Guava hypoglycemic formula and preparation method and application thereof

A guava and hypoglycemic technology, applied in the field of hypoglycemic, can solve problems such as chronic dysentery, prolapse of the anus, scabies due to dampness, traumatic bleeding, low hypoglycemic activity, discarding of young fruits, etc., to reduce the activity of α-glucosidase, Improve insulin resistance and promote insulin secretion

Pending Publication Date: 2021-03-16
深圳市清生元生物技术股份有限公司
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Guava leaves can be used for medicine, and have the functions of stopping dysentery, stopping bleeding, and invigorating the stomach. They are used to treat diarrhea, chronic dysentery, prolapse of the anus, scabies caused by dampness, and traumatic bleeding; the leaves can be used as tea after being boiled and dried in the sun. , guava fresh fruit, raw materials are sufficient, the price is low, but it is not easy to store, and the young fruit is often discarded in the production process, and the raw materials are not fully utilized. At present, there are few reports on the hypoglycemic activity of guava fruit extract

Method used

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  • Guava hypoglycemic formula and preparation method and application thereof
  • Guava hypoglycemic formula and preparation method and application thereof
  • Guava hypoglycemic formula and preparation method and application thereof

Examples

Experimental program
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Embodiment

[0024] 1. Preparation of water extract

[0025] Take commercially available guava, corn silk, dandelion, lotus leaves, and mulberry leaves, which are naturally air-dried or air-dried at low temperature, crushed through a 60-mesh sieve, heated and extracted with 10-20 times of water, concentrated and then freeze-dried to obtain five kinds of water extract powders .

[0026] 2. Orthogonal experiment for the preparation of different guava hypoglycemic formulas

[0027] Orthogonal experimental method to optimize the optimal ratio of guava, corn silk, dandelion, lotus leaf, and mulberry leaf in the hypoglycemic formula, using orthogonal experimental design, using 5 drugs as 5 factors, and 4 levels for each factor As shown in Table 1, using L16(4 5 ) orthogonal table for experimental design, accurately weigh the water extract powder of medicinal materials, weigh different grams of water extract according to the ratio in the orthogonal table, mix well and set aside.

[0028] Table...

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PUM

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Abstract

The invention discloses a guava hypoglycemic formula and a preparation method and application thereof. The guava hypoglycemic formula comprises the following components by mass: 3-12 parts of guava aqueous extract, 1-4 parts of corn stigma aqueous extract, 1-10 parts of dandelion aqueous extract, 1.5-3 parts of lotus leaf aqueous extract and 2-5 parts of mulberry leaf aqueous extract. Guava and corn stigma used in the guava hypoglycemic formula are common food sources, dandelion, lotus leaves and mulberry leaves are all medicinal and edible raw materials, the formula can reduce the activity ofalpha-glucosidase in vitro and has hypoglycemic effect, corn stigma and lotus leaves have the effect of improving insulin resistance of fat rats, and mulberry leaves can promote insulin secretion andprotect islet cells. According to the invention, the guava extract, the dandelion extract and other extracts are mixed for use, so that the formula has a better effect of reducing the activity of alpha-glucosidase, and provides a basis for development and application of hypoglycemic products in the fields of food, health care products, medicine and the like in the future.

Description

technical field [0001] The invention relates to the technical field of hypoglycemia, in particular to a guava hypoglycemic formula and its preparation method and application. Background technique [0002] Diabetes is one of the most common endocrine diseases in the world, which seriously threatens human health. It is the third largest chronic non-communicable disease after tumors and cardiovascular diseases. It has high mortality, disability and medical burden. It is a common public health problem faced by countries all over the world. In the treatment of diabetes, diet therapy is the basis for the treatment of various types of diabetes. It can lower blood sugar and reduce the burden on islet cells. It is equally important as drug therapy. Effective diet control can reduce and delay the occurrence of complications. Diabetic patients' diet control and fasting of sugary foods lead to unreasonable diets, insufficient nutritional intake, metabolic disorders and physical decline...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/899A61P3/10
CPCA61K36/288A61K36/605A61K36/61A61K36/62A61K36/899A61K2236/331A61P3/10A61K2300/00
Inventor 邹先伟李倩
Owner 深圳市清生元生物技术股份有限公司
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