Anti-slip and anti-stenosis esophageal stent with mesoporous structure

Abstract

The invention relates to an anti-slip and anti-stenosis esophageal stent with a mesoporous structure, and belongs to the technical field of medical instruments. The stent comprises a covered stent, acovered stent outer surface coating and a mesoporous material. Polymer fibers / yarns and metal wires are woven into a covered stent at one time by adopting a 128-spindle or more-spindle weaving machine, the outer surface of the covered stent is coated with a degradable medical polymer material by adopting a coating method to form a random micro-patterns, and the mesopores in the tube wall of the integrated covered stent are filled with the random micro-patterns. The degradable medical polymer material is blended with a drug capable of inhibiting tissue proliferation. The esophageal stent disclosed by the invention has a controllable mesoporous structure and can provide excellent slip resistance and stenosis resistance. The mesoporous structure, the random micro-morphology of the outer surface coating and the application of the drug for inhibiting tissue hyperplasia provide dual effects for the anti-slip and anti-stenosis functions of the esophageal stent. The process is simple, the production is easy to standardize and automate, and the application prospect is wide.

Description

technical field [0001] The invention relates to an anti-slip and anti-stenosis esophageal stent with a mesoporous structure, which belongs to the technical field of medical devices. Background technique [0002] The esophagus is a part of the digestive tract. It connects to the pharynx at the top and leads to the stomach at the bottom. It is about 25 cm long. Esophageal stricture is a clinically common symptom of digestive system diseases. It is a local tissue hyperplasia of the esophagus caused by benign esophageal strictures (such as strictures after chemical caustic burns, congenital strictures of the esophagus, etc.) and malignant esophageal cancer. Esophageal strictures can lead to obstruction of a patient's esophagus, which can lead to difficulty swallowing and even respiratory failure. In 2018, there were more than 572,000 patients with esophageal cancer worldwide, the mortality rate reached 89%, and the five-year survival rate was only 10%-15%. At present, esophage...

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Problems solved by technology

However, the smooth silicone film brings the problem of slippage of the covered stent

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