Method for selectively synthesizing N-alkylaminodipropionate solution

Abstract

The invention belongs to the technical field of organic synthesis and particularly discloses a method for selectively synthesizing an N-alkylaminodipropionate solution. The method comprises the following steps: with akyl primary amine and acrylate as raw materials, dissolving acrylate in an organic solvent to prepare an acrylate solution; dropwise adding alkyl primary amine into the acrylate solution so as to allow a reaction to be implemented in a direction of generating N-alkylamino dipropionic ester; and adding an aqueous solution of alkali metal hydroxide to convert N-alkylamino dipropionic ester into N-alkylaminodipropionate, and carrying out reduced-pressure distillation to remove the organic solvent in order to realize selective synthesis of N-alkylaminodipropionate. According to the method, high-purity N-alkylaminodipropionate can be obtained, and an impurity content can be reduced to 5% or below; high temperature, high pressure and complex crystallization and purification steps are not needed, so the method is simple and feasible; and the used raw materials and solvents can be recycled, so the method is very energy-saving and environment-friendly.

Description

technical field [0001] The invention belongs to the technical field of organic synthesis, and in particular relates to a method for selectively synthesizing N-alkylaminodipropionate solution. Background technique [0002] N-Alkylaminopropionates and N-Alkylaminodipropionates are two types of very useful surfactants, which are widely used as cleaning agents, emulsifiers, flotation agents and electroplating additives, etc. At present, the synthesis of these two types of compounds is basically obtained by converting fatty amines and α, β-unsaturated acids, nitriles or esters under certain conditions, but the reaction products are mixed with N-alkylaminopropionate and N-alkylaminodi Propionate, and due to the difference in the hydrophilic and lipophilic properties of N-alkylaminopropionate and N-alkylaminodipropionate and the wide application in daily chemicals such as household detergents and cosmetics, selectivity is required Both types of material were prepared in high purit...

AI Technical Summary

Problems solved by technology

[0003] At present, there is no method to generate high-purity N-alkylaminopropionate or N-alkylaminodipropionate, and for the selective generation of N - There are many studies on alkyl aminopropionate (such as US2468012, US2816911); US patent US5922909 introduces the ratio of N-alkylaminopropionate and N-alkylaminodipropionate by controlling the pH of the reaction method, but its adjustment range is not large, and it is impossible to achieve an absolute advantage

Therefore, existing synthetic method is difficult to obtain N-alkylaminodipropionate alone