Low-temperature phase-change heat exchanger applied to cell vitrification

Abstract

The invention discloses a low-temperature phase-change heat exchanger applied to cell vitrification. The low-temperature phase-change heat exchanger applied to the cell vitrification comprises a pulsating heat pipe, a cell suspension holding device, a heating device and a condensation box, wherein the pulsating heat pipe is a silicon-based continuously-contracting-expanding plate-type pulsating heat pipe, and comprises a heat pipe base body and a continuously-contracting-expanding snake-shaped groove formed in the heat pipe base body; and the width d of the continuously-contracting-expanding snake-shaped groove presents continuous linear periodic change, d is not less than 1 and not greater than d2, the continuous linear change period of the width d of the groove is n from any one elbow outlet of the continuously-contracting-expanding snake-shaped groove to the next elbow inlet in a fixed direction, and n is an integer of not less than 2. The low-temperature phase-change heat exchangeris applied to the cell vitrification, that is, is capable of reaching an ultra-high cooling speed needed for the vitrification, and realizing replacement for a high-concentration cryoprotectant by alow-concentration cryoprotectant, so that the damage of the cell vitrification to cells is reduced.

Description

technical field [0001] The present invention relates to the field of phase change heat technology, and specifically relates to a low-temperature phase heat pipe mainly composed of plate-type pulsating heat pipes with continuous contraction-expansion serpentine channels designed to meet the needs of ultra-fast heat exchange in a short period of time. Change heat. Background technique [0002] Cell cryopreservation is the main tool for preserving and propagating genetically superior animals and plants, and is also an important technical means for preserving animal germplasm resources. It can provide a wider range of background materials for reproductive technologies such as in vitro fertilization, nuclear transfer, and transgenics. The cryopreservation of cells is to gradually lower their temperature to ultra-low temperature (-196°C), and then freeze them in liquid nitrogen to reduce cell metabolism and store them stably for a long time. According to the different cooling rat...

AI Technical Summary

Problems solved by technology

Aiming at the single driving force of the pulsating heat pipe, and considering the working temperature range of cell vitrification

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