Low-temperature phase-change heat exchanger applied to cell vitrification
A vitrification freezing and low-temperature phase change technology, applied in indirect heat exchangers, lighting and heating equipment, etc., can solve the problem of single driving force, improve the temperature uniformity, strengthen the flow heat transfer process, and reduce the cell's damage effect
Active Publication Date: 2020-07-28
SOUTHEAST UNIV
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Problems solved by technology
Aiming at the single driving force of the pulsating heat pipe, and considering the working temperature range of cell vitrification
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[0023] Further description below in conjunction with accompanying drawing:
[0024] figure 1It is a system diagram of a low-temperature phase-change heat exchanger applied to cell vitrification in the present invention. As shown in the figure, the system includes a silicon-based continuous contraction-expanding plate-type pulsating heat pipe, a cell suspension storage device, a heating device, and a condensation box. The evaporating section of the silicon-based continuous shrinking-expanding plate-type pulsating heat pipe 2 is fixed in the outer shell of the heating device 4, the condensation section of the silicon-based continuous shrinking-expanding plate-type pulsating heat pipe 2 is fixed in the condensation box 1, and the cell suspension holding device 3 is coupled On the upper surface of the silicon-based continuous contraction-expansion plate type pulsating heat pipe 2 . During operation, the heating device 4 inputs heat load to the evaporation section of the silicon-...
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The invention discloses a low-temperature phase-change heat exchanger applied to cell vitrification. The low-temperature phase-change heat exchanger applied to the cell vitrification comprises a pulsating heat pipe, a cell suspension holding device, a heating device and a condensation box, wherein the pulsating heat pipe is a silicon-based continuously-contracting-expanding plate-type pulsating heat pipe, and comprises a heat pipe base body and a continuously-contracting-expanding snake-shaped groove formed in the heat pipe base body; and the width d of the continuously-contracting-expanding snake-shaped groove presents continuous linear periodic change, d is not less than 1 and not greater than d2, the continuous linear change period of the width d of the groove is n from any one elbow outlet of the continuously-contracting-expanding snake-shaped groove to the next elbow inlet in a fixed direction, and n is an integer of not less than 2. The low-temperature phase-change heat exchangeris applied to the cell vitrification, that is, is capable of reaching an ultra-high cooling speed needed for the vitrification, and realizing replacement for a high-concentration cryoprotectant by alow-concentration cryoprotectant, so that the damage of the cell vitrification to cells is reduced.
Description
technical field [0001] The present invention relates to the field of phase change heat technology, and specifically relates to a low-temperature phase heat pipe mainly composed of plate-type pulsating heat pipes with continuous contraction-expansion serpentine channels designed to meet the needs of ultra-fast heat exchange in a short period of time. Change heat. Background technique [0002] Cell cryopreservation is the main tool for preserving and propagating genetically superior animals and plants, and is also an important technical means for preserving animal germplasm resources. It can provide a wider range of background materials for reproductive technologies such as in vitro fertilization, nuclear transfer, and transgenics. The cryopreservation of cells is to gradually lower their temperature to ultra-low temperature (-196°C), and then freeze them in liquid nitrogen to reduce cell metabolism and store them stably for a long time. According to the different cooling rat...
Claims
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IPC IPC(8): F28D15/04
CPCF28D15/046
Inventor 陈永平肖念何刘向东郑毅
Owner SOUTHEAST UNIV