Multi-frequency multi-power ultrasonic microbubble noninvasive transdermal drug administration treatment and real-time ultrasonic visualized monitoring system

Abstract

The invention discloses a multi-frequency multi-power ultrasonic microbubble noninvasive transdermal drug administration treatment and real-time ultrasonic visualized monitoring system. The system comprises an ultrasonic transdermal drug administration system, an ultrasonic visualized monitoring system and an ultrasonic electronic control system, wherein the ultrasonic transdermal drug administration system comprises a signal generator, an ultrasonic transducer and an ultrasonic microbubble transdermal drug administration device; and the ultrasonic visualized monitoring system comprises a time-gain compensating circuit, a filter sequence, a power amplification array, an efficient noise amplifier and an ultrasonic imaging monitoring probe. According to the multi-frequency multi-power ultrasonic microbubble noninvasive transdermal drug administration treatment and real-time ultrasonic visualized monitoring system, through dual-frequency design of the ultrasonic transducer, single frequency deficiency is overcome; outputting of dual-frequency ultrasound is achieved through accurately driving the transducer by the ultrasonic electronic control system; and through the ultrasonic visualized monitoring system and the ultrasonic microbubble transdermal drug administration device, ultrasonic therapy and transdermal drug administration under the condition of real-time navigation and monitoring are achieved, and the efficiency and accuracy of drug administration are improved.

Description

technical field [0001] The invention relates to the field of ultrasonic therapy, more specifically, to a multi-frequency and multi-power ultrasonic microbubble non-invasive transdermal drug delivery treatment and a real-time ultrasonic visualization monitoring system. Background technique [0002] Ultrasound, as a mechanical wave, has been used in rehabilitation medicine for decades, and it still plays an important role in treating soft tissue injuries, promoting nerve regeneration, and releasing scars. Because ultrasonic radiation will not destroy the activity of drugs, it has obvious effect of promoting the penetration of fat-soluble and water-soluble drugs including biomacromolecules, and can reach the deep tissue of the skin. Research on skin drug delivery systems is in full swing. [0003] In the past few decades, 800kHz continuous wave was mostly used in ultrasound therapy. In recent years, the application of 1-3MHz high-frequency ultrasound and 20-50kHz low-frequency...

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Problems solved by technology

[0005] In order to overcome the defects of single ultrasonic treatment frequency, blindness in treatment effect and low efficiency of ultrasonic administration in the above-mentioned prior art, the present invention provides a multi-frequency and multi-power ultrasonic microbubble non-invasive transdermal drug delivery treatment and real-time ultrasonic visualization monitoring system

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