The invention provides an anti-alcoholism beverage using tea saponin as a main body. The anti-alcoholism beverage comprises the following ingredients: tea saponin, extracts from pueraria, extracts from pericarpium citri reticulatae, jujube date polysaccharide, extracts from medlar, extracts from haw apple, honey, citric acid, vitamin B1, vitamin B6 and vitamin C. The disclosed anti-alcoholism beverage is high in raw material utilization ratio, low in cost and good in taste, and can protect liver and stomach. According to the anti-alcoholism beverage provided by the invention, the drunkenness endurance time of mice can be prolonged, the sleeping time is reduced, the concentration of ethyl alcohol in blood can be obviously reduced, the activity of in vivo glutathione peroxidase and the activity of superoxide dismutase after drinking are increased, the metabolism of the ethyl alcohol and the elimination of free radicals in the liver are accelerated, the generation of peroxides is reduced, the increase of malondialdehyde content caused by alcohol is inhibited, the activity of ethanol dehydrogenase is further increased to a certain extent, the metabolism of the ethyl alcohol in the liver is quickened, the damage of the ethyl alcohol on human bodies is reduced, and the anti-alcoholism beverage has good taste.