Semi-bionic extraction preparation method of pomegranate peel formula granules

Abstract

The invention belongs to the technical field of semi-bionic extraction, and discloses a semi-bionic extraction preparation method of pomegranate peel formula granules. A U9(91x33) uniform design tableis adopted for the first time, ellagic acid, gallic acid, total phenol and dry extract are taken as determination indexes, an analytic hierarchy process (AHP), a criteria importance through intercriteria correlation (CRITIC) method and an AHP-CRITIC mixed weighting method are adopted, and standardization processing and comprehensive evaluation are carried out on index values, so that pomegranatepeel semi-bionic optimal process parameters are predicted. The optimization conditions of the method are as follows: the pH values of water for three times of decoction are 6.0, 7.4 and 9.0 in sequence, the total decoction time is 4 hours, the semi-bionic extraction process parameters of pomegranate peel optimized by adopting uniform design are reasonable, and the process is feasible by verification. According to the pomegranate peel formula granules prepared by the semi-bionic extraction method, the content of effective components is greatly increased, the bioavailability is higher, and the pomegranate peel formula granules are more suitable for being absorbed by the human body.

Description

technical field [0001] The invention belongs to the technical field of semi-bionic extraction, in particular to a preparation method for semi-bionic extraction of pomegranate peel formula granules. Background technique [0002] Currently, pomegranate peel is the dried peel of the pomegranate. Pomegranate (Punica granatum L.) belongs to the deciduous shrub or small tree of the Pomegranate family. The roots, leaves, flowers, fruits, and seeds of pomegranate contain a variety of physiologically active components, including polyphenols, flavonoids, alkaloids, and organic acids, and the polyphenols are mainly concentrated in the pomegranate peel. [0003] The 2015 edition of "Chinese Pharmacopoeia" included pomegranate peel as a traditional Chinese medicine. Pomegranate peel has a slight odor and a bitter taste. After being processed and fried with charcoal, it is warm in nature and returns to the large intestine meridian. Pomegranate peel polyphenols have anti-oxidation, antib...

AI Technical Summary

Problems solved by technology

[0006] To sum up, the problems existing in the prior art are: traditional water decoction and extraction of pomegranate peel, low extraction rate of active components of small molecules, low amount of extract, which leads to weak medicinal effect and high cost of preparing formula granules

Images