Polypeptide RL-PP10 capable of resisting oxidative damage and protecting skin and application thereof

Abstract

The invention discloses a polypeptide RL-PP10 capable of resisting oxidative damage and protecting skin and an application of the polypeptide RL-PP10. The amino acid sequence of the polypeptide RL-PP10 with the oxidative damage resistance and the skin protection activity is PPRWPKEECP. The application is the application of the antioxidant injury skin protection active polypeptide RL-PP10 in preparation of antioxidant cosmetics, health foods and medicines. The natural polypeptide RL-PP10 with skin light damage resistance and oxidative stress activation is identified from skin secreta of euphorbia helioscopia in Yunnan, and the polypeptide has the characteristics of high activity, high stability and the like, so that the polypeptide RL-PP10 with oxidative damage resistance and skin protection activity has great medical application potential. The polypeptide RL-PP10 disclosed by the invention has the beneficial characteristic that the polypeptide RL-PP10 can be used as a candidate sourceof an anti-ultraviolet medicine.

Description

Technical field [0001] The invention belongs to the field of biomedical technology, and more particularly to an antioxidant damage to skin protection active polypeptide RL-PP10 and its application thereof. Background technique [0002] Excessive exposure to ultraviolet (UV) radiation is one of the main reasons for a variety of skin diseases such as sunburning, photocondens, skin cancer, etc., of which UVB (290-320 nm) radiation is most important to skin damage. Resist UVB radiation is one of the main methods of protecting skin light injury, so in recent years, protector with antioxidant function has come to life. In terms of skin antioxidants, there are mostly characteristics of low activity, high synthesis costs, and easy decomposition, and the number cannot meet the needs of people with increasing skin oxidation damage. Therefore, the development of new natural antioxidants is critical. The polypeptide antioxidant is widely attracted to people's attention due to its high activi...

AI Technical Summary

Problems solved by technology

At present, we have extracted a variety of natural active peptides from amphibian skin secretions, including antiviral peptides, anti-oxidative damage peptides, antibacterial active peptides, etc., but the number of these peptides is far from enough for the treasure house of amphibian skin secretions. There are many more natural peptides to be developed

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