Extract containing liquiritin and preparation method of extract

Abstract

The invention discloses a preparation method of an extract containing liquiritin. The preparation method comprises the following steps: taking a mixed solution of ethanol, isopropanol and acetone as an extraction solvent, controlling the volume ratio of ethanol to the isopropanol to the acetone to be (85-95): (4-10): (1-5), and further comprehensively extracting the extract containing liquiritin twice under different conditions, so as to obtain the extract containing liquiritin. The content rate of the liquiritin in the extract containing Liquiritin is 35.82% or above. Besides, a gradient heating mode is adopted in the first ultrasonic treatment process, so that the content of the liquiritin in the extract is further increased. Furthermore, the invention also discloses the extract containing the Liquiritin, obtained by the preparation method.

Description

technical field

[0001] The invention relates to the technical field of extraction and separation of traditional Chinese medicines, in particular to a preparation method for extracting a liquiritin-containing extract from licorice and the liquiritin-containing extract extracted by the method. Background technique

[0002] Liquiritin (Liquiritin, systematically named: 4',7-dihydroxyflavone-4'-O-β-D-glucopyranoside) is the most important flavonoid in licorice, belonging to dihydroflavonoids, Has strong pharmacological activity. Liquiritin has anti-oxidation, anti-arrhythmia, anti-ulcer, anti-virus, neuroprotection, myocardial cell membrane protection and other effects. Although liquiritin has a variety of pharmacological activities, many problems still need to be solved in order to develop it into a new drug, one of the main problems is the extraction process. For the extraction process, the types used in the prior art are various, as Chinese patent document CN101073595A disc...