An antibacterial surface with "anti-fouling-sterilization-release" multifunctional response and its preparation method
A multi-functional and responsive technology, which can be used in biocide-containing paints, antifouling/underwater coatings, coatings, etc., to solve the problems that bacteria cannot be desorbed and dead bacteria cannot be removed, and achieves a simple and efficient preparation method. Long-lasting anti-bacterial adhesion and killing effect, expanding the application range
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Embodiment 1
[0038]Add 0.8g of N-isopropylacrylamide (NIPAM) into a 250mL round bottom flask, then add 0.2g of sulfobetaine methacrylate (SBMA), dissolve the drug completely with 100mL of deionized water, and continue to add 0.05g of N , N'-methylenebisacrylamide (MBAA), finally add 0.05g initiator potassium persulfate (KPS), pass N 2 30 min, and the whole process was carried out in an ice-water bath. However, after the passage, the temperature of the water bath was raised to 75°C and reacted for 5 hours to obtain a pure white turbid liquid, the product NIPAM / SBMA microgel, which was dialyzed in deionized water for 3 days to remove some small molecular impurities and obtain antifouling -Release the microgel spheres and observe their surface morphology with a scanning electron microscope (SEM), the results are as follows figure 2 As shown, the particles are uniform.
[0039] Tannic acid (TA) and Fe 3+ Collaborative assembly and microgel deposition on silicon wafers, first configure 20m...
Embodiment 2
[0041] Add 0.9g of N-isopropylacrylamide (NIPAM) into a 250mL round bottom flask, then add 0.1g of sulfobetaine methacrylate (SBMA), dissolve the drug completely with 100mL of deionized water, and continue to add 0.05g of N , N'-methylenebisacrylamide (MBAA), finally add 0.05g potassium persulfate (KPS), pass N 2 30 min, and the whole process was carried out in an ice-water bath. However, after the passage, the temperature of the water bath was raised to 75°C and reacted for 5 hours to obtain a pure white turbid liquid, the product NIPAM / SBMA microgel, which was dialyzed in deionized water for 3 days to remove some small molecular impurities and obtain antifouling - Releases microgel balls.
[0042] Tannic acid (TA) and Fe 3+ Collaborative assembly and microgel deposition on silicon wafers, first configure 20mL buffer solution containing 100mg microgel beads, 87.7mg NaCl, 340.2mg TA and 54mg Fe 3+ The solution was added to the silicon chip, the liquid level was not over th...
Embodiment 3
[0044] Add 0.7g of N-isopropylacrylamide (NIPAM) into a 250mL round bottom flask, then add 0.3g of sulfobetaine methacrylate (SBMA), dissolve the drug completely with 100mL of deionized water, and continue to add 0.05g of N , N'-methylenebisacrylamide (MBAA), finally add 0.05g potassium persulfate (KPS), pass N 2 30 min, and the whole process was carried out in an ice-water bath. However, after the passage, the temperature of the water bath was raised to 75°C and reacted for 5 hours to obtain a pure white turbid liquid, the product NIPAM / SBMA microgel, which was dialyzed in deionized water for 3 days to remove some small molecular impurities and obtain antifouling - Releases microgel balls.
[0045] Tannic acid (TA) and Fe 3+ Collaborative assembly and microgel deposition on silicon wafers, first configure 20mL buffer solution containing 100mg microgel beads, 87.7mg NaCl, 340.2mg TA and 54mg Fe 3+ The solution was added to the silicon chip, the liquid level was not over th...
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