Metal coordination compound, intermediate, preparation method and application thereof
A technology of metal complexes and coordination bonds, applied in the preparation of imino compounds, nickel organic compounds, chemical instruments and methods, etc.
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Embodiment 1
[0314] The synthesis of embodiment 1 compound II
[0315] The preparation method of compound II-1 is as follows:
[0316] Under the action of 12.5g (125mmol) acetylacetone and 44.3g (250mmol) 2,6-diisopropylaniline under the action of 10.6mL (125mmol) concentrated hydrochloric acid, 44.2g of compound IV-1 can be successfully obtained with a yield of 81%. The compound is oxidized by oxygen under the action of 1 equivalent of copper acetate to obtain compound III-1, followed by AlMe 3 The addition gave product II-1 with a total yield of 65% in three steps and a total of 36 g.
[0317]
[0318] The preparation method of compound II-11 is as follows:
[0319] Dissolve 19.4g (193.8mmol) of acetylacetone and 33.8g (190.87mmol) of 2,6-diisopropylaniline in 100mL of toluene, add about 1.0g (2%) of p-toluenesulfonic acid monohydrate, and heat up to reflux Divide water until no water comes out. Then the solvent was removed under reduced pressure, and the residue was distilled und...
Embodiment 2
[0378] The synthesis of embodiment 2 complex I-1
[0379] Compound II-1 (0.67 g, 1.5 mmol) in tetrahydrofuran was slowly added dropwise to KH (0.12 g, 3.0 mmol) in tetrahydrofuran at room temperature, and a large number of bubbles were generated during the dropwise addition. The dropwise addition was completed within ten minutes, and after 12 hours of reaction, it was filtered through diatomaceous earth. The filtrate was slowly added dropwise to NiBr at room temperature 2 (DME) (0.92g, 3.0mmol) in tetrahydrofuran solution, reacted overnight. The solvent was removed under reduced pressure, toluene was added, KBr was removed by filtration, the filtrate was concentrated and recrystallized by adding a small amount of hexane to obtain 1.02 g of red solid I-1 with a yield of 83%.
[0380]
[0381] Elemental analysis: measured (calculated value): C: 48.25 (48.09); H: 6.16 (6.27); N: 3.11 (2.95).
[0382] The coordinating solvent tetrahydrofuran can be removed by conventional dr...
Embodiment 3
[0383] The synthesis of embodiment 3 complex I-2~I-54
[0384] Obtain other compound I-2 (productive rate 65%) with the experimental method identical with embodiment 2; I-3 (productive rate 71%); I-4 (productive rate 59%); I-5 (productive rate 63% ); I-6 (yield 74%); I-7 (yield 76%); I-8 (yield 64%); I-9 (yield 67%); I-10 (yield 55% ); I-11 (55% yield); I-12 (75% yield); I-13 (72% yield); I-14 (58% yield); I-15 (66% yield ); I-16 (61% yield); I-17 (72% yield); I-18 (54% yield); I-19 (67% yield); I-20 (77% yield ); I-21 (yield 68%); I-22 (yield 71%); I-23 (yield 12%); I-24 (yield 38%); I-25 (yield 40% ); I-26 (45% yield); I-27 (50% yield); I-28 (48% yield); I-29 (47% yield); I-30 (36% yield ); I-31 (60% yield); I-32 (3% yield); I-33 (23% yield); I-34 (59% yield); I-35 (16% yield ); I-36 (yield 30%); I-37 (yield 56%); I-38 (yield 54%); I-39 (yield 12%); I-40 (yield 18% ); I-41 (45% yield); I-42 (43% yield); I-43 (25% yield); I-44 (15% yield); I-45 (19% yield ); I-46 (23% y...
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