30 results about "Morbidity index" patented technology

Methods, systems, and apparatus for assessing a state of a comorbidity associated with a primary disease are provided. The methods comprise receiving at least one autonomic index, neurologic index, stress marker index, psychiatric index, endocrine index, adverse effect of therapy index, physical fitness index, or quality of life index of a patient; comparing the at least one index to at least one reference value; and assessing a state of a body system of the patient that is a site of the comorbidity, based on the comparison. A computer readable program storage device encoded with instructions that, when executed by a computer, perform the method described above is also provided. A medical device system capable of implementing the method described above is also provided.

Methods, systems, and apparatus for assessing a state of an epilepsy disease or a comorbidity thereof are provided. The methods comprise receiving at least one autonomic index, neurologic index, stress marker index, psychiatric index, endocrine index, adverse effect of therapy index, physical fitness index, or quality of life index of a patient; comparing the at least one index to at least one reference value; and assessing a state of an epilepsy disease or a body system of the patient based on the comparison. A computer readable program storage device encoded with instructions that, when executed by a computer, perform the method described above is also provided. A medical device system capable of implementing the method described above is also provided.

Transcutaneous electrical nerve stimulation devices and magnetic stimulation devices are disclosed, along with methods of treating medical disorders using energy that is delivered noninvasively by such devices. The disorders comprise migraine and other primary headaches such as cluster headaches, including nasal or paranasal sinus symptoms that resemble an immune-mediated response (“sinus” headaches). The devices and methods may also be used to treat rhinitis, sinusitis, or rhinosinusitis, irrespective of whether those disorders are co-morbid with a headache. They may also be used to treat other disorders that may be co-morbid with migraine or cluster headaches, such as anxiety disorders. In preferred embodiments of the disclosed methods, one or both of the patient's vagus nerves are stimulated non-invasively. In other embodiments, parts of the sympathetic nervous system and / or the adrenal glands are stimulated.

Methods and devices reroute chyme to induce intestinal brake in order to improve the effectiveness of bariatric surgical procedures and to improve comorbidity resolution. A bowel is manipulated to provide a shortened path for chyme to travel to the ileum. These methods and devices of rerouting chyme to induce intestinal brake may comprise one or more of a surgical procedure, an implanted device, or a combination of an implant with an improved surgical procedure.

Methods and devices reroute chyme to induce intestinal brake in order to improve the effectiveness of bariatric surgical procedures and to improve comorbidity resolution. A bowel is manipulated to provide a shortened path for chyme to travel to the ileum. These methods and devices of rerouting chyme to induce intestinal brake may include one or more of a surgical procedure, an implanted device, or a combination of an implant with an improved surgical procedure.

Disclosed is a method and composition for nutritionally improving glucose and insulin balance in an individual. The invention further provides a method for treating a comorbidity of diabetes. In one embodiment, the invention provides a nutritional formulation comprising: a protein source; a fat source; and a carbohydrate source, wherein the protein source, the fat source, and the carbohydrate source are in a ratio of about 1:1:1, each comprising about one third of the total calories of the composition.

The invention discloses an epidemic disease morbidity index prediction method, device and equipment and a readable storage medium, and the method comprises the steps: obtaining public opinion data andepidemic disease data related to epidemic diseases, and calculating the epidemic disease morbidity index through the epidemic disease data; Inputting the epidemic disease morbidity index and target feature data extracted from the public opinion data and the epidemic disease data into a preset machine learning model and a deep learning model to obtain a predicted morbidity index corresponding to the epidemic disease; And sending alarm information to the disease control center system when the predicted attack index is greater than a preset threshold value, so that the disease control center system prompts workers to take epidemic prevention measures according to the alarm information. Through intelligent decision making, the epidemic index of the epidemic disease is automatically predicted,when the epidemic index is high, alarm information is sent out in time, and workers can take epidemic disease prevention measures in time conveniently.

Methods, systems, and apparatus for assessing a state of a comorbidity associated with a primary disease are provided. The methods comprise receiving at least one autonomic index, neurologic index, stress marker index, psychiatric index, endocrine index, adverse effect of therapy index, physical fitness index, or quality of life index of a patient; comparing the at least one index to at least one reference value; and assessing a state of a body system of the patient that is a site of the comorbidity, based on the comparison. A computer readable program storage device encoded with instructions that, when executed by a computer, perform the method described above is also provided. A medical device system capable of implementing the method described above is also provided.

Systems and methods for healthcare assurance system are provided. A first set of confidential health information for an identified patient may be accessed, may be derived from a first data source, and may include first medical indicia corresponding to an indication of a first health condition and / or an indication of a first healthcare service. A second set of confidential health information may be accessed, may be derived from a second data source, and may include second medical indicia corresponding to an indication of a second health condition and / or an indication of a second healthcare service. Healthcare rules that include criteria indicating comorbidity conditions may be accessed. The first and second sets of confidential health information may be correlated to the healthcare rules. A comorbidity condition may be identified based on the first medical indicia, the second medical indicia, and the correlating. A prompt regarding the comorbidity condition may be provided.

A mapping matrix, which maps from original features of an electronic health record database to higher level latent factors, is initialized. For each of one or more target diseases, regression coefficients are updated over the higher level latent factors, based on said initialized mapping matrix, a data matrix containing said original features, and a label vector of corresponding responses. Said mapping matrix is updated based on said updated regression coefficients. Said steps of updating said regression coefficients and updating said mapping matrix are repeated until convergence is achieved, to obtain a final mapping matrix and a final set of regression coefficients.

The present invention relates to methods of treating subjects preparing to undergo surgery or methods of treating chronic disease and methods for reducing transfusions and a computer readable storage medium and a physical computing device for carrying out these methods which include: a) receiving a profile of said subject, in a physical computing device, including a level of hemoglobin of said subject, level of creatinine of said subject, and information regarding current or past history of disease; b) applying said level of hemoglobin and said level of creatinine, in said physical computing device, to determine level of transfusion risk; c) applying said information regarding current or past history of disease of said subject, in said physical computing device, to determine level of comorbidity; d) applying said level of hemoglobin, said level of transfusion risk, and said level of comorbidity, in said physical computing device, to determine a patient care plan.

The invention discloses a cross-platform clinical big data analysis and display system. The system comprises a servo, an academic-edition website, a trade-edition website, an academic-edition embedded application and a trade-edition embedded application. The servo comprises a clinical medical data collection subsystem, an expert verification subsystem, an automatic acceleration subsystem, an automatic regressive diagnosis subsystem and an automatic statistics subsystem. Through the system, efficient and precise statistical analysis of clinical disease big data can be realized, medical big data can be utilized to perform longitudinal and transverse research quickly, data results can be recombined objectively, multiple models can be utilized for statistical analysis and display of the relation between different gendersand comorbidity, the relation between different age groups and comorbidity, the relation between diseases, the relation between drugs and diseases and the relation between drugs and operations, past theories can be verified, new theories can be proposed, and the system can be applied to the fields of medical treatment, insurance, medical research, pharmaceuticals, etc.

Systems and methods for healthcare assurance system are provided. A first set of confidential health information for an identified patient may be accessed, may be derived from a first data source, and may include first medical indicia corresponding to an indication of a first health condition and / or an indication of a first healthcare service. A second set of confidential health information may be accessed, may be derived from a second data source, and may include second medical indicia corresponding to an indication of a second health condition and / or an indication of a second healthcare service. Healthcare rules that include criteria indicating comorbidity conditions may be accessed. The first and second sets of confidential health information may be correlated to the healthcare rules. A comorbidity condition may be identified based on the first medical indicia, the second medical indicia, and the correlating. A prompt regarding the comorbidity condition may be provided.

The invention discloses a traditional Chinese medicine compound for improving sleep quality, a preparation method and application thereof. The traditional Chinese medicine compound is prepared from the following components in parts by weight: 10-25 parts of agastache rugosus, 10-25 parts of herba eupatorii, 25-40 parts of flos albizziae, 2-7 parts of agilawood, 4-10 parts of frankincense and 4-10parts of myrrh. The compound is also prepared from medicinal materials, such as spica prunellae, fresh ossa draconis, raw oyster, flos chrysanthemi, ramulus et uncus uncariae, amber powder, radix polygalae, poria with hostwood, rhizoma acori graminei, radix curcumae and roses. The combination of agastache rugosus, herba eupatorii, flos albizziae, agilawood, frankincense and myrrh is taken as a traditional Chinese medicine formula. Besides, proper traditional Chinese medicinal materials can be added and reduced according to specific manifestation difference of insomnia comorbidity. A compound formula suitable for insomniacs with different comorbidities is acquired. A clinical test proves that the traditional Chinese medicine compound has a sleep-improving function as good as that of oral drugs, can quickly take effect and is free from toxic side effect.

Described are systems that include at least one sub-system to track, measure, monitor and reward adolescents and young adults for performing daily physical activities, which include before-school, in-school, after-school, sports and activities of daily living. The system offers adolescents the opportunity to track their integrated physical activity level (I-PAL) scores over their adolescent years. Also described are systems that include at least one sub-system that supports the four pillars of juvenile diabetes management, which include managing medications, monitoring blood glucose levels, documenting eating habits and tracking integrated physical activity levels. Another embodiment describes systems to manage childhood obesity that includes documenting eating habits, tracking integrated physical activity levels, offering educational and motivational information and managing comorbidities related to childhood obesity. Also included are embodiments that describe a system to help physical education teachers in schools to help students set goals, monitor class progress, objectively grade the students performance and provide a lifetime score that can be carried from one grade level to the next. The system accomplishes this by aggregating physical acidity data from a variety of sources. The described systems also allow adolescents and young adults to form health groups and socialize their progress in a safe environment to motivate themselves and their social peers by setting health goals.

The present Invention relates to methods of treating subjects preparing to undergo surgery or methods of treating chronic disease and methods for reducing transfusions and a computer readable storage medium and a physical computing device for carrying out these methods which include: a) receiving a profile of said subject, in a physical computing device, including a level of hemoglobin of said subject, level of creatinine of said subject, and information regarding current or past history of disease; b) applying said level of hemoglobin and said level of creatinine, in said physical computing device, to determine level of transfusion risk; c) applying said information regarding current or past history of disease of said subject, in said physical computing device, to determine level of comorbidity; d) applying said level of hemoglobin, said level of transfusion risk, and said level of comorbidity, in said physical computing device, to determine a patient care plan.

An apparatus is provided which improves the evaluation of a patient's vasculature by applying a correction to invasively acquired intravascular measurement data of a vessel of interest on the basis of archived patient data of said patient from a patient database. By correcting the measurement data, co-morbidities of the patient which may influence the intravascular measurement results are accounted for.

The present invention is directed to a system and a non-transitory computer readable medium for managing use of hospitalization healthcare resources. Specifically, the embodiments of the invention may accept information from one or more sources, select a population unit, define one or more population units according to enhanced comorbidity, assign one or more values to the one or more population units defined according to enhanced comorbidity, and generate a graphical user interface on which one or more values may be depicted. Some embodiments may be directed to a system and methods for determining whether one or more population units may exceed a use of hospitalization healthcare resources threshold.

The invention provides blood-brain barrier shuttles comprising monoclonal antibody 5C1 and related antibodies linked to a monovalent binding entity for a blood-brain barrier receptor. The 5C1 antibody binds to an epitope within residues 118-126 of alpha-synuclein. The antibodies are useful, for example, for treating and / or diagnosing synucleinopathies including Lewy body diseases, such as Parkinson's disease, diffuse Lewy body disease (DLBD), Lewy body variant of Alzheimer's disease (LBV),Alzheimer's and Parkinson's disease comorbidity, and pure autonomic failure, as well as multiple system atrophy (MSA).

The invention provides a method for establishing a horseshoe kidney animal model. The method comprises: injecting a certain amount of retinoic acid solution at one time in the early pregnancy of the pregnant animal, and routinely feeding and giving birth to obtain the horseshoe kidney animal model. The method for creating an animal model of horseshoe kidney of the present invention has good experimental repeatability, and provides an experimental tool and platform for mechanism research for abnormal kidney development such as horseshoe kidney. Surgical operation and drug evaluation provide an extremely close and convenient experimental tool platform and scientific basis.

Methods are provided of treating obesity or an obesity comorbidity in a mammalian subject comprising administering to the subject an amount of an agent effective to treat obesity or the obesity comorbidity, which agent inhibits (i) IκB kinase β (IKKβ) activation of nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) or (ii) Notch signaling in a manner so as to permit the agent to enter the hypothalamus of the subject. Assays are also provided for identifying candidate agents for treating obesity.

An association between psychiatric disorders and disorders comorbid with psychiatric disorders, and genetic markers in the 8p23 genomic region is described. Markers are also provided to diagnose or detect a susceptibility to disorders comorbid with panic disorder and independently of comorbidity with panic disorder. Methods and surrogate markers for detecting the orientation of the Inv8p23 inversion fragment, thereby diagnosing psychiatric disorders or comorbid disorders or a susceptibility to psychiatric disorders or comorbid disorders, are also disclosed. The methods described herein are also useful for determining responsiveness of drugs useful for treating psychiatric disorders.

A method for selecting a device adapted to treat disordered breathing in a patient with one or more comorbid diseases is provided. More particularly, a method for reducing a potential group of patient interface devices adapted to treat disordered breathing of a patient to an optimized group, includes: prescreening the patient; determining a measure of a comorbidity of the patient from the prescreening; comparing the measure of the comorbidity to a corresponding predetermined threshold; and determining the optimized group from the potential group. The optimized group may include a reduced number of devices from which a particular device is then selected or may include only a single particular device.

The invention relates to a photovoltaic intelligent recognition immune system for yaks and a control method thereof and belongs to the technical field of immune prevention and treatment. The characteristic that highland environment is long in illumination time and high in illumination intensity is utilized fully, the problem that high-altitude areas are low in solar energy utilization rate is solved, and solar energy is utilized to power equipment; a camera is adopted to perform image collection on the yaks to extract body features of the yaks like ear ring, shoulder height and body length of the yaks, collected images are binarized through Raspberry Pi, then subjected to computer image calibration and computation and transmitted to an upper computer and a database, and the immune system is started to disinfect the yaks, so that the problems that human-livestock comorbidity is easy to cause and animals are prone to agitated to cause damage to people due to conventional manual aerosol immunization are solved, and the problem that manual agent liquid spraying is high in labor intensity, low in operating efficiency and high in labor cost is solved.

Methods are provided of treating obesity or an obesity comorbidity in a mammalian subject comprising administering to the subject an amount of an agent effective to treat obesity or the obesity comorbidity, which agent inhibits (i) IκB kinase (IKKβ) activation of nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) or (ii) Notch signaling, in a manner so as to permit the agent to enter the hypothalamus of the subject. Assays are also provided for identifying candidate agents for treating obesity’.

The invention discloses a traditional Chinese medicine composition for treating headache and depression comorbidity. The traditional Chinese medicine composition is prepared from the following components: 12g of rhizoma Chuangxiong, 10g of radix bupleuri, 10g of cortex albiziae, 10g of radix astragali and 6g of scorpion. When in use, the traditional Chinese medicine components are decocted with water until the volume is 300ml, and one dose is orally taken by a patient in the morning and at night every day. Every 8 weeks take a treatment course. Compared with the prior art, the traditional Chinese medicine composition for treating the headache and depression comorbidity is prepared from the rhizoma Chuangxiong, radix bupleuri, cortex albiziae, radix astragali and scorpion, all traditional Chinese medicinal components play a synergistic effect, so that the chronic headache and complicated depression state can be treated, and the traditional Chinese medicine composition is safe, reliable,nontoxic and free from side effect.

An apparatus comprises an activity monitor for measuring physical activity of a subject. The activity monitor is configured to obtain a first set of physical activity data over a first time period, for example during the day, and a second set of physical activity data over a second time period, for example during the night. A processor processes the data obtained by the activity monitor to calculate a physical activity ratio which is the ratio of the physical activity measured during the first time period to the physical activity measured in the second time period. The processor also calculates a first overall value which represents an activity level of the subject during the first time period. The physical activity ratio together with the first overall value may be used to assess the severity of symptoms of COPD displayed by a subject or to identify respiratory disease comorbidity information for example psychological issues such as low motivation, or sleep quality issues displayed by the subject.