The invention relates to a preparation method of flame-retardant, impact-resistant and high-fluidity chloroethylene-based special resin, and belongs to the field of modification of functional polymer materials. The preparation method comprises the following process steps of (1) adding deionized water, an initiator A, an emulsifier, a co-emulsifier, a dispersing agent, a soft monomer and a crosslinking agent into a reaction kettle at 30 DEG C while stirring, pre-emulsifying the resulting solution to obtain a pre-emulsified solution; (2) increasing the temperature of the pre-emulsified solution to be not greater than 90 DEG C, and carrying out reaction while keeping the temperature to obtain a soft monomer kernel emulsion; and (3) adding a chloroethylene-based monomer, styrene, the soft monomer kernel emulsion, an initiator B, the deionized water, and the dispersing agent into the reaction kettle and carrying out reaction while keeping the temperature at 30-70 DEG C to obtain the special resin. Compared with acrylonitrile-butadiene-styrene copolymer (ABS), the chloroethylene-based special resin has the advantages of low price, self flame retardance, high toughness and the like, and can be used for completely replacing ABS and the flame-retardant ABS to be widely applied to the fields of airplanes, cars, ships, household appliances, building materials and the like.