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Traditional Chinese medicine composition and application thereof in preparing medicines for preventing and/or treating diabetes mellitus

A composition and technology of traditional Chinese medicine, applied in the field of medicine, can solve the problems of drug resistance, increase of drug resistance, and long treatment cycle, etc., and achieve the effect of low cost, small side effects, and improvement of insulin resistance

Active Publication Date: 2020-10-13
李赛美
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] At present, the drugs used to treat diabetes include: insulin and its analogs, sulfonylurea secretagogues, metformin, α-glucosidase inhibitors, thiazolidinedione derivatives sensitizers, fennelic acid Derivative secretagogues, GLP-1 receptor agonists and DPP-4 enzyme inhibitors, etc., but the treatment cycle of these drugs is relatively long, and some may have toxic side effects
In addition, due to the complex causes of diabetes and the complementarity of disease pathways, drug resistance is prone to occur. At the same time, long-term use of a single drug will also cause gene mutations, resulting in a sharp increase in the probability of drug resistance

Method used

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  • Traditional Chinese medicine composition and application thereof in preparing medicines for preventing and/or treating diabetes mellitus
  • Traditional Chinese medicine composition and application thereof in preparing medicines for preventing and/or treating diabetes mellitus
  • Traditional Chinese medicine composition and application thereof in preparing medicines for preventing and/or treating diabetes mellitus

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Effect test

Embodiment 1

[0043] This embodiment provides a kind of traditional Chinese medicine composition, and its prescription of each dose is: Dried ginger 6g, Scutellaria baicalensis 10g, Coptis 9g, Codonopsis 10g, Poria 10g, Atractylodes 10g, Cassia 6g, Radix Paeoniae Rubra 10g, Pueraria 15g, Rhubarb 6g, Corn silk 10g, gypsum 15g, red koji decoction pieces 5g and stevia decoction pieces 1g.

[0044] The preparation method of the traditional Chinese medicine composition is as follows: take dried ginger, scutellaria baicalensis, coptis, Codonopsis pilosula, Poria cocos, herb atractylodes, cinnamon, red peony root, kudzu root, rhubarb, corn silk and gypsum, wash, remove impurities, dry at 40°C, grind them, add Decoct with 10 times the weight of water for 1 hour, then filter with a 200-mesh filter, spray-dry the filtrate to obtain extract A; take red yeast and stevia decoction pieces, add 500mL water to decoct to 250mL, then add extract A, After dissolving, it is filtered with a 200-mesh filter, the...

Embodiment 2

[0049] This embodiment provides a tablet for treating diabetes, which contains dried ginger, baicalin, coptis, codonopsis, poria, herb, cinnamon, red peony root, kudzu root, rhubarb, corn silk, gypsum, red koji decoction pieces and stevia decoction pieces The prepared traditional Chinese medicine composition and pharmaceutically acceptable auxiliary materials. The tablet is administered orally, 1 to 3 times a day. According to the dosage of raw materials, the daily dose is: dried ginger 12g, baicalin 20g, coptis 18g, codonopsis 20g, poria 20g, atractylodes 20g, cinnamon 12g, red peony root 20g, kudzu root 30g, rhubarb 12g, corn silk 20g, gypsum 30g , 10g of red koji decoction pieces and 2g of stevia decoction pieces. The preparation method of Chinese medicine composition refers to embodiment 1.

Embodiment 3

[0051] The present embodiment provides a capsule for the treatment of diabetes, which contains dried ginger, scutellaria baicalensis, coptis, Codonopsis pilosula, Poria cocos, herb atractylodes, cinnamon, red peony root, kudzu root, rhubarb, corn silk, gypsum, red yeast rice pieces and stevia leaf pieces The prepared traditional Chinese medicine composition and pharmaceutically acceptable auxiliary materials. The capsule is administered orally, 1 to 3 times a day. According to the dosage of raw materials, the daily dose is: dried ginger 12g, baicalin 20g, coptis 18g, codonopsis 20g, poria 20g, atractylodes 20g, cinnamon 12g, red peony root 20g, kudzu root 30g, rhubarb 12g, corn silk 20g, gypsum 30g , 10g of red koji decoction pieces and 2g of stevia decoction pieces. The preparation method of Chinese medicine composition refers to embodiment 1.

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Abstract

The invention discloses a traditional Chinese medicine composition which contains dried ginger, radix scutellariae, rhizoma coptidis, radix codonopsis, poria cocos, rhizoma atractylodis, cinnamon, radix paeoniae rubra, radix puerariae, radix et rhizoma rhei, corn stigma, gypsum, red yeast rice and stevia rebaudiana. The invention also discloses an application of the traditional Chinese medicine composition in preparation of medicines for preventing and / or treating diabetes mellitus. Monitoring of oral glucose tolerance, glycosylated hemoglobin, insulin resistance levels and pancreatic beta cell functions of diabetic patients proves that the traditional Chinese medicine composition has the treatment effects of reducing the blood sugar of the diabetic patients, improving the pancreatic function of the patients and recovering the sensitivity of organisms to insulin.

Description

technical field [0001] The invention belongs to the technical field of medicine, and in particular relates to a traditional Chinese medicine composition and its use in preparing medicines for preventing and / or treating diabetes. Background technique [0002] Diabetes is one of the common chronic non-communicable diseases. The "Global Diabetes Overview" released by the International Diabetes Federation in 2019 shows that as of 2019, the number of adults with diabetes worldwide has tripled in the past 40 years, and has increased to 422 million people, accounting for 8.5% of the total global population. Among them, the report specifically pointed out that the incidence of diabetes in my country has grown "explosively" in the past few decades. So far, the prevalence of diabetes among adults in my country is close to 10%, which has posed a great threat to national health and economic development. [0003] At present, the drugs used to treat diabetes include: insulin and its anal...

Claims

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Application Information

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IPC IPC(8): A61K36/9068A61P3/10A61P3/06A61P5/50A61K33/06
CPCA61K36/9068A61K36/539A61K36/718A61K36/344A61K36/076A61K36/284A61K36/54A61K36/71A61K36/65A61K36/488A61K36/708A61K36/899A61K33/06A61K36/062A61K36/287A61P3/10A61P3/06A61P5/50A61K2236/19A61K2236/331A61K2236/51A61K2300/00
Inventor 李赛美徐越清徐鸣
Owner 李赛美
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