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Application of active-mica-containing composition in preparation of medicine for improving activity of intracellular superoxide dismutase

A technology of dismutase activity and superoxide, applied in the field of biological health, can solve problems such as vacancies

Pending Publication Date: 2021-01-22
JILIN UNIV +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, at present, most of the substances used to increase superoxide dismutase are organic compounds, biological peptides or plant active parts, and there is almost no research on the effect of organic trace element fermentation broth on increasing the activity of superoxide dismutase in cells

Method used

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  • Application of active-mica-containing composition in preparation of medicine for improving activity of intracellular superoxide dismutase
  • Application of active-mica-containing composition in preparation of medicine for improving activity of intracellular superoxide dismutase
  • Application of active-mica-containing composition in preparation of medicine for improving activity of intracellular superoxide dismutase

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0028] A preparation method of a composition containing active mica, comprising the following steps:

[0029] (1) Accurately weigh the following raw materials: 4kg granite, 5kg water, 1kg greengage;

[0030] (2) Crush the granite to 0.5-0.8 cm and clean it with a vibrator; remove the core of the plum fruit;

[0031] (3) Granite, water, and green plums are added to the fermenter, mixed and fermented at 45°C for 140 days to obtain a mixture;

[0032] (4) The mixture is filtered, and the obtained filtrate is a composition containing active mica.

Embodiment 2

[0034] A preparation method of a composition containing active mica, comprising the following steps:

[0035] (1) Accurately weigh the following raw materials: 4kg limestone, 5kg water, 1kg greengage;

[0036] (2) Crush the granite to 0.5-0.8 cm and clean it with a vibrator; remove the core of the plum fruit;

[0037] (3) Granite, water, and green plums are added to the fermenter, mixed and fermented at 45°C for 140 days to obtain a mixture;

[0038] (4) The mixture is filtered, and the obtained filtrate is a composition containing active mica.

Embodiment 3

[0040] A preparation method of a composition containing active mica, comprising the following steps:

[0041] (1) Accurately weigh the following raw materials: 4kg granite, 5kg water, 2kg greengage;

[0042] (2) Crush the granite to 0.5-0.8 cm and clean it with a vibrator; remove the core of the plum fruit;

[0043] (3) Granite, water, and green plums are added to the fermenter, mixed and fermented at 45°C for 140 days to obtain a mixture;

[0044] (4) The mixture is filtered, and the obtained filtrate is a composition containing active mica.

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Abstract

The invention provides application of an active-mica-containing composition in preparation of a medicine for improving activity of intracellular superoxide dismutase and belongs to the technical fieldof biological big health. According to the application of the active-mica-containing composition in the preparation of the medicine for improving the activity of the intracellular superoxide dismutase, the oxidation resisting and aging resisting properties of the active-mica-containing composition are judged through acting on SGC-7901 cells for 24h with active-mica-containing compositions dilutedin different proportions, thoroughly cracking the cells, then, taking supernatants as samples to be detected, and detecting superoxide dismutase activity of the samples by employing a total-SOD activity detection method (WST-8 method), and it is proven that the active-mica-containing composition can be used for improving the activity of the intracellular superoxide dismutase and can maintain normal growth forms of the cells under the condition of certain degree of dilution. By applying the active-mica-containing composition to improvement on the activity of the intracellular superoxide dismutase, a basis is provided for application in big health industries such as human free radical clearing, aging resisting and facial beautification in future.

Description

technical field [0001] The invention belongs to the technical field of biological health, and in particular relates to the application of a composition containing active mica in the preparation of drugs for improving the activity of superoxide dismutase (SOD) in cells. Background technique [0002] Trace elements such as organic germanium are distributed in rocks, soil, crust and water bodies. Part of the enzymes in the human body and the white and gray matter in the brain require the participation of organic trace elements. Hericium erinaceus, Ganoderma lucidum, ginger, safflower, fennel, soybeans, etc. are all foods that contain more organic trace elements. Organic trace elements have biological activities such as anti-tumor, anti-inflammatory, scavenging free radicals, anti-lipid peroxidation, anti-osteoporosis, and anti-rheumatic arthritis. In recent years, the research on the synthesis of organic trace elements has gradually deepened, and many related anticancer drugs...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/736A61K33/06A61P29/00A61P35/00A61P37/02A61P39/06A61K8/9789A61K8/26A61Q19/06A23L33/105A23L33/16A23L2/38
CPCA61K33/06A61K36/736A61P29/00A61P35/00A61P37/02A61P39/06A61K8/9789A61K8/26A61Q19/06A23L33/105A23L33/16A23L2/38A61K2236/19A23V2002/00A61K2300/00A23V2200/302A23V2200/318A23V2200/308A23V2200/324
Inventor 施维郝翠婷王希峰
Owner JILIN UNIV
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