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Antibacterial nano-microemulsion system, preparation method, application and application method

A nano-microemulsion and system technology, which is applied in the field of daily chemical industry, can solve problems that have not yet been discovered, and achieve the effects of easy operation, reducing irritation, and regulating odor

Pending Publication Date: 2021-01-15
广东华清园生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] At present, there is no relevant report on the market that uses nano-microemulsion embedding technology to mix litsea cubeba oil and borneol oil to make a powerful antibacterial nano-microemulsion system

Method used

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  • Antibacterial nano-microemulsion system, preparation method, application and application method
  • Antibacterial nano-microemulsion system, preparation method, application and application method
  • Antibacterial nano-microemulsion system, preparation method, application and application method

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preparation example Construction

[0049]Seefigure 1 , The preparation method of the antibacterial nano microemulsion system includes the following steps:

[0050]S100) Take Litsea cubeba oil and borneol oil in the above-mentioned mass percentages, and mix them evenly to prepare a nano-microemulsion oil phase;

[0051]S200) Take Tween 20, Tween 40, soybean lecithin, Tween 80 and deionized water in the above mass percentage to prepare a micellar solution. For details, please refer tofigure 2 , The micellar solution is prepared by the following steps:

[0052]S201) Take Tween 20, Tween 40, soybean lecithin and Tween 80 and add them to deionized water to obtain a first mixed solution.

[0053]S202) Take the first mixed liquid and heat it in a water bath and stir uniformly until a transparent and uniform micelle is formed, and a second mixed liquid is obtained.

[0054]S203) Take the second mixed solution and cool it to room temperature to obtain a micellar solution.

[0055]S300) Add the nano microemulsion oil phase to the micellar solut...

Embodiment 1

[0065](1) For the preparation of antibacterial nano microemulsion, please refer toFigure 4 , Including the following steps:

[0066]A100) Add 2.50% Litsea cubeba oil and 2.50% borneol oil to the No. 1 beaker, mix them, stir evenly, and prepare and form a nano-microemulsion oil phase.

[0067]A200) Then, add 66.50-73.00% deionized water to No. 2 beaker, then add 20.00% Tween 20, 2.00-3.50% soybean lecithin, and 1.00% Tween 80 to obtain the first mixed solution;

[0068]A300) Take the first mixed solution and place it in a water bath at 70-80° C. and heat it for 5-10 minutes, and stir at a rate of 500-700 rpm until a transparent and uniform micelle is formed to prepare a second mixed solution;

[0069]A400) Take the second mixed solution and cool it to room temperature in an ice-water bath to prepare a micellar solution.

[0070]A500) Then, add the oil phase of the nano microemulsion in the No. 1 beaker to the micellar solution in the No. 2 beaker, stir evenly at a speed of 500-700 rpm, and heat it ...

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Abstract

The invention discloses an antibacterial nano-microemulsion system, a preparation method, an application and an application method. The antibacterial nano-microemulsion system comprises the followingcomponents in percentage by mass: 1.00-10.00% of litsea cubeba oil; 1.00-10.00% of borneol oil; 10.00-20.00% of Tween 20; 0.00-5.00% of Tween 40; 1.00-6.00% of soybean lecithin; 0.00-5.00% of Tween 80; and the balance of deionized water. The preparation method of the antibacterial nano-microemulsion system comprises the following steps: adding a nano-microemulsion oil phase to a micelle solution,uniformly stirring the mixed solution, performing water bath heating, performing cooling to room temperature, and leaving a cooled product overnight to obtain the antibacterial nano-microemulsion system. The micelle solution is prepared from Tween 20, Tween 40, soybean lecithin, Tween 80 and deionized water; The nano-microemulsion oil phase is prepared from the litsea cubeba oil and the borneol oil by uniform mixing. The litsea cubeba oil and the borneol oil are embedded into the nano-microemulsion system through a nano-microemulsion technology. The litsea cubeba oil and the borneol oil are synergetic, and the property of theoil phase can be improved. The antibacterial nano-microemulsion system has excellent water dilutability and stability and has strong antibacterial effect.

Description

Technical field[0001]The invention relates to the field of daily chemical industry, in particular to a bacteriostatic nano microemulsion system, preparation method, application and application method.Background technique[0002]In recent years, with the rapid economic development and the continuous improvement of people’s living standards, consumers’ demand for food, cosmetics and other daily consumer products not only lie in their functions, utility, etc., but also proposes more about their senses and safety. High requirements, which means that manufacturers in order to meet the needs of consumers, the demand for additives that can improve the quality of their products is constantly increasing. As a kind of important additive raw materials, flavors have been widely used. Flavours can be divided into natural flavours and synthetic flavours according to their sources. Due to the large safety controversy of synthetic flavours, flavours of natural origin have attracted much attention due...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/54A61K9/107A61K47/26A61K47/24A61P31/04A61K8/06A61K8/92A61K8/55A61K8/49A61Q19/00A61Q17/00A23L27/00
CPCA61K8/068A61K8/4993A61K8/553A61K8/922A61K9/1075A61K36/185A61K36/54A61K47/24A61K47/26A61K2800/413A61Q17/005A61Q19/00A23L27/80A61P31/04A61K2300/00
Inventor 苏健裕凌凤清张勇范鹏辉吕满霞
Owner 广东华清园生物科技有限公司
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