practice, but also Improve the absorption and utilization of drugs in animals

Method used

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  • Traditional Chinese medicine oral liquid for preventing aquatic hepatobiliary syndrome and preparation method of oral liquid
  • Traditional Chinese medicine oral liquid for preventing aquatic hepatobiliary syndrome and preparation method of oral liquid
  • Traditional Chinese medicine oral liquid for preventing aquatic hepatobiliary syndrome and preparation method of oral liquid

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Embodiment 1

[0026] This embodiment provides a traditional Chinese medicine oral liquid for preventing aquatic hepatobiliary syndrome, including the following components in terms of parts by mass: 35 parts of extract concentrates mixed with turmeric and turmeric, 15 parts of Acanthopanax extract concentrates 0.5 parts of volatile oil extracted by mixing turmeric, turmeric and turmeric, 802.8 parts of Span and 20 parts of fatty alcohol polyoxyethylene ether (AEO-9).

[0027] The preparation method of above-mentioned Chinese medicine oral liquid comprises the steps:

[0028] 1) After mixing turmeric and turmeric at a ratio of 1:1, extract it with 75% ethanol at 65°C (drug solution ratio = 1:10), extract 3 times, each time for 1.5h, and collect turmeric and turmeric. Volatile oil; the extract is centrifuged and concentrated to obtain the extract concentrate obtained by the mixed extraction of turmeric and turmeric;

[0029] 2) Extract Acanthopanax at 65° C. with 55% ethanol (drug solution ra...

Embodiment 2

[0033] This embodiment provides a traditional Chinese medicine oral liquid for preventing aquatic hepatobiliary syndrome, including the following components in terms of mass parts: 30 parts of extract concentrates mixed with turmeric and turmeric, 10 parts of Acanthopanax extract concentrates 0.3 parts of volatile oil extracted from turmeric, turmeric and turmeric, 2.5 parts of glycerin and 10 parts of nonylphenol polyoxyethylene ether (NP-10).

[0034] The preparation method of above-mentioned Chinese medicine oral liquid comprises the steps:

[0035] 1) After mixing turmeric and turmeric at a ratio of 1:1, extract it with 75% ethanol at 55°C (drug-solution ratio = 1:8), extract 3 times, each time for 1.5h, and collect turmeric and turmeric. Volatile oil; the extract is centrifuged and concentrated to obtain the extract concentrate obtained by the mixed extraction of turmeric and turmeric;

[0036] 2) Extracting Acanthopanax senticosus using 55% ethanol at 55°C (drug solutio...

Embodiment 3

[0040] This embodiment provides a traditional Chinese medicine oral liquid for preventing aquatic hepatobiliary syndrome, including the following components in terms of parts by mass: 40 parts of extract concentrates mixed with turmeric and turmeric, 20 parts of Acanthopanax extract concentrates 1 part of volatile oil mixed with turmeric and turmeric, 803 parts of Span and 25 parts of polyoxyethylene hydrogenated castor oil (RH 40).

[0041] The preparation method of above-mentioned Chinese medicine oral liquid comprises the steps:

[0042]1) After mixing turmeric and turmeric at a ratio of 1:2, extract it with 75% ethanol at 60°C (medicine-solution ratio = 1:10), extract 3 times, each time for 1.5h, and collect turmeric and turmeric. Volatile oil; the extract is centrifuged and concentrated to obtain the extract concentrate obtained by the mixed extraction of turmeric and turmeric;

[0043] 2) Extracting Acanthopanax senticosus using 55% ethanol at 60°C (drug solution ratio ...

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Abstract

The invention belongs to the technical field of aquatic medicines, and in particular relates to a traditional Chinese medicine oral liquid for preventing aquatic hepatobiliary syndrome. The oral liquid includes the following components in parts by mass: 30-40 parts of a radix curcumae and rhizome curcumae longae mixed extract concentrated liquid, 10-20 parts of a root and vine of manyprickle acanthopanax extract concentrated liquid, 0.3-1 part of radix curcumae and rhizome curcumae longae mixed extract volatile oil, 2.5-3 parts of a co-surfactant, and 10-25 parts of a surfactant. A preparationmethod of the oral liquid comprises the following steps: step 1), mixing radix curcumae and rhizome curcumae longae, and performing extraction to obtain the radix curcumae and rhizome curcumae longaemixed extract volatile oil and the radix curcumae and rhizome curcumae longae mixed extract concentrated liquid; step 2), performing extraction on root and vine of manyprickle acanthopanax to obtainthe root and vine of manyprickle acanthopanax extract concentrated liquid; and step 3) mixing the extract concentrated liquids obtained in the step 1) and the step 2), and uniformly mixing the obtained mixture, the radix curcumae and rhizome curcumae longae mixed extract volatile oil, the co-surfactant and the surfactant fully under stirring. The traditional Chinese medicine oral liquid provided by the invention not only reduces the labor cost of clinical use, but also improves the absorption and utilization of the medicine in aquatic animals.

Description

technical field [0001] The invention belongs to the technical field of aquatic medicines, and in particular relates to a traditional Chinese medicine oral liquid for preventing aquatic hepatobiliary syndrome and a preparation method thereof. Background technique [0002] At present, high-density and intensive aquaculture is the main aquaculture method in my country today. However, in order to save costs and obtain higher economic benefits, farmers often adopt non-standard methods and measures, such as keeping the water environment clean for a long time, blindly increasing the stocking density, ignoring the nutritional balance and safety and hygiene of the feed, and randomly Applying drugs and increasing the frequency of application, etc. As a result, the internal and external environment of farmed fish is out of balance, which affects the health of fish and threatens its life. In recent years, various syndromes have frequently occurred in various farmed animals in aquacult...

Claims

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Application Information

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IPC IPC(8): A61K36/9066A61P1/16
CPCA61K9/0095A61K36/254A61K36/9066A61K2236/333A61K2236/39A61P1/16A61K2300/00
Inventor 肖飞马立保高贤涛王静夏露吴艳丽
Owner WUHAN HUAYANG ANIMAL PHARMA